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Method of potentiating an immune response 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/56
  • A61K-039/085
  • A61K-039/35
  • A61K-045/05
출원번호 US-0169973 (1988-03-18)
발명자 / 주소
  • Tice Thomas R. (Birmingham AL) Gilley Richard M. (Birmingham AL) Eldridge John H. (Birmingham AL) Staas Jay K. (Birmingham AL) Hollingshead Melinda G. (Birmingham AL) Shannon William M. (Birmingham A
출원인 / 주소
  • Southern Research Institute (Birmingham AL 02) UAB Research Foundation (Birmingham AL 02)
인용정보 피인용 횟수 : 246  인용 특허 : 0

초록

A method of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size ranging from between approximately one micrometer to approximately ten micrometers and admnistering effective amo

대표청구항

A method of potentiating the immune response of an animal, comprising the step of parenterally administering to said animal a mixture of effective amounts of first biocompatible microcapsules having a size between approximately 1 micrometer and approximately 10 micrometers and containing a bioactive

이 특허를 인용한 특허 (246)

  1. Jevanthi,Ramasubbu; Van Hamont,John E.; Friden,Phil; Reid,Robert H.; Roberts,F. Donald; McQueen,Charles E.; Setterstrom,Jean A., "Burst-free" sustained release poly-(lactide/glycolide) microspheres.
  2. Condon, Stephen M.; Deng, Yijun; Laporte, Matthew G.; Rippin, Susan R., 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic.
  3. David A. Edwards ; Giovanni Caponetti ; Jeffrey S. Hrkach ; Noah Lotan IL; Justin Hanes ; Abdellaziz Ben-Jebria ; Robert S. Langer, Aerodynamically light particles for pulmonary drug delivery.
  4. Edwards David A. ; Caponetti Giovanni,ITX ; Hrkach Jeffrey S. ; Lotan Noah,ILX ; Hanes Justin ; Ben-Jebria Abdell Aziz ; Langer Robert S., Aerodynamically light particles for pulmonary drug delivery.
  5. Edwards, David A.; Caponetti, Giovanni; Hrkach, Jeffrey S.; Lotan, Noah; Hanes, Justin; Ben-Jebria, Abdellaziz; Langer, Robert S., Aerodynamically light particles for pulmonary drug delivery.
  6. Edwards, David A.; Caponetti, Giovanni; Hrkach, Jeffrey S.; Lotan, Noah; Hanes, Justin; Ben-Jebria, Abdellaziz; Langer, Robert S., Aerodynamically light particles for pulmonary drug delivery.
  7. Dervan, Peter B.; Briehn, Christoph A.; Renneberg, Dorte; Weyermann, Philipp; Doss, Raymond; Marques, Michael, Alternative heterocycles for DNA recognition.
  8. Orentas, Rimas J.; Mackall, Crystal L.; Pastan, Ira H., Anti-CD22 chimeric antigen receptors.
  9. Aoyagi, Teikichi; Luo, Peter Peizhi; Zhong, Pingyu; Hsieh, Mark; Li, Yan; Wang, Kevin Caili; Morimoto, Chikao, Anti-CD26 antibodies and methods of use thereof.
  10. Aoyagi,Teikichi; Luo,Peter Peizhi; Zhong,Pingyu; Hsieh,Mark; Li,Yan; Wang,Kevin Caili; Morimoto,Chikao, Anti-CD26 antibodies and methods of use thereof.
  11. Wong, Chi-Huey; Wu, Chung-Yi, Anti-HER2 glycoantibodies and uses thereof.
  12. Slack, Frank J.; Boehm, Michelle M., Anti-aging micrornas.
  13. Morgan, Richard A.; Rosenberg, Steven A., Anti-epidermal growth factor receptor variant III chimeric antigen receptors and use of same for the treatment of cancer.
  14. Morgan, Richard A.; Rosenberg, Steven A., Anti-epidermal growth factor receptor variant III chimeric antigen receptors and use of same for the treatment of cancer.
  15. Rader, Christoph; Baskar, Sivasubramanian, Anti-human ROR1 antibodies.
  16. Feldman, Steven A.; Rosenberg, Steven A.; Pastan, Ira H., Anti-mesothelin chimeric antigen receptors.
  17. Rosenberg, Steven A.; Chinnasamy, Dhanalakshmi, Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer.
  18. Rosenberg, Steven A.; Chinnasamy, Dhanalakshmi, Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer.
  19. Rosenberg, Steven A.; Chinnasamy, Dhanalakshmi, Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer.
  20. Rosenthal, Arnon; Pons, Jaume; Ho, Wei-Hsien, Antibodies directed against amyloid-beta peptide and methods using same.
