|국가/구분||United States(US) Patent 등록|
|미국특허분류(USC)||604/35 ; 604/82 ; 604/902 ; 606/94|
|발명자 / 주소|
|인용정보||피인용 횟수 : 183 인용 특허 : 0|
A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be applied generally to provide such compositions. Also disclosed are an apparatus and method for application of sealant comprising this fibrinogen adhesive composition.
An applicator device for dispensