Preparation of polymeric surfaces via covalently attaching polymers
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-002/54
출원번호
US-0447802
(1989-12-08)
발명자
/ 주소
Guire Patrick E. (Eden Prairie MN) Dunkirk Shawn G. (Eden Prairie MN) Josephson Mark W. (Richfield MN) Swanson Melvin J. (Carver MN)
출원인 / 주소
Bio-Metric Systems, Inc. (Eden Prairie MN 02)
인용정보
피인용 횟수 :
262인용 특허 :
3
초록▼
A method wherein surfaces are provided with desired characteristics of a polymer by covalently bonding polymer molecules to the surface through external activation of latent reactive groups carried by the polymer molecules is disclosed. The initial surfaces are free of chemical groups added by surfa
A method wherein surfaces are provided with desired characteristics of a polymer by covalently bonding polymer molecules to the surface through external activation of latent reactive groups carried by the polymer molecules is disclosed. The initial surfaces are free of chemical groups added by surface pretreatment and which chemically participate in the covalent bonding process. This application is a divisional of application Ser. No. 223,149, filed July 22, 1988 now abandoned, which is a continuation-in-part of U.S. application Ser. No. 138,226, filed Dec. 24, 1987 now abandoned, which is a continuation-in-part of U.S. application Ser. No. 920,567, filed Oct. 17, 1986 now abandoned and of U.S. Ser. No. 108,765, filed Oct.15, 1987 now U.S. Pat. No. 4,973,493 which is a continuation-in-part of U.S. application Ser. No. 428,074 now U.S. Pat. No. 4,722,906 filed Sept. 29, 1982, and of U.S. application Ser. No. 920,567 filed Oct. 17, 1986.
대표청구항▼
A method of providing a solid surface with desired characteristics comprising choosing a synthetic polymer having the desired characteristics, contacting the solid surface with a composition comprising a solution of a plurality of molecules of the synthetic polymer possessing the desired characteris
A method of providing a solid surface with desired characteristics comprising choosing a synthetic polymer having the desired characteristics, contacting the solid surface with a composition comprising a solution of a plurality of molecules of the synthetic polymer possessing the desired characteristics, some of the molecules of the synthetic polymer having covalently bonded thereto at least one latent reactive group capable of generating an active specie selected from the group consisting of free radicals, carbenes, nitrenes and excited states of ketones, in response to activation of the latent reactive groups, by application of an external stimulus to covalently bond the molecules of the synthetic polymer through the latent reactive groups to said solid surface, the average ratio of latent reactive groups, to an extended chain length, in Angstroms, of the molecules of the synthetic polymer being in the range of about 1/10 to about 1/700 and the molecules of the synthetic polymer each having an end, and each molecule of the polymer having no latent reactive groups capable of active specie generation in response to activation by application of an external stimulus to covalently bond to the surface with 10 Angstroms from such end, the composition enabling the molecules of the synthetic polymer to be so spatially oriented as to enable the latent reactive groups to come into covalent bonding proximity with the solid surface, and thereafter activating the latent reactive groups by application of the external stimulus to covalently bond the molecules of the synthetic polymer to the solid surface.
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Lowery, Michael D; Hoffmann, Laurent; Kobrin, Boris; Nowak, Romuald; Chinn, Jeffrey D; Yi, Richard C, Controlled vapor deposition of biocompatible coatings for medical devices.
Loeffler, Joseph P.; Rapp, David; Briones, Victor; Bitdinger, Ralf; Klimowicz, Michael, Convertible fluid feed system with comformable reservoir and methods.
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Katoot Mohammad W. ; Goodan Katoot ; administrator by Karen Robbyn ; Katoot ; administrator by Ali Maroof ; Katoot ; administrator by Ahmed Maroof, Method and composition for modifying the surface of an object.
Amon Michael,DEX ; Bolz Armin,DEX ; Mussig Dirk,DEX, Method of attaching heparin to, and immobilizing it on, inorganic substrate surfaces of cardiovascular implants.
Zhong Sheng-Ping (Farum DKX), Method of providing a substrate with a hydrophilic coating and substrates, particularly medical devices, provided with s.
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Yang, Tom Weisan; Bhamidipati, Arunashree; Bordunov, Andrei V.; Knittle, James Eugene; O'Neill, Roger A.; Voss, Karl O., Methods and devices for analyte detection.
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Fink, James B.; Power, John; Ivri, Ehud; Smith, Niall; Dunne, Paul; O'Sullivan, Gavan; Moran, Declan; Gibbons, Keith, Methods and systems for operating an aerosol generator.
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Yan Mingdi ; Keana John F. W. ; Karapetrov Goran ; Sevrain Christopher J-P ; Wybourne Martin N., Methods for functionalizing and coating substrates and devices made according to the methods.
Berry,Leslie Roy; O'Brodovich, legal representative,Hugh; Chan,Anthony Kam Chuen; Andrew, deceased,Maureen, Methods of coating a device using anti-thrombin heparin.
Swanson Melvin J. ; Amos Richard A. ; Swan Dale G. ; Opperman Gary W., Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom.
Clapper, David L.; Swanson, Melvin J.; Hu, Sheau-Ping; Amos, Richard A.; Everson, Terrence P., Polybifunctional reagent having a polymeric backbone and latent reactive moieties and bioactive groups.
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