초록 ▼

A roller bottle for cell growth contains a wall formed of a plurality of corrugations, preferably symmetrical and perpendicular to the axis of the bottle, and having at least one drain channel formed by at least one and preferably two opposed flat axial, uncorrugated panels and optionally containing

A roller bottle for cell growth contains a wall formed of a plurality of corrugations, preferably symmetrical and perpendicular to the axis of the bottle, and having at least one drain channel formed by at least one and preferably two opposed flat axial, uncorrugated panels and optionally containing axial reinforcement ribs provided along the outer edge of the corrugations. The corrugations are discontinuous along the inside surface of the panels to form drainage channels. The surface area of the bottle is 110 to 500% larger than an uncorrugated bottle having the same exterior dimensions.

대표청구항 ▼

A roller bottle for tissue culture growth comprising in combination: a substantially cylindrical wall section having a central axis and containing a pleated segment having an upper edge and a lower edge; the pleated segment including at least one unpleated, axial panel for forming a drain channel fo

A roller bottle for tissue culture growth comprising in combination: a substantially cylindrical wall section having a central axis and containing a pleated segment having an upper edge and a lower edge; the pleated segment including at least one unpleated, axial panel for forming a drain channel for emptying the contents of the bottle, a plurality of unpleated, axial support ribs, each rib being narrower than said panel and a plurality of pleats disposed crosswise to the axis of the bottle, each of the pleats containing an outer rim disposed in a common cylindrical plane and forming a trough on the inside surface of the segment; each of the panels being connected to said troughs, being disposed no nearer to said central axis than said common cylindrical plane and extending substantially from the upper edge to the lower edge of the cylindrical segment said panels and support ribs forming at least 5% of the circumference of cylindrical wall section; said roller bottle having an inner surface area at least 110% the surface area of a roller bottle having an unpleated cylindrical segment having the same external diameter said roller bottle having an interior surface that has been radiation treated to be wettable for cell attachment and growth; a top section of the bottle having a neck connected to the cylindrical wall section; and a bottom section of the bottle connected to the cylindrical wall section.