  21. Rosenthal, Arnon; Pons, Jaume; Ho, Wei-Hsien; Grimm, Jan Markus, Antibodies directed against amyloid-beta peptide and methods using same.
  22. Rosenthal, Arnon; Pons, Jaume; Ho, Wei-Hsien, Antibodies directed against amyloid-beta peptide and nucleic acids encoding same.
  23. Carlsson, Hans; Larsson, Anette; S?derlind, Erik, Antigen delivery system and method of production.
  24. Clark, Fred M.; Offit, Paul A.; Speaker, Tully J., Aqueous solven encapsulation method, apparatus and microcapsules.
  25. Rader, Christoph; Baskar, Sivasubramanian; Bishop, Michael R.; Samija, Ivan; Suschak, Jessica M., B cell surface reactive antibodies.
  26. Grosmaire, Laura Sue; Hayden-Ledbetter, Martha Susan; Ledbetter, Jeffrey A.; Thompson, Peter Armstrong; Simon, Sandy Alexander; Brady, William, B-cell reduction using CD37-specific and CD20-specific binding molecules.
  27. Ledbetter, Jeffrey A.; Hayden-Ledbetter, Martha, Binding domain-immunoglobulin fusion proteins.
  28. Pun, Suzie H.; Chan, Leslie; White, Nathan J., Biocompatible polymeric system for targeted treatment of thrombotic and hemostatic disorders.
  29. Kiser, Patrick F.; Thomas, Allen A., Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments.
  30. Van Nest, Gary; Tuck, Stephen; Fearon, Karen L.; Dina, Dino, Biodegradable immunomodulatory formulations and methods for use thereof.
  31. Berde Charles B. (Brookline MA) Langer Robert S. (Newton MA), Biodegradable polymer matrices for sustained delivery of local anesthetic agents.
  32. Berde Charles B. ; Langer Robert S., Biodegradable polymer matrices for sustained delivery of local anesthetic agents.
  33. Tan, Philip; Simon, Sandy A; Cerveny, Charles G; Nilsson, Christy Anne; Brady, William; Ledbetter, Jeffrey A; Hayden-Ledbetter, Martha S; Thompson, Peter A; Morales, Cecile, CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof.
  34. Myc, Andrzej; Kryczek, Ilona; Baker, Jr., James R., Cancer vaccine compositions and methods of using the same.
  35. Wong, Chi-Huey; Fang, Jim-Min; Cheng, Yih-Shyun E.; Tsai, Chamg-Sheng, Cell-permeable probes for identification and imaging of sialidases.
  36. Jean A. Setterstrom ; Elliot Jacob ; Thomas R. Tice, Chemotherapeutic treatment of bacterial infections with an antibiotic encapsulated within a biodegradable polymeric matrix.
  37. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Composition for delivering bioactive agents for immune response and its preparation.
  38. Hatchwell, Eli; Eis, Peggy S., Compositions and methods for discovery of causative mutations in genetic disorders.
  39. Stock, Jeffry B.; Stock, Maxwell; Gu, Haoming; Stock, Gregory B; Li, Zhu; Wolanin, Peter Michael, Compositions and methods for enhancing cognitive function.
  40. Holoshitz, Joseph; Ling, Song; Pi, Xiujun; de Almeida, Denise; Gilon, Chaim; Hoffman, Amnon, Compositions and methods for inducing an immune response.
  41. Holoshitz, Joseph; Ling, Song; Pi, Xiujun; de Almeida, Denise; Gilon, Chaim; Hoffman, Amnon, Compositions and methods for inducing an immune response.
  42. Childs, Richard William Wyatt; Takahashi, Yoshiyuki; Kajigaya, Sachiko; Harashima, Nanae, Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject.
  43. Childs, Richard William Wyatt; Takahashi, Yoshiyuki; Kajigaya, Sachiko; Harashima, Nanae, Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject.
  44. Ben-Eliyahu, Shamgar; Matzner, Pini; Reed, Steven G., Compositions and methods for reducing or preventing metastasis.
  45. Yan, Xinhua; Morgan, James P.; Cantley, Lewis C., Compositions and methods for treating or preventing anthracycline induced cardiotoxicity.
  46. Feener, Edward P.; Aiello, Lloyd P., Compositions and methods for treating vascular permeability.
  47. Wong, Chi-Huey; Hsu, Tsui-Ling; Lou, Yi-Wei; Lin, Chih-Wei; Yeh, Shih-Chi; Wu, Chung-Yi; Wu, Han-Chung, Compositions and methods for treatment and detection of cancers.
  48. Wong, Chi-Huey; Hsu, Tsui-Ling; Lou, Yi-Wei; Lin, Chih-Wei; Yeh, Shih-Chi; Wu, Chung-Yi; Wu, Han-Chung, Compositions and methods for treatment and detection of cancers.
  49. Wong, Chi-Huey; Hsu, Tsui-Ling; Lou, Yi-Wei; Lin, Chih-Wei; Yeh, Shih-Chi; Wu, Chung-Yi; Wu, Han-Chung, Compositions and methods for treatment and detection of cancers.
  50. Wong, Chi-Huey; Wu, Chung-Yi; Ma, Che, Compositions and methods relating to universal glycoforms for enhanced antibody efficacy.
  51. Wong, Chi-Huey; Wu, Chung-Yi; Ma, Che; Wu, Han-Chung, Compositions and methods relating to universal glycoforms for enhanced antibody efficacy.
  52. Das Gupta, Tapas; Chakrabarty, Ananda, Compositions and methods to prevent cancer with cupredoxins.
  53. Gupta, Tapas Das; Chakrabarty, Ananda, Compositions and methods to prevent cancer with cupredoxins.
  54. Kahre, Olev; Artma, Kadri; Kahre, Tiina, Compositions for increasing polypeptide stability and activity, and related methods.
  55. Cleland, Jeffrey L.; Lim, Amy; Powell, Michael Frank, Compositions for microencapsulation of antigens for use as vaccines.
  56. Kaplan, Lee M.; Liou, Alice P.; Turnbaugh, Peter J.; Harris, Jason L., Compositions of microbiota and methods related thereto.
  57. Eldridge, Gary R., Compounds, compositions and methods for controlling biofilms and bacterial infections.
  58. Brunham,Robert C., DNA immunization againstinfection.
  59. Dervan, Peter B.; Foister, Shane; Doss, Raymond; Marques, Michael A., DNA-binding polymers.
  60. Dervan,Peter B.; Foister,Shane; Doss,Raymond; Marques,Michael A., DNA-binding polymers.
  61. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakis, Nick, Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes.
  62. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakls, Nick, Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes.
  63. Bamdad, Cynthia C., Diagnostic tumor markers, drug screening for tumorigenesis inhibition, and compositions and methods for treatment of cancer.
  64. Bamdad, Cynthia C.; Bamdad, R. Shoshana, Diagnostic tumor markers, drug screening for tumorigenesis inhibition, and compositions and methods for treatment of cancer.
  65. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippen, Susan R., Dimeric IAP inhibitors.
  66. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippin, Susan R., Dimeric IAP inhibitors.
  67. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippin, Susan R., Dimeric IAP inhibitors.
  68. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippin, Susan R., Dimeric IAP inhibitors.
  69. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippin, Susan R., Dimeric IAP inhibitors.
  70. Condon, Stephen M.; Laporte, Matthew G.; Deng, Yijun; Rippin, Susan R., Dimeric IAP inhibitors.
  71. Condon, Stephen M.; Laporte, Matthew G.; Deng, Yijun; Rippin, Susan R., Dimeric IAP inhibitors.
  72. Xu, Feng, Drug conjugates and methods of use thereof.
  73. Farrar Graham Henry,GBX ; Tinsley-Bown Anne Margaret,GBX ; Jones David Hugh,CAX, Encapsulation of bioactive agents.
  74. Farrar, Graham Henry; Tinsley-Bown, Anne Margaret; Jones, David Hughes, Encapsulation of bioactive agents.
  75. Graham Henry Farrar GB; Anne Margaret Tinsley-Brown GB; David Hugh Jones CA, Encapsulation of bioactive agents.
  76. Wong, Chi-Huey; Fang, Jim-Min; Liu, Kung-Cheng; Jan, Jia-Tsrong; Cheng, Yih-Shyun E.; Cheng, Ting-Jen R., Enhanced anti-influenza agents conjugated with anti-inflammatory activity.
  77. Chinitz, James; Hatchwell, Eli; Roohi, Jasmin, Evaluating genetic disorders.
  78. Charles D. Y. Sia CA; Shi Xian Cao CA; Roy Persson CA; Benjamin Rovinski CA, Expressing gp140 fragment of primary HIV-1 isolate.
  79. Lipp, Michael W.; Batycky, Richard P.; Caponetti, Giovanni, Formulation for spray-drying large porous particles.
  80. Berde Charles B. ; Langer Robert S. ; Curley Joanne ; Castillo Jenny, Formulations and methods for providing prolonged local anesthesia.
  81. Charles B. Berde ; Robert S. Langer ; Joanne Curley ; Jenny Castillo, Formulations and methods for providing prolonged local anesthesia.
  82. Chasin Mark ; Sackler Richard ; Burch Ronald M. ; Goldenheim Paul ; Tigner Joseph, Formulations and methods for providing prolonged local anesthesia.
  83. Chasin, Mark; Goldenheim, Paul; Sackler, Richard; Tigner, Joseph; Burch, Ronald M, Formulations and methods for providing prolonged local anesthesia.
