$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Heparin derivatives and process for their preparation

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/725
  • C08B-037/10
출원번호 US-0357548 (1989-05-26)
우선권정보 IT-0003504 (1988-06-10)
발명자 / 주소
  • Piani Silvano (Bologna ITX) Tamagnone Gianfranco (Casafecchio di Reno ITX) Alpino Raul R. (Bologna ITX) Milani Maria R. (Trebbo di Reno ITX) Fantuz Marinella (Bologna ITX)
출원인 / 주소
  • Alfa Wasserman S.p.A. (Alanno Scalo ITX 03)
인용정보 피인용 횟수 : 42  인용 특허 : 3

초록

New heparin derivatives having antithrombotic activity, also endowed with reduced hemorrhagic and anticoagulant activity, obtained by treating in a basic medium heparins of various origin, optionally in the presence of alkali metal salts and of a reducing agent. The heparin derivatives obtained thro

대표청구항

A heparin derivative which exhibits signals in the 13C-NMR spectrum at about 53 and about 54 ppm, specific rotatory power [a20 between about +50°and about +90°in aqueous solution, sulfur content between about 8% and about 11% and sulfate/carboxyl ratio between about 1.50 and about 2.20. A process fo

이 특허에 인용된 특허 (3)

  1. Feller Wolfgang (Melsungen DEX) Strmer Rainer (Kassel DEX) Mller Annemarie (Knllwald-Niederbeisheim DEX), Heparin derivatives.
  2. Bianchini Pietro (Corlo ITX) Mascellani Giuseppe (Corlo ITX), Novel oligosaccharides having pharmacological properties by depolymerization of heparin.
  3. Bianchini Pietro (Corlo ITX) Mascellani Giuseppe (Corlo ITX), Oligosaccharides obtained by heparin depolymerization having antiatherosclerotic activity.

이 특허를 인용한 특허 (42)

