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Two step method for preparation of controlled release formulations 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C08J-009/28
출원번호 US-0644869 (1991-01-23)
발명자 / 주소
  • Won Richard (Palo Alto CA)
출원인 / 주소
  • Advanced Polymer Systems, Inc. (Redwood City CA 02)
인용정보 피인용 횟수 : 67  인용 특허 : 0

초록

Active substances intended for topical application are incorporated in novel formulations in which they are retained as impregnants inside the pores of porous solid particles or microspheres. The pores form a continuous network open to the exterior of the particles, permitting outward diffusion of t

대표청구항

A method for preparing a delivery system for an active substance, said method comprising: polymerizing monomers suspended in an immiscible phase in the presence of a porogen to form a plurality of rigid cross-linked polymer beads each defining a substantially non-collapsible internal pore network ha

이 특허를 인용한 특허 (67)

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  9. Lapidot, Noa; Magdassi, Shlomo; Avnir, David; Rottman, Claudio; Gans, Orit; Seri-Levy, Alon, Composition exhibiting enhanced formulation stability and delivery of topical active ingredients.
  10. Srinivas, Arutla; Bhagwatwar, Harshal P.; Arvind, Vakati Venkat; Perumal, Saravana; Narayana, Vemula Sathya; Rao, Mandavalli Srirama Sarveswara; Vobalaboina, Venkateswarlu; Sreedharala, Nookaraju Venkata, Compositions for drug delivery.
  11. Srinivas, Arutla; Bhagwatwar, Harshal P.; Arvind, Vakati Venkat; Perumal, Saravana; Narayana, Vemula Sathya; Rao, Mandavalli Srirama Sarveswara; Vobalaboina, Venkateswarlu; Sreedharala, Nookaraju Venkata, Compositions for drug delivery.
  12. Sertchook, Hanan; Toledano, Ofer; Bar-Simantov, Haim, Compositions for the treatment of rosacea.
  13. Toledano, Ofer; Sertchook, Hanan; Loboda, Natalia; Bar-Simantov, Haim; Shapiro, Leora; Abu-Reziq, Raed, Compositions for topical application comprising a peroxide and retinoid.
  14. Dihora, Jiten Odhavji; Hasegawa, Jun, Conditioner compositions with increased deposition of polyacrylate microcapsules.
  15. Dihora, Jlten Odhavji; Hasegawa, Jun, Conditioner compositions with increased deposition of polyacrylate microcapsules.
  16. Hayward James A. (4 Chuck Ct. Port Jefferson NY 11777) Goldstein Mindy S. (31 Southwick Ct. Plainview NY 11803) Brown Miriam (275 Candee Ave. Sayville NY 11782) Ceccoli Joseph D. (26 Neil Dr. Farming, Cosmetic delivery system for salicylic acid and process for preparation of same.
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  21. Dischler Louis ; Moyer Terry T. ; Henson Jimmy B., Dilatant powder coated fabric and containment articles formed therefrom.
  22. Yamamoto, Akira, Dosage form comprising an active ingredient and a plurality of solid porous microcarriers.
  23. Yamamoto, Akira, Dosage form comprising an active ingredient and a plurality of solid porous microcarriers.
  24. Yamamoto, Akira, Dosage form comprising an active ingredient and a plurality of solid porous microcarriers.
  25. Yamamoto, Akira, Dosage form comprising an active ingredient and a plurality of solid porous microcarriers.
  26. Steffier, Larry W.; Kurz, David; Raney, Robert R.; Robinson, Cary B., Durable film coating compositions having sustained slow-release capability, and methods of use therefor.
  27. Steffier, Larry; Kurz, David; Raney, Robert B.; Robinson, Cary B., Durable film coating compositions having sustained slow-release capability, and methods of use therefor.
  28. Morgan, Clyde E., Electrical producing creams.
  29. Singh, B. Sandhya; Saxena, Subhash J., Fluorouracil-containing formulation.
  30. Kitagawa Naotaka, Hydrophilic polymeric material.
  31. Kitagawa Naotaka, Hydrophilic polymeric material and method of preparation.
  32. Green, Howard; Compton, Bruce J.; Corey, George D.; Djian, Philippe, Linkage of agents to body tissue using microparticles and transglutaminase.
  33. Albright, Robert L.; Mapp, Richard, Low density polymer beads.
  34. Toledano, Ofer; Sertchook, Hanan; Loboda, Natalia; Bar-Simantov, Haim, Metal oxide coating of water insoluble ingredients.
  35. Davankov, Vadim; Tsyurupa, Maria; Pavlova, Ludmila, Method of making biocompatible polymeric adsorbing material for purification of physiological fluids of organism.
  36. Strzemiemski, Thomas M.; Micale, Fortunato J., Micro-encapsulated pepper-mustard composition and methods of using the same.
  37. Ugazio,Stephen Pierre Jean, Oil absorbing composition and process.
  38. Asotra, Satish; Gao, Shen; Yacobi, Avraham, Oral suspension of prednisolone acetate.
  39. Asotra, Satish; Gao, Shen; Yacobi, Avraham, Oral suspension of prednisolone acetate.
  40. Asotra, Satish; Gao, Shen; Yacobi, Avraham, Oral suspension of prednisolone acetate.
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  47. Luzenberg, Robert S., Porous plastic dispensing article.
  48. Sojka Milan F., Precipitation Polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and li.
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  50. Milan F. Sojka, Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof.
  51. Sojka Milan F., Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof.
  52. Sojka Milan F., Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the produ.
  53. Sojka Milan F., Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the product thereof.
  54. Sojka Milan F., Process for producing an oil sorbent copolymer and the product thereof.
  55. Sojka Milan F., Process for producing an oil sorbent copolymer and the product thereof.
  56. Wang, Yunzhang; Mabe, Thomas E., Puncture resistant composite.
  57. Froix Michael ; Pukshansky Masha ; Nacht Sergio, Retinoid formulations in porous microspheres for reduced irritation and enhanced stability.
  58. Vishnupad, Mohan; Vishnupad, Naomi, Retinoid solutions and formulations made therefrom.
  59. Dihora, Jiten Odhavji; Brown, Mark Anthony, Shampoo compositions with increased deposition of polyacrylate microcapsules.
  60. Dihora, Jiten Odhavji; Brown, Mark Anthony, Shampoo compositions with increased deposition of polyacrylate microcapsules.
  61. Calton Gary J. ; Siemer Sidney R. ; Wood Louis L., Slow release insect repellents.
  62. Tucci Raymond J. ; Dry Nathan M., Slow-release insect-repellent compositions and uses.
  63. Rinaldi Marie A. ; Saxena Subhash J. ; Tutschek Paul C., Softgel formulation containing retinol.
  64. Rinaldi Marie A. ; Saxena Subhash J. ; Tutschek Paul C., Softgel-compatible composition containing retinol.
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  66. Morgan, Clyde, Topical medicament.
  67. Ribeiro Dos Santos, Isabel; Sournac, Michel, Transdermal device including porous microparticles.
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