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Blood substitutes 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-037/14
  • C07K-013/00
출원번호 US-0194338 (1988-05-16)
우선권정보 GB-0011614 (1987-05-16)
발명자 / 주소
  • Hoffman Stephen L. (Denver CO) Nagai Kiyoshi (Cambridge GB2)
출원인 / 주소
  • Somatogenetics International, Inc. (Broomfield CO 02)
인용정보 피인용 횟수 : 99  인용 특허 : 1

초록 ▼

Solutions of mutant hemoglobins having a lower oxygen affinity than that of native hemoglobin are used as blood substitutes. The mutant hemoglobins are preferably obtained by recombinant DNA techniques. Both alpha and beta globin chains can now be so prepared, making possible the production of wholl

대표청구항

A method of supplementing the oxygen-carrying capacity of a patient\s blood which comprises administering to the patient a nontoxic composition comprising a cell-free mutant hemoglobin.

이 특허에 인용된 특허 (1)

  1. Tye Ross W. (937 B Rosenstock Rd. Sausalito CA 94965), Modified crosslinked stroma-free tetrameric hemoglobin.
    상세보기

이 특허를 인용한 특허 (99)

  1. Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
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  2. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  3. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  4. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  5. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis J.; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  6. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis J.; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  7. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  8. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Schein, Douglas; Harris, Stanley; Steibel, Dennis; Fraser, Richard; Isaacs, Dickon, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  9. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Schein, Douglas; Isaacs, Dickon, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
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