[특허]Rapid read-out sterility indicator

Rapid read-out sterility indicator 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	C12Q-001/22 C12M-001/12 C12M-001/34 C12M-001/40
출원번호	US-0277570 (1988-11-29)
발명자 / 주소	Foltz William E. (Cottage Grove MN) Matner Richard R. (St. Paul MN) Woodson Lewis P. (Eagan MN)
출원인 / 주소	Minnesota Mining and Manufacturing Company (St. Paul MN 02)
인용정보	피인용 횟수 : 53 인용 특허 : 0

초록 ▼

A unitary sterility indicator and a method for its use, the indicator comprising an outer container having liquid impermeable and gas non-absorptive walls, and having a gas-transmissive, bacteria impermeable opening therein; contained within the outer container, a detectable amount of a source of active enzyme and/or another microorganism commonly used to monitor sterilization; a sealed, openable gas and liquid impermeable inner container containing an aqueous medium and/or a nutrient growth medium, disposed in the outer container; an enzyme substrate system capable of reacting with active enzyme to produce a detectable enzyme-modified product and/or a detector material sensitive to microorganism growth, contained in one of the containers; and means contained within the outer container for restricting the area in which enzyme-modified product and/or growing microorganisms are contained, after the inner container is opened, to an area which is less than the volume of aqueous solution contained in the inner container.

대표청구항 ▼

A unitary sterility indicator comprising: a) an outer container having liquid impermeable and substantially gas non-absorptive walls, said container having at least one opening therein; b) gas-transmissive, bacteria-impermeable means covering said at least one opening; c) contained within said outer container a source of active enzyme which provides a detectable amount of said enzyme, said enzyme having sufficient activity following a sterilization cycle which is sublethal to at least one test microorganism commonly used to monitor sterilization, to react with an effective amount of a substrate system for said enzyme to produce a detectable enzyme-modified product within less than twenty-four hours, yet said enzyme having activity which is reduced to “background”following a sterilization cycle which is lethal to said test microorganism; d) a sealed, openable gas and liquid impermeable inner container, containing an aqueous reaction medium capable of permitting said active enzyme to react with a substrate system for said enzyme, said inner container being disposed in said outer container and said inner container, when opened, permitting said aqueous reaction medium to contact said source of active enzyme; e) an enzyme substrate system contained in at least one of said containers and capable of reacting in the presence of said aqueous reaction medium with an active enzyme surviving said sublethal sterilization cycle to produce a detectable enzyme-modified product; and f) means contained within said outer container for restricting the volume in which the enzyme-modified product is contained, after said inner container is opened and said medium is allowed to contact said source of active enzyme, to a volume which is less than the volume of said aqueous reaction medium contained in said inner container.

이 특허를 인용한 특허 (53)

