|국가/구분||United States(US) Patent 등록|
|국제특허분류(IPC7판)||C12N-015/00 C12N-015/89 C12M-001/00|
|미국특허분류(USC)||435/1723 ; 435/1721 ; 435/287 ; 435/52|
|발명자 / 주소|
|출원인 / 주소|
|인용정보||피인용 횟수 : 194 인용 특허 : 0|
A process is described which uses a “cold”gas shock to accelerate microprojectiles wherein particles are presented to the gas shock on a planar surface perpendicular to the plane of expansion of the gas shock wave. Several different apparatus capable of accomplishing this method are described.
A method of introducing particles carrying biological materials into a target of cells, said method comprising the steps of: providing a planar carrier sheet having a target side, said sheet being a resilient membrane fixedly secured at its edges against movement, providing a target of cells, positioning particles carrying biological materials on the target side of the planar carrier sheet, and exposing said sheet to the force of an instantaneous cold gas shock wave so as to accelerate the particles free of the carrier sheet and to cause them to penetrat...