  84. Chasin, Mark; Sackler, Richard; Burch, Ronald M.; Goldenheim, Paul; Tigner, Joseph, Formulations and methods for providing prolonged local anesthesia.
  85. Chasin, Mark; Sackler, Richard; Burch, Ronald M.; Goldenheim, Paul; Tigner, Joseph, Formulations and methods for providing prolonged local anesthesia.
  86. Rader, Christoph; Kwong, Ka Yin, Fully human anti-human NKG2D monoclonal antibodies.
  87. Xu, Feng, GABA conjugates and methods of use thereof.
  88. Paya Cuenca, Carlos V.; Ter Meulen, Jan Henrik, GLA monotherapy for use in cancer treatment.
  89. Paya Cuenca, Carlos V.; Ter Meulen, Jan Henrik, GLA monotherapy for use in cancer treatment.
  90. Wong, Chi-Huey; Wu, Chung-Yi; Wang, Chia-Hung; Li, Shiou-Ting, Glycan conjugates and use thereof.
  91. Berde Charles B. ; Langer Robert S. ; Curley Joanne ; Castillo Jenny, High load formulations and methods for providing prolonged local anesthesia.
  92. Berde Charles B. ; Langer Robert S. ; Curley Joanne ; Castillo Jenny, High load formulations and methods for providing prolonged local anesthesia.
  93. Wong, Chi-Huey; Yu, Alice L.; Lin, Kun-Hsien; Wu, Tai-Na, Human iNKT cell activation using glycolipids.
  94. Wong, Chi-Huey; Yu, Alice L.; Lin, Kun-Hsien; Wu, Tai-Na, Human iNKT cell activation using glycolipids with altered glycosyl groups.
  95. Wong, Chi-Huey; Yu, Alice L.; Lin, Kun-Hsien; Wu, Tai-Na, Human iNKT cell activation using glycolipids with altered glycosyl groups.
  96. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippin, Susan R., IAP binding compounds.
  97. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippin, Susan R., IAP binding compounds.
  98. Condon, Stephen M.; Laporte, Matthew G.; Deng, Yijun; Rippin, Susan R., IAP binding compounds.
  99. Condon, Stephen M.; Laporte, Matthew G.; Deng, Yijun; Rippin, Susan R., IAP binding compounds.
  100. Condon,Stephen M.; LaPorte,Matthew G.; Deng,Yijun; Rippin,Susan R., IAP binding compounds.
  101. Condon, Stephen M.; LaPorte, Matthew G.; Deng, Yijun; Rippin, Susan R., IAP inhibitors.
  102. Lipford, Grayson B.; Zepp, Charles M., Imidazole quinoline-based immune system modulators.
  103. Lipford, Grayson B.; Zepp, Charles M., Immune system modulators.
  104. Lipford, Grayson B.; Zepp, Charles M., Immune system modulators.
  105. Lipford, Grayson B.; Zepp, Charles M., Immune system modulators.
  106. Lipford, Grayson B.; Zepp, Charles M., Immune system modulators.
  107. Lipford, Grayson B.; Zepp, Charles M., Immune system modulators.
  108. Dubensky, Jr., Thomas W.; Robbins, Scott H., Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses.
  109. Murdin, Andrew D.; Dunn, Pamela L., Immunogenic compositions for protection against chlamydial infection.
  110. Urban Robert G. ; Chicz Roman M. ; Collins Edward J. ; Hedley Mary Lynne, Immunogenic peptides from the HPV E7 protein.
  111. Urban Robert G. ; Chicz Roman M. ; Collins Edward J. ; Hedley Mary Lynne, Immunogenic peptides from the HPV E7 protein.
  112. Urban, Robert G.; Chicz, Roman M.; Collins, Edward J.; Hedley, Mary Lynne, Immunogenic peptides from the HPV E7 protein.
  113. Urban,Robert G.; Chicz,Roman M.; Collins,Edward J.; Hedley,Mary Lynne, Immunogenic peptides from the HPV E7 protein.
  114. Krieg, Arthur M.; Klinman, Dennis; Steinberg, Alfred D., Immunomodulatory oligonucleotides.
  115. Krieg, Arthur M.; Kline, Joel N.; Klinman, Dennis; Steinberg, Alfred D., Immunostimulatory nucleic acid molecules.
  116. Krieg, Arthur M.; Kline, Joel; Klinman, Dennis; Steinberg, Alfred D., Immunostimulatory nucleic acid molecules.
  117. Krieg, Arthur M.; Kline, Joel; Klinman, Dennis; Steinberg, Alfred D., Immunostimulatory nucleic acid molecules.
  118. Krieg, Arthur M.; Klinman, Dennis; Steinberg, Alfred D., Immunostimulatory nucleic acid molecules.
  119. Krieg, Arthur M.; Klinman, Dennis; Steinberg, Alfred D., Immunostimulatory nucleic acid molecules.
  120. Munnes, Marc; Weiss, Christian; Feldhues, Elisabeth; Schauer, Romina G.; Abraham, Albert; Eicker, Andrea; Wehlmann, Hermann, Immunostimulatory plasmids.
