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Multiepitopic immunometric assay 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-005/00
  • G01N-033/53
  • G01N-033/545
  • C12Q-001/00
출원번호 US-0102766 (1987-09-24)
발명자 / 주소
  • Bellet Dominique (Paris MA FRX) Wands Jack R. (Waban MA)
출원인 / 주소
  • The General Hospital Corporation (Boston MA 02)
인용정보 피인용 횟수 : 201  인용 특허 : 8

초록 ▼

The invention relates to an immunometric assay for a multivalent antigen in a sample which comprises forming a complex of the antigen together with multiple immobilized monoclonal antibodies against different epitopes of the antigen and with a detectably labeled soluble monoclonal antibody which is

대표청구항 ▼

An immunometric assay for a multivalent antigen in a sample, comprising: (a) forming a mixture of said sample with multiple immobilized monoclonal antibodies against different epitopes on said antigen, and incubating said mixture for a time and under conditions sufficient to allow said antigen in sa

이 특허에 인용된 특허 (8)

  1. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
    상세보기
  2. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
    상세보기
  3. Newman Edward S. (Nutley NJ), Isolation of alpha1-fetoprotein.
    상세보기
  4. Smith William L. (Okemos MI) DeWitt David L. (East Lansing MI), Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies.
    상세보기
  5. Khazaeli Mohammad B. (Ann Arbor MI) Beierwaltes William H. (Ann Arbor MI) England Barry G. (Ann Arbor MI), Monoclonal antibodies specific for the unbound b 상세보기
  • Canfield Robert E. (New York NY) Ehrlich Paul H. (New York NY) Moyle William R. (Piscataway NJ), Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays.
    상세보기
  • Remington Jack S. (Palo Alto CA) Araujo Fausto G. (Palo Alto CA), Sandwich immunoassay and compositions for use therein.
    상세보기
  • Murad Ferid (Los Altos Hills CA) Lewicki John A. (San Jose CA), Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same.
    상세보기

    • 이 특허를 인용한 특허 (201)

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