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Novel heparin derivatives 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-033/34
  • A61K-033/32
출원번호 US-0306020 (1989-01-27)
우선권정보 SE-0002254 (1987-05-27)
국제출원번호 PCT/SE88/00282
§371/§102 date 19890127 (19890127)
국제공개번호 WO-8809347 (1988-12-01)
발명자 / 주소
  • Bergendal Karin H. L. (Danderyd SEX) Johansson Rolf A. (Huddinge SEX) Svahn Carl M. E. (Sollentuna SEX)
출원인 / 주소
  • KabiVitrum AB (Stockholm SEX 03)
인용정보 피인용 횟수 : 63  인용 특허 : 0

초록

A novel complex of (a) a metal ion selected from copper, calcium, manganese, iron, and zinc ions, and (b) a fraction of heparin, heparan sulfate, low molecular weight heparin, low molecular weight heparan sulfate, heparin fragments, heparan sulfate fragments, and oligosaccharides derived from hepari

대표청구항

A novel complex of (a) a metal ion selected from copper, calcium, manganese, iron, and zinc ions, and (b) a fraction of heparin, heparan sulfate, low molecular weight heparin, low molecular weight heparan sulfate, heparin fragments, heparan sulfate fragments, and oligosaccharides derived from hepari

이 특허를 인용한 특허 (63)

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  13. Liu,Dongfang; Pojasek,Kevin; Shriver,Zachary; Holley,Kristine; El Shabrawi,Yosuf; Venkataraman,Ganesh; Sasisekharan,Ram, Heparinase III and methods of specifically cleaving therewith.
  14. Liu, Dongfang; Pojasek, Kevin; Shriver, Zachary; Holley, Kristine; El-Shabrawi, Yosuf; Venkataraman, Ganesh; Sasisekharan, Ram, Heparinase III and uses thereof.
  15. Ranney David F., In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and k.
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  20. Dinh Thomas Q. ; Wolff Rodney G. ; Berg Eric P., Medical device for delivering a water-insoluble therapeutic salt or substance.
  21. Berg Eric P. ; Dinh Thomas Q., Medical device for delivering localized radiation.
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  26. Viskov, Christian; Mourier, Pierre, Method for determining specific groups constituting heparins or low molecular weight heparins.
  27. Venkataraman, Ganesh; Shriver, Zachary; Raman, Rahul; Sasisekharan, Ram; Keiser, Nishla, Method for identifying or characterizing properties of polymeric units.
  28. Venkataraman,Ganesh; Shriver,Zachary; Raman,Rahul; Sasisekharan,Ram; Keiser,Nishla, Method for identifying or characterizing properties of polymeric units.
  29. Venkataraman,Ganesh; Shriver,Zachary; Raman,Rahul; Sasisekharan,Ram; Keiser,Nishla, Method for identifying or characterizing properties of polymeric units.
  30. Venkataraman, Ganesh; Shriver, Zachary; Raman, Rahul; Sasisekharan, Ram; Keiser, Nishla, Method for indentifying or characterizing properties of polymeric units.
  31. Venkataraman,Ganesh; Shriver,Zachary; Raman,Rahul; Sasisekharan,Ram; Keiser,Nishla, Method for the compositional analysis of polymers.
  32. Shriver, Zachary; Bhatnagar, Naveen; Gunay, Nur Sibel; Ozug, Jennifer; Sun, Elaine Y., Method of analyzing a preparation of a low molecular weight heparin.
  33. Zasloff Michael ; Shinnar Ann ; Kinney William ; Anderson Mark ; Williams Jon ; McLane Michael, Method of inhibiting profileration of cells by administering an aminosterol compound.
  34. Zasloff Michael ; Shinnar Ann ; Kinney William ; Rao Meena, Method of inhibiting proliferation of cells by administering an aminosterol compound.
  35. Zasloff Michael, Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine.
  36. Zasloff Michael, Method of treating a viral infection by administering a steroid compound.
  37. Sasisekharan, Ram; Venkataraman, Ganesh; Shriver, Zachary; Liu, Dongfang; Sundaram, Mallikarjun; Qi, Yiwei, Methods and producing low molecular weight heparin.
  38. Sasisekharan,Ram; Venkataraman,Ganesh; Shriver,Zachary; Liu,Dongfang; Sundaram,Mallikarjun; Qi,Yiwei, Methods and products related to evaluating the quality of a polysaccharide.
  39. Liu, Dongfang; Qi, Yiwei; Venkataraman, Ganesh; Sundaram, Mallikarjun; Sasisekharan, Ram, Methods and products related to pulmonary delivery of polysaccharides.
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  44. Hahn, Gary S.; Thueson, David O., Methods for inhibiting sensory nerves by topically administering strontium-containing compositions to keratinized skin.
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  55. Kinney, William A.; Zhang, Xuehai; Michalak, Ronald, Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols.
  56. Kinney, William A.; Zhang, Xuehai; Michalak, Ronald, Regioselective and stereoselective oxidation of fused ring systems useful for the preparation of aminosterols.
  57. Alan D. Snow, Rodent models of human amyloidoses.
  58. Kinney William A. ; Jones Steven ; Zhang Xuehai ; Rao Meena N. ; Bulliard Michel,FRX ; Meckler Harold ; Lee Nancy, Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds.
  59. Kinney, William A.; Jones, Steven; Zhang, Xuehai; Rao, Meena N.; Bulliard, Michel; Meckler, Harold; Lee, Nancy, Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds.
  60. Zasloff Michael, Therapeutic uses for an aminosterol compound.
  61. Hahn,Gary S.; Thueson,David O., Topical product formulations containing strontium for reducing skin irritation.
  62. Zasloff Michael ; Williams Jon, Treatment of carcinomas using squalamine in combination with other anti-cancer agents.
  63. Zasloff, Michael; Williams, Jon; Sokoloff, Mitchell H., Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities.
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