  121. Eldridge, Gary R., Inhibition of biofilm formation.
  122. Eldridge, Gary R.; Buckle, Ronald Neil; Ellis, Michael; Huang, Zhongping; Reilly, John Edward, Inhibitors of bacterial biofilms and related methods.
  123. Xu, Aimin; Wang, Yu; Lam, Karen S. L., Lipocalin-2 antibodies for methods of treatment.
  124. Orentas, Rimas J.; Pastan, Ira H.; Dimitrov, Dimiter S.; Mackall, Crystal L., M971 chimeric antigen receptors.
  125. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D., Macromolecular microparticles and methods of production and use.
  126. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D., Macromolecular microparticles and methods of production and use.
  127. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J., Macromolecular microparticles and methods of production and use.
  128. Owen, Charles F., Mast cell stabilizers to prevent or treat laminitis.
  129. Owen, Charles F., Mast cell stabilizers to prevent or treat laminitis.
  130. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissue and controlling their r.
  131. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissues and controlling their.
  132. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissues and controlling their.
  133. Cleland Jeffrey L. ; Jones Andrew J. S. ; Powell Michael Frank, Method for drying microspheres.
  134. Mathiowitz Edith ; Jong Yong S. ; Carino Gerardo ; Jacob Jules S., Method for gene therapy using nucleic acid loaded polymeric microparticles.
  135. Mathiowitz, Edith; Jong, Yong S.; Carino, Gerardo; Jacob, Jules S., Method for gene therapy using nucleic acid loaded polymeric microparticles.
  136. Ando Shuicho ; Putnam David ; Langer Robert S., Method for high supercoiled DNA content microspheres.
  137. Larsen, Janus Beierholm, Method for immunizing an avian species.
  138. Larsen, Janus Beierholm, Method for immunizing an avian species.
  139. Brayden,David J., Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof.
  140. Tice Thomas R. ; Gilley Richard M. ; Eldridge John H. ; Staas Jay K., Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor.
  141. Stock, Gregory; Stock, Jeffry B.; Stock, Maxwell; Vafai, Scott, Method of identifying modulators of PP2A methylase.
  142. Davis,Heather L.; Schorr,Joachim; Krieg,Arthur M., Method of inducing an antigen-specific immune response by administering a synergistic combination of adjuvants comprising unmethylated CpG-containing nucleic acids and a non-nucleic acid adjuvant.
  143. Mesens Jean (Wechelderzande BEX) Rickey Michael E. (Loveland OH) Atkins Thomas J. (Cincinnati OH), Method of inhibiting neurotransmitter activity using microencapsulated 3-piperidiny2-substituted 1,2-benzisoxazoles and.
  144. Jones David Hugh,GBX ; Farrar Graham Henry,GBX ; Clegg James Christopher Stephen,GBX, Method of making microencapsulated DNA for vaccination and gene therapy.
  145. Jones, David Hugh; Farrar, Graham Henry; Clegg, James Christopher Stephen, Method of making microencapsulated DNA for vaccination and gene therapy.
  146. Bowersock,Terry L.; Guimond,Paul; Ju,Tzu Chi R.; Kidane,Argaw, Method of vaccinating vertebrates.
  147. Hatchwell, Eli; Eis, Peggy S.; Scherer, Stephen; Prasad, Aparna, Methods and compositions for screening and treating developmental disorders.
  148. Kahne, Suzanne Walker; Swoboda, Jonathan G.; Meredith, Timothy C.; Lee, Kyungae; Campbell, Jennifer, Methods and compounds for antimicrobial intervention.
  149. Hatchwell, Eli; Eis, Peggy S.; Smith, III, Edward B.; Taoufik, Yassine, Methods for assessing risk of developing a viral disease using a genetic test.
  150. Hatchwell, Eli; Eis, Peggy S., Methods for detecting a genetic variation in subjects with parkinsonism.
  151. Reed Steven G., Methods for enhancement of protective immune responses.
  152. Reed, Steven G., Methods for enhancement of protective immune responses.
  153. Weiner, George; Hartmann, Gunther, Methods for enhancing antibody-induced cell lysis and treating cancer.
  154. Brown, Larry; McGeehan, John K.; Rashba-Step, Julia; Scott, Terrence L., Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation.
  155. Mathiowitz, Edith; Thanos, Christopher; Liu, Zhi, Methods for micronization of hydrophobic drugs.
  156. Wong, Chi-Huey; Wu, Chung-Yi, Methods for modifying human antibodies by glycan engineering.
  157. Sackler, Richard S.; Goldenheim, Paul D.; Chasin, Mark; Burch, Ronald M.; Reder, Robert F.; Tigner, Joseph, Methods for providing safe local anesthesia.
  158. Bamdad, Cynthia C., Methods for stimulating or enhancing proliferation of non-tumorous cells expressing MUC1 receptors.
  159. Childs, Richard William Wyatt; Takahashi, Yoshiyuki; Kajigaya, Sachiko; Harashima, Nanae, Methods of diagnosing renal cell carcinoma.
  160. Darvari, Ramin; Lambert, Adam; Rashba-Step, Julia E.; Yang, Mark X.; Zhang, Junhong; O'Connell, Ed, Methods of processing compositions containing microparticles.
  161. Piran, Uri; Mehr, Eugene; Brown, Larry R.; McGeehan, John K.; O'Connell, Ed, Methods of processing compositions containing microparticles.
  162. Piran, Uri, Methods of processing multi-phasic dispersions.
  163. Reed, Steven G., Methods of using a vaccine composition containing synthetic adjuvant.
  164. Reed, Steven G.; Carter, Darrick, Methods of using a vaccine composition containing synthetic adjuvant.
  165. Dow, Steven W.; Elmslie, Robyn E.; Schwarze, Jurgen Karl Johannes; Gelfand, Erwin W., Methods of using nucleic acid vector-lipid complexes.
  166. Mesens Jean,BEX ; Rickey Michael E. ; Atkins Thomas J., Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles 1,2-benzisothiazoles.
  167. Atkins, Thomas J.; Rickey, Michael E.; Mesens, Jean, Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles.
  168. Jean Mesens BE; Michael E. Rickey ; Thomas J. Atkins, Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles.
  169. Mesens Jean,BEX ; Rickey Michael E. ; Atkins Thomas J., Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles.
  170. Mesens Jean,BEX ; Rickey Michael E. ; Atkins Thomas J., Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles.
  171. Mesens, Jean; Rickey, Michael E.; Atkins, Thomas J., Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles.
  172. Mesens, Jean; Rickey, Michael E.; Atkins, Thomas J., Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles.
  173. Mesens,Jean; Rickey,Michael E.; Atkins,Thomas J., Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles.
  174. Jones, David Hugh; Farrar, Graham Henry; Clegg, James Christopher Stephen, Microencapsulated DNA for vaccination and gene therapy.
  175. Freyman, Toby M.; Levendusky, Joseph A., Microencapsulated compositions for endoluminal tissue engineering.
  176. Freyman, Toby M.; Levendusky, Joseph A., Microencapsulated compositions for endoluminal tissue engineering.
  177. Reid, Robert H.; VanHamont, John E.; Brown, William R.; Boedeker, Edgar C.; Thies, Curt, Microparticle carriers of maximal uptake capacity by both M cells and non-M cells.
  178. Hedley Mary Lynne ; Curley Joanne M. ; Langer Robert S., Microparticles for delivery of nucleic acid.
  179. Brown, Larry R.; Giannoukakis, Nick; Gillis, Kimberly A.; Trucco, Massimo, Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes.
  180. Brown, Larry R.; Giannoukakis, Nick; Trucco, Massimo, Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes.
  181. Nauss, Jeffrey; Reid, Robert; Wolf, Marcia Kay; Sadegh-Nasseri, Scheberazade, Model for testing immunogenicity of peptides.
  182. Glazer, Peter M.; Siedman, Michael M., Modified triple-helix forming oligonucleotides for targeted mutagenesis.
  183. Madasamy, Shanmugavel, Multi-subunit biological complexes for treatment of plaque-associated diseases.
  184. Baker, James R.; Rathinavelu, Sivaprakash; Makidon, Paul E.; LiPuma, John J.; Nigavekar, Shraddha, Nanoemulsion therapeutic compositions and methods of using the same.
  185. Baker, Jr., James R.; Rathinavelu, Sivaprakash; Makidon, Paul E.; LiPuma, John J.; Nigavekar, Shraddha, Nanoemulsion therapeutic compositions and methods of using the same.
  186. Henrich, Curtis J.; Kang, Moon-II; Bokesch, Heidi R.; Gustafson, Kirk R.; Colburn, Nancy H.; Young, Matthew R.; McMahon, James B., Nuclear factor kappa B pathway inhibitor composition and use of same.
  187. Brown, Larry R.; Gillis, Kimberly A.; Gallo, Michael V., Nucleic acid microparticles for pulmonary delivery.
  188. Brown, Larry R.; Scott, Terrence L.; Lafreniere, Debra; Bisker-Leib, Vered, Nucleic acid microspheres, production and delivery thereof.
  189. Scott, Terrence; Lafreniere, Debra; Bisker-Leib, Vered; Brown, Larry, Nucleic acid microspheres, production and delivery thereof.
  190. Pang Gerald Toh,AUX ; Clancy Robert Llewellyn,AUX ; Cripps Allan William,AUX ; Dunkley Margaret Lorraine,AUX, Oral vaccine comprising antigen surface-associated with red blood cells.
  191. Jarboe, Daniel L.; Reid, Robert H.; Boedeker, Edgar C.; Cassels, Frederick J., Oral-intestinal vaccines against diseases caused by enteropathic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.
  192. Zender, Lars; Lowe, Scott W.; Spector, Mona S., Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof.
  193. Basu,Sujit K.; Hrkach,Jeffrey; Lipp,Michael; Elbert,Katharina; Edwards,David A., Particles for inhalation having sustained release properties.
  194. Edwards, David A.; Hrkach, Jeffrey S., Particles for inhalation having sustained release properties.
  195. Edwards, David A.; Langer, Robert S.; Vanbever, Rita; Mintzes, Jeffrey; Wang, Jue; Chen, Donghao, Particles for inhalation having sustained release properties.
  196. Vanbever,Rita; Langer,Robert S.; Edwards,David A.; Mintzes,Jeffrey; Wang,Jue; Chen,Donghao, Particles for inhalation having sustained release properties.
  197. Batycky,Richard P.; Edwards,David A.; Lipp,Michael M., Particulate compositions for pulmonary delivery.
  198. Batycky,Richard P.; Edwards,David A.; Lipp,Michael M., Particulate compositions for pulmonary delivery.
  199. Hwang, Robin; Sullivan, Vincent; Huang, Juan; Wang, Zhaolin; Mikszta, John A.; Montgomery, David; Ford, Brandi; Bhuta-Wills, Anjana, Pharmaceutical compositions in particulate form.
  200. Mao, Hai-Quan; Lin, Kevin Y.; Hendriks, Bart S.; Leong, Kam W.; Haller, Michael F., Polymers for delivery of nucleic acids.
  201. Rosenthal, Arnon; Pons, Jaume; Ho, Wei-Hsien; Grimm, Jan Markus, Polynucleotides encoding antibodies directed against amyloid-beta peptide.
  202. Edwards, David A.; Langer, Robert S.; Vanbever, Rita; Mintzes, Jeffrey; Wang, Jue; Chen, Donghao, Preparation of novel particles for inhalation.
  203. Edwards David A. ; Langer Robert S. ; Vanbever Rita ; Mintzes Jeffrey ; Wang Jue ; Chen Donghao, Preparation of particles for inhalation.
  204. Mathiowitz Edith ; Chickering ; III Donald ; Jong Yong S. ; Jacob Jules S., Process for preparing microparticles through phase inversion phenomena.
  205. Mathiowitz, Edith; Chickering, III, Donald; Jong, Yong S.; Jacob, Jules S., Process for preparing microparticles through phase inversion phenomena.
  206. Brown,Larry R., Production of microspheres.
  207. Goldenheim Paul ; Lacouture Peter ; Donigi-Gale Donna ; Chasin Mark ; Sackler Richard, Prolonged anesthesia in joints and body spaces.
  208. Goldenheim, Paul; Donigi-Gale, Donna; Sackler, Richard; Lacouture, Peter; Chasin, Mark, Prolonged anesthesia in joints and body spaces.
  209. Brown, Larry; Bisker-Leib, Vered; LaFreniere, Debra; McGeehan, John; Rashba-Step, Julia; Scott, Terrence, Protein microspheres having injectable properties at high concentrations.
  210. Brown, Larry R.; Yang, Mark X.; O'Connell, Ed, Protein microspheres retaining pharmacokinetic and pharmacodynamic properties.
  211. Glazer, Peter M., Pseudocomplementary oligonucleotides for targeted gene therapy.
  212. Wong, Chi-Huey; Wu, Chung-Yi; Chuang, Hong-Yang; Ren, Chien-Tai, RM2 antigens and use thereof.
  213. Wong, Chi-Huey; Fang, Jim-Min; Shie, Jiun-Jie, Reactive labelling compounds and uses thereof.
  214. Plowman, Thomas Edward; Phillips, Erica M.; Hantke, Richard; Baird, Daniel; Rainone, Mike; Presley, Talbot, Recombinant bacteriophage for detection of nosocomial infection.
  215. Slack, Frank J.; Johnson, Steven M.; Grosshans, Helge, Regulation of oncogenes by microRNAs.
  216. Slack, Frank J.; Johnson, Steven M.; Grosshans, Helge; Weidhaas, Joanne Barnes, Regulation of oncogenes by microRNAs.
