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System and method for transdermal drug delivery

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
  • A61K-013/02
출원번호 US-0355718 (1989-05-22)
발명자 / 주소
  • Katz Martin (Menlo Park CA) Nacht Sergio (Los Altos CA) Heller Jorge (Woodside CA)
출원인 / 주소
  • Advanced Polymer Systems, Inc. (Redwood City CA 02)
인용정보 피인용 횟수 : 67  인용 특허 : 2

초록

Transdermal drug delivery systems comprise a backing or enclosure having a matrix layer which incorporates a drug and a percutaneous enhancer for the drug. The percutaneous enhancer and/or drug will be contained within polymeric particles dispersed through the matrix layer, where the polymeric parti

대표청구항

A device for the rate-controlled delivery of a drug, said device comprising: a matrix layer; means for mechanically supporting the matrix layer; a drug within the matrix layer; and a plurality of polymeric particles dispersed in the matrix layer, said particles each defining a network of internal po

이 특허에 인용된 특허 (2)

  1. Lipshitz Harold M. (Carlisle MA), Controlled topical application of bioactive reagent.
  2. Nuwayser Elie S. (Wellesley MA), Transdermal drug delivery system.

이 특허를 인용한 특허 (67)

  1. Radloff, Detlev; Wasner, Matthias, Active substance patch, kind to the skin, for transdermal administration of nonsteroidal antirheumatics.
  2. Glenn,Gregory M.; Alving,Carl R., Adjuvant for transcutaneous immunization.
  3. Fossel, Eric T., Beneficial effects of increasing local blood flow.
  4. Ng, Steven Y.; Heller, Jorge, Bioerodible poly (orthoesters) from dioxolane-based diketene acetals.
  5. Ng, Steven Y.; Heller, Jorge, Block copolymers based on poly(ortho esters) containing amine groups.
  6. Wang, Shiping; Yeh, Yun-Siung Tony; Owens, James; Wong, Wei Cheong, Coating composition for skin-contacting surface of elastomeric articles and articles containing the same.
  7. Hale Ron L. (Woodside CA) Lu Amy (Los Altos CA) Solas Dennis (San Francisco CA) Selick Harold E. (Belmont CA) Oldenburg Kevin R. (Fremont CA) Zaffaroni Alejandro C. (Atherton CA), Compositions and methods for enhanced drug delivery.
  8. Sirkar Kamalesh K. ; Farrell Stephanie ; Basu Rahul, Controlled release device and method based on aqueous--organic partitioning in porous membranes.
  9. Sirkar Kamalesh K. ; Farrell Stephanie ; Basu Rahul, Controlled release device based on aqueous-organic partitioning in porous membranes.
  10. Brocchini,Stephen J.; Heller,Jorge; Tomlinson,Ryan; Duncan,Ruth; Garrett,Shane; Klee,Marcus M., Degradable polyacetal polymers.
  11. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  12. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  13. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  14. DeVillez Richard L. ; Crane Laura J., Device for delivery of dermatological ingredients.
  15. Bruder, Mark H.; Ingram, Aaron N., Eye treatment compress.
  16. Scher Herbert B. (Moraga CA) Rodson Marius (El Sobrante CA), Impregnated porous granules and a polyurethane matrix held within the pores thereof and holding a liquid material for co.
  17. Chou, Kang-Jye; Guo, Hong; Ashton, Paul; Shimizu, Robert W.; Watson, David A., Injectable sustained release delivery devices.
  18. Grawe, Detlef; Hoesel, Peter; Fischer, Wilfried, Laminates containing an active substance transdermal system.
  19. Hyunjo Kim ; Reza Fassihi, Matrix for controlled delivery of highly soluble pharmaceutical agents.
  20. Schwarz, Franz Xaver; Szerdi, Szabolcs, Method and device for oral application of a composition.
  21. Ashton, Paul, Method for treating and/or preventing retinal diseases with sustained release corticosteroids.
  22. Reder, Robert F.; Goldenheim, Paul D.; Kaiko, Robert F., Method of providing sustained analgesia with buprenorphine.
  23. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
  24. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorphine.
  25. Reder, Robert F.; Kaiko, Robert F.; Goldenheim, Paul D., Method of providing sustained analgesia with buprenorpine.
  26. Bruder, Mark H.; Ingram, Aaron N., Moist heat therapy compress.
  27. D'Angelo Joseph P. ; Schur Henry, Multidose transdermal drug delivery system.
  28. Gueret, Jean-Louis, Patch, a kit constituted by a patch and a receptacle and a method.
  29. Ninomiya Kazuhisa,JPX ; Tokuda Shoichi,JPX ; Fukushima Yasuhiro,JPX, Percutaneous absorption preparation.
  30. Iga,Katsumi; Suzuki,Yasuyuki; Naka,Takehiko, Percutaneous absorption preparation of compound having angiotensin II antagonistic activity.
  31. Marchitto, Kevin S.; Flock, Stephen T., Remote and local controlled delivery of pharmaceutical compounds using electromagnetic energy.
  32. Sylvia Rossi-Montero ; Juan Mantelle ; David Kanios ; David Houze, Solubility enhancement of drugs in transdermal drug delivery systems and methods of use.
  33. Chen Jianbing ; Ashton Paul, Sustained release drug delivery devices.
  34. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  35. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  36. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  37. Guo, Hong; Ashton, Paul, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  38. Hong Guo ; Paul Ashton, Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof.
  39. Fossel, Eric T., Systems and methods for treatment of allergies and other indications.
  40. Bruder, Mark H., Therapeutic eye mask.
  41. Wright, IV, Curtis, Titratable dosage transdermal delivery system.
  42. Wright, IV, Curtis, Titratable dosage transdermal delivery system.
  43. Fossel, Eric T., Topical composition containing ibuprofen.
  44. Fossel, Eric T., Topical composition containing naproxen.
  45. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  46. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  47. Glenn, Gregory M.; Alving, Carl R., Transcutaneous immunization without heterologous adjuvant.
  48. Barnhart Scott D. ; Mariani Elio P., Transdermal delivery of active drugs.
  49. Fossel, Eric Thor, Transdermal delivery of beneficial substances effected by a hostile biophysical environment.
  50. Rosenbaum Jerry, Transdermal delivery of dehydroepiandrosterone.
  51. Ribeiro Dos Santos, Isabel; Sournac, Michel, Transdermal device including porous microparticles.
  52. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  53. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  54. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  55. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  56. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  57. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  58. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  59. Hsu Tsung-Min ; Chen Tung Fen, Two-phase matrix for sustained release drug delivery device.
  60. Glenn, Gregory M.; Alving, Carl R., Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response.
  61. Glenn,Gregory M.; Alving,Carl R., Use of penetration enhancers and barrier disruption methods to enhance the immune response of antigen and adjuvant.
  62. Glenn, Gregory M.; Cassels, Frederick J., Vaccine for transcutaneous immunization.
  63. Bruder, Mark H.; Ingram, Aaron N., Wound and therapy compress and dressing.
  64. Bruder, Mark H.; Ingram, Aaron N., Wound and therapy compress and dressing.
  65. Bruder, Mark H.; Ingram, Aaron N., Wound and therapy compress and dressing.
  66. Bruder, Mark H.; Ingram, Aaron N., Wound and therapy compress and dressing.
  67. Bruder, Mark H.; Ingram, Aaron N., Wound and therapy compress and dressing.
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