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특허 상세정보

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Process for preparing polynucleotides

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) C07H-015/12   
미국특허분류(USC) 536/27 ; 536/22 ; 536/23 ; 536/24
출원번호 US-0846453 (1986-03-31)
발명자 / 주소
출원인 / 주소
인용정보 피인용 횟수 : 160  인용 특허 : 0
초록

New and useful intermediate nucleotides bound to an inorganic polymer support, including the preparation thereof, and processes for the conversion to oligonucleotides which are especially useful for the synthesis of polynucleotides, particularly ribonucleic (RNA) and deoxyribonucleic (DNA) acids, are described.

대표
청구항

A process for the production of oligonnucleotides which comprises: (a) converting an inorganic silica into a coupling agent-silica, (b) combining the coupling agent-silica with a blocked nucleoside to obtain a blocked nucleoside-modified support; and (c) removing the blocking group from the blocked nucleoside-modified support to provide for the coupling of nucleotides to the nucleoside-modified support.

이 특허를 인용한 특허 피인용횟수: 160

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