  217. Larsen, Janus Beierholm, Reimmunization and antibody design.
  218. Larsen, Janus Beierholm, Reimmunization and antibody design.
  219. Condon, Stephen M.; Deng, Yijun; Laporte, Matthew G.; Rippin, Susan R., SMAC Mimetic.
  220. Condon, Stephen M.; Deng, Yijun; LaPorte, Matthew G.; Rippin, Susan R., SMAC mimetic.
  221. Condon, Stephen M.; Deng, Yijun; LaPorte, Matthew G.; Rippin, Susan R., SMAC mimetic for treating myelodysplastic syndromes.
  222. Tam, Wai Leong; Weinberg, Robert A., Selective targeting of cancer stem cells.
  223. Rader, Christoph; Hofer, Thomas; Burke, Jr., Terrence; Thomas, Joshua, Selenocysteine mediated hybrid antibody molecules.
  224. Thompson, Peter Armstrong; Ledbetter, Jeffrey A.; Hayden-Ledbetter, Martha Susan; Grosmaire, Laura Sue; Bader, Robert; Brady, William, Single chain multivalent binding proteins with effector function.
  225. Edwards, David A.; Hrkach, Jeffrey S., Stable spray-dried protein formulations.
  226. Noelle Christine Vook ; Elliott Jacob ; Jean A. Setterstrom ; John van Hamont ; William Vaughan ; Ha Duong, Sustained release hydrophobic bioactive PLGA microspheres.
  227. Vook, Noelle Christine; Jacob, Elliott; Setterstrom, Jean A.; van Hamont, John; Vaughan, William; Duong, Ha, Sustained release hydrophobic bioactive PLGA microspheres.
  228. Vaughn, William M.; Van Hamont, John E.; Setterstrom, Jean A., Sustained release non-steroidal, anti-inflammatory and lidocaine PLGA microspheres.
  229. Reed, Steven G.; Carter, Darrick, Synthetic glucopyranosyl lipid adjuvants.
  230. Reed, Steven G.; Carter, Darrick, Synthetic glucopyranosyl lipid adjuvants.
  231. Reed, Steven G.; Carter, Darrick, Synthetic glucopyranosyl lipid adjuvants.
  232. Kelnar, Kevin; Brown, David, Synthetic mimics of miR-34.
  233. Kelnar, Kevin; Brown, David, Synthetic mimics of miR-34.
  234. Setterstrom, Jean A.; Tice, Thomas R.; Jacob, Elliot; Reid, Robert H.; van Hamont, John; Boedecker, Edgar C.; Jeyanthi, Ramassubbu; Friden, Phil; Roberts, F. Donald; McQueen, Charles E.; Bhattacharje, Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix.
  235. Setterstrom, Jean A.; Van Hamont, John E.; Reid, Robert H.; Jacob, Elliot; Jeyanthi, Ramasubbu; Boedeker, Edgar C.; McQueen, Charles E.; Jarboe, Daniel L.; Cassels, Frederick; Brown, William; Thies, , Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix.
  236. Reed, Steven G.; Carter, Darrick, Treatment of allergic conditions using a composition containing synthetic adjuvant.
  237. Terman David S. ; Stone Jay L., Tumor killing effects of enterotoxins, superantigens, and related compounds.
  238. Xu, Aimin; Wang, Yu; Lam, Karen Siu Ling, Use of lipocalin-2 as a diagnostic marker and therapeutic target.
  239. Reed, Steven G.; Carter, Darrick, Vaccine composition containing synthetic adjuvant.
  240. Reed, Steven G.; Carter, Darrick, Vaccine composition containing synthetic adjuvant.
  241. Reed, Steven G.; Carter, Darrick, Vaccine composition containing synthetic adjuvant.
  242. Reed, Steven G.; Carter, Darrick, Vaccine composition containing synthetic adjuvant.
  243. Bowersock, Terry L.; Guimond, Paul; Ju, Tzu-Chi R.; Kidane, Argaw, Vaccine composition, method of preparing the same, and method of vaccinating vertebrates.
  244. Burnett, Paul R.; van Hamont, John E.; Reid, Robert H.; Setterstrom, Jean A.; Van Cott, Thomas C.; Birx, Deborah L., Vaccines against intracellular pathogens using antigens encapsulated within biodegradable-biocompatible microspheres.
  245. Dubensky, Jr., Thomas W.; Hosken, Nancy A.; Robbins, Scott H.; Moore, Margaret D., Vaccines for HSV-2.
  246. Vaugn William M. ; Van Hamont John E. ; Setterstrom Jean A., sustained release non-steroidal, anti-inflammatory and lidocaine PLGA microspheres.
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