  1. Kaundinya, Ganesh; Shriver, Zachary; Sundaram, Mallikarjun; Qi, Yi-wei; Sasisekharan, Ram, Analysis of sulfated polysaccharides.
  2. Venkataraman, Ganesh; Shriver, Zachary; Sundaram, Malikarjun; Qi, Yi Wei; Sasisekharan, Ram, Analysis of sulfated polysaccharides.
  3. Cahalon,Liora; Cohen,Irun R.; Lider,Ofer; Margalit,Raanan, Anti-cancer therapeutic compounds.
  4. van den Elzen, Peter; Brenner, Michael B., Apolipoprotein E as an adjuvant for lipid antigens.
  5. Hirsh Jack,CAX ; Weitz Jeffrey I.,CAX, Compositions and methods for inhibiting thrombogenesis.
  6. Weitz Jeffrey I.,CAX ; Hirsh Jack,CAX ; Young Edward,CAX, Compositions and methods for inhibiting thrombogenesis.
  7. Weitz Jeffrey I.,CAX ; Hirsh Jack,CAX ; Young Edward,CAX, Compositions and methods for inhibiting thrombogenesis.
  8. Cohen Irun R.,ILX ; Lider Ofer,ILX ; Cahalon Liora,ILX ; Shoseyov Oded,ILX ; Margalit Raanan,ILX, Compositions and methods for regulation of active TNF-.alpha..
  9. Cohen, Irun R.; Lider, Ofer; Cahalon, Liora; Shoseyov, Oded; Margalit, Raanan, Compositions for the regulation of cytokine activity.
  10. Cohen,Irun R.; Lider,Ofer; Cahalon,Liora; Shoseyov,Oded; Margalit,Raanan, Compositions for the regulation of cytokine activity.
  11. Beccati, Daniela; Capila, Ishan; Gunay, Nur Sibel; Roy, Sucharita, Evaluating heparin preparations.
  12. Gunay, Nur Sibel; Lech, Miroslaw; Roy, Sucharita; Schaeck, John; Ozug, Jennifer; Beccati, Daniela; Capila, Ishan, Evaluating heparin preparations.
  13. Liu,Dongfang; Pojasek,Kevin; Shriver,Zachary; Holley,Kristine; El Shabrawi,Yosuf; Venkataraman,Ganesh; Sasisekharan,Ram, Heparinase III and methods of specifically cleaving therewith.
  14. Liu, Dongfang; Pojasek, Kevin; Shriver, Zachary; Holley, Kristine; El-Shabrawi, Yosuf; Venkataraman, Ganesh; Sasisekharan, Ram, Heparinase III and uses thereof.
  15. Tuch,Ronald J., Medical device for delivering a therapeutic agent and method of preparation.
  16. Berg Eric P. ; Dinh Thomas Q., Medical device for delivering a therapeutic substance and method therefor.
  17. Berg, Eric P.; Dinh, Thomas Q., Medical device for delivering a therapeutic substance and method therefor.
  18. Thomas Q. Dinh ; Rodney G. Wolff ; Eric P. Berg, Medical device for delivering a therapeutic substance and method therefor.
  19. Dinh Thomas Q. ; Wolff Rodney G. ; Berg Eric P., Medical device for delivering a water-insoluble therapeutic salt or substance.
  20. Berg Eric P. ; Dinh Thomas Q., Medical device for delivering localized radiation.
  21. Berg, Eric P.; Tuch, Ronald J.; Dror, Michael; Wolff, Rodney G., Medical devices for delivering a therapeutic agent and method of preparation.
  22. Berg,Eric P.; Tuch,Ronald J.; Dror,Michael; Wolff,Rodney G., Medical devices for delivering a therapeutic agent and method of preparation.
  23. Venkataraman,Ganesh; Shriver,Zachary; Raman,Rahul; Sasisekharan,Ram; Keiser,Nishla, Method for analyzing polysaccharides.
  24. Venkataraman, Ganesh; Shriver, Zachary; Raman, Rahul; Sasisekharan, Ram; Keiser, Nishla, Method for identifying or characterizing properties of polymeric units.
  25. Venkataraman,Ganesh; Shriver,Zachary; Raman,Rahul; Sasisekharan,Ram; Keiser,Nishla, Method for identifying or characterizing properties of polymeric units.
  26. Venkataraman,Ganesh; Shriver,Zachary; Raman,Rahul; Sasisekharan,Ram; Keiser,Nishla, Method for identifying or characterizing properties of polymeric units.
  27. Venkataraman, Ganesh; Shriver, Zachary; Raman, Rahul; Sasisekharan, Ram; Keiser, Nishla, Method for indentifying or characterizing properties of polymeric units.
  28. Venkataraman,Ganesh; Shriver,Zachary; Raman,Rahul; Sasisekharan,Ram; Keiser,Nishla, Method for the compositional analysis of polymers.
  29. Shriver, Zachary; Bhatnagar, Naveen; Gunay, Nur Sibel; Ozug, Jennifer; Sun, Elaine Y., Method of analyzing a preparation of a low molecular weight heparin.
  30. Palazzini,Ernesto; Gambaro,Giovanni, Methods and compositions using sulodexide for the treatment of diabetic nephropathy.
  31. Sasisekharan, Ram; Venkataraman, Ganesh; Shriver, Zachary; Liu, Dongfang; Sundaram, Mallikarjun; Qi, Yiwei, Methods and producing low molecular weight heparin.
  32. Sasisekharan,Ram; Venkataraman,Ganesh; Shriver,Zachary; Liu,Dongfang; Sundaram,Mallikarjun; Qi,Yiwei, Methods and products related to evaluating the quality of a polysaccharide.
  33. Liu, Dongfang; Qi, Yiwei; Venkataraman, Ganesh; Sundaram, Mallikarjun; Sasisekharan, Ram, Methods and products related to pulmonary delivery of polysaccharides.
  34. Sasisekharan,Ram; Venkataraman,Ganesh; Shriver,Zachary; Liu,Dongfang; Sundaram,Mallikarjun; Qi,Yiwei, Methods and products related to the analysis of polysaccarides.
  35. Sasisekharan, Ram; Venkataraman, Ganesh; Shriver, Zachary; Liu, Dongfang; Sundaram, Mallikarjun; Qi, Yiwei, Methods for analyzing a heparin sample.
  36. Sasisekharan, Ram; Venkataraman, Ganesh; Shriver, Zachary; Liu, Dongfang; Sundaram, Mallikarjun; Qi, Yiwei, Methods for analyzing or processing a heparin sample.
  37. Sasisekharan, Ram; Venkataraman, Ganesh; Shriver, Zachary; Liu, Dongfang; Sundaram, Mallikarjun; Qi, Yiwei, Methods for evaluating the quality of a heparin sample.
  38. Liu,Dongfang; Pojasek,Kevin; Shriver,Zachary; Holley,Kristine; El Shabrawi,Yosuf; Venkataraman,Ganesh; Sasisekharan,Ram, Methods for preparing low molecular weight heparin with modified heparinase III.
  39. Cohen Irun R.,ILX ; Lider Ofer,ILX ; Cahalon Liora,ILX ; Shoseyov Oded,ILX ; Margalit Raanan,ILX, Methods for regulation of active TNF-.alpha..
  40. Sasisekharan,Ram; Shriver,Zachary; Liu,Dongfang; Venkataraman,Ganesh, Rationally designed heparinases derived from heparinase I and II.
  41. Sasisekharan, Ram; Shriver, Zachary; Liu, Dongfang; Venkataraman, Ganesh, Rationally designed heparinases derived from heparinase I and II and methods of sequencing therewith.
  42. Godavarti Ranganathan ; Sasisekharan Ram ; Ernst Steffen,DKX ; Venkataraman Ganesh ; Cooney Charles L. ; Langer Robert, Rationally designed polysaccharide lyases derived from heparinase I.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트