|국가/구분||United States(US) Patent 등록|
|미국특허분류(USC)||435/287 ; 435/1721 ; 435/313 ; 935/52|
|발명자 / 주소|
|출원인 / 주소|
|인용정보||피인용 횟수 : 60 인용 특허 : 0|
An apparatus is disclosed for the genetic transformation of organisms by accelerated particle mediated transformation. Foreign genes are introduced into cells by coating on carrier particles which are physically accelerated into the cells by positioning the carrier particles on a carrier sheet which is accelerated by a device which produces a shock wave. The treated cells are recovered, and a portion of them will contain in their genome the foreign gene. The procedure may be used to create genetically engineered organisms of many types.
An apparatus for the injection of carrier particles carrying genetic material into a target including living cells comprising: a thin planar carrier sheet; a plurality of small biologically inert carrier particles coated with genetic material disposed on the surface of the carrier sheet; a body forming a discharge chamber having an opening therein, the carrier sheet placed on the opening to seal the opening; means for generating a shock wave in the discharge chamber sufficient to accelerate the carrier sheet with the carrier particles thereon to travel t...