Bolea Phillip A. ; Rosenlund Thomas T., Apparatus for reading a plurality of biological indicators.
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Dalmasso Joseph P. ; Freeman David A., Biological indicator for detection of early metabolic activity.
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Ahimou, Francois; Bennaars-Eiden, Assumpta; Foltz, William E.; Swaminathan, Swarnalatha, Biological indicator for monitoring a low-temperature sterilization process.
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Felkner,Ira C.; Laico,Joseph P., Biological indicator system to detect effectiveness of sterilization.
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Woodson Lewis P., Biological sterilization indication for use with or without test pack materials or devices.
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Chandrapati, Sailaja; Webb, Heather M.; Pederson, Jeffrey C.; Smith, Jeffrey D.; Duda, RuthAnn R.; Engel, Brian J., Biological sterilization indicator.
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Chandrapati, Sailaja; Webb, Heather M.; Pederson, Jeffrey C.; Smith, Jeffrey D.; Duda, RuthAnn R.; Engel, Brian J., Biological sterilization indicator.
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Witcher, Kelvin J.; Foltz, William E.; Jing, Naiyong, Biological sterilization indicator.
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Smith, Jeffrey D.; Pederson, Jeffrey C.; Chandrapati, Sailaja, Biological sterilization indicator and method of using same.
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Smith, Jeffrey D.; Pederson, Jeffrey C.; Chandrapati, Sailaja, Biological sterilization indicator and method of using same.
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Smith, Jeffrey D.; Pederson, Jeffrey C.; Chandrapati, Sailaja; Duda, RuthAnn R., Biological sterilization indicator and method of using same.
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Smith, Jeffrey D.; Pederson, Jeffrey C.; Chandrapati, Sailaja; Duda, RuthAnn R., Biological sterilization indicator and method of using same.
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Pederson, Jeffrey C.; Chandrapati, Sailaja; Behun, Bryan S.; Robole, Barry W.; Longworth, Leroy J., Biological sterilization indicator method.
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Pederson, Jeffrey C.; Chandrapati, Sailaja; Behun, Bryan S.; Robole, Barry W.; Longworth, Leroy J., Biological sterilization indicator system and method.
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Pederson, Jeffrey C.; Chandrapati, Sailaja; Behun, Bryan S.; Robole, Barry W.; Longworth, Leroy J.; Chen, Kaileen, Biological sterilization indicator system and method.
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Chandrapati, Sailaja; Pederson, Jeffrey C.; Webb, Heather M.; Smith, Jeffrey D.; Halverson, Kurt J.; Behun, Bryan S.; Ludowise, Peter D., Biological sterilization indicator, system, and methods of using same.
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Chandrapati, Sailaja; Pederson, Jeffrey C.; Webb, Heather M.; Smith, Jeffrey D.; Halverson, Kurt J.; Behun, Bryan S.; Ludowise, Peter D., Biological sterilization indicator, system, and methods of using same.
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Durand M. Smith ; Dale S. Winger ; Joshua N. Brown, Cold water disinfection of foods.
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Cooper Theodore R. ; Toney Allyson T. ; McParlane John B., Cold water ozone disinfection.
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Cooper Theodore R. ; Toney Allyson T. ; McParlane John B., Cold water ozone disinfection.
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Cooper Theodore R. ; Toney Allyson T. ; McParlane John B., Cold water wash formula.
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Klein, Frank Eric; Wheeler, Andrew John; DenHartigh, Andrew John; Hoerner, William; Borich, Damon; Obregon, Zwckxally; Grbavac, Andrea; Borich, Karen; Silveyra, Alejandro, Fluid retainer cartridge assembly and method for utilizing the same.
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Franciskovich, Phillip P.; Yirava, William A.; Cregger, Tricia A., Genetically engineered biological indicator.
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Franciskovich, Phillip P.; Yirava, William A.; Cregger, Tricia A., Genetically engineered biological indicator.
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Franciskovich, Phillip P.; Yirava, William A.; Cregger, Tricia A., Genetically engineered biological indicator.
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Hendricks Judy K. ; Rechsteiner Shaundrea L ; Gorski Joel R., Indicator systems for determination of sterilization.
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Hendricks Judy K. ; Rechsteiner Shaundrea L. ; Gorski Joel R., Indicator systems for determination of sterilization.
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Salter, Robert S.; Saul, Steven J.; Rossi, Martin T., Inhibition assay method and device for detection of antibiotics.
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Yves Levi FR; Daniele Touati FR; Sam Dukan FR, Method for adjusting and disinfecting liquids.
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Chandrapati, Sailaja; Webb, Heather M.; Pederson, Jeffrey C.; Halverson, Kurt J.; Engel, Brian J., Method of detecting a biological activity.
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Chandrapati, Sailaja; Webb, Heather M.; Pederson, Jeffrey C.; Halverson, Kurt J.; Engel, Brian R., Method of determining efficacy of a sterilization process.
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Felkner, Ira C.; Laico, Joseph P., Methods, compositions and kits for biological indicator of sterilization.
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Patel, Gordhanbhai N, Monitoring system based on etching of metals.
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Witcher, Kelvin J.; Foltz, William E.; Jing, Naiyong, Nanostructured spore carrier.
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Franciskovich, Phillip P.; Cregger, Tricia A.; Duda, Mark J., Process for determining the effectiveness of a sterilization.
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Albert Heidemarie,ZAX ; Foltz William F. ; Woodson Lewis P., Protective housing for biological indicator for testing the effectiveness of a sterilization procedure.
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Matner Richard R. (St. Paul MN) Foltz William E. (Cottage Grove MN) Woodson Lewis P. (Eagan MN), Rapid read-out biological indicator.
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Matner, Richard R.; Foltz, William E.; Woodson, Lewis P., Rapid read-out biological indicator.
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Skiffington, Richard T.; Salter, Robert S.; Fitchen, John F., Sampling method and device.
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Pasmore, Mark Edward; Franciskovich, Phillip P.; Cregger, Tricia A.; Solomon, Alan M., Self-contained biological indicator.
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Pasmore, Mark Edward; Solomon, Alan M., Self-contained biological indicator.
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Smith Daniel F. (Irvine CA), Self-contained biological indicator.
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Falkowski Jerry ; Shamsunder Giridhar ; Risner Steven J. ; Lyons Pamela M., Self-contained biological indicator for non traditional sterilization methods.
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Smith, Jeffrey D.; Pederson, Jeffrey C.; Chandrapati, Sailaja, Sterility indicator vial.
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Franciskovich, Phillip P.; Cregger, Tricia A.; Duda, Mark J., Sterilization indicator.
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Franciskovich, Phillip P.; Cregger, Tricia A.; Duda, Mark J., Sterilization indicator.
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Witcher,Kelvin J.; Foltz,William E.; Chandrapati,Sailaja; Rosenlund,Thomas T.; Asmus,Robert A.; Lulich,Ronald G., Sterilization indicator test packs.
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Foltz, William E.; Asmus, Robert A.; Lulich, Ronald G., Sterilization indicator with chemically stabilized enzyme.
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William E. Foltz ; Robert A. Asmus ; Ronald G. Lulich, Sterilization indicator with chemically stabilized enzyme.
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Bolea Phillip A., System for measuring the efficacy of a sterilization cycle.
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John R. Gillis, Testing for bacterial sterilizing effectiveness, and test indicator manufacture and use.
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Haarer, Dietrich; Levy, Yoav, Time-temperature indicating device.
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Narayan K. Ananth (Framingham MA), Time-temperature method for establishing lethality of high temperature food processing.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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연합인증

Rapid read-out sterility indicator 원문보기

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Rapid read-out sterility indicator 원문보기

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연구과제 타임라인

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이 특허를 인용한 특허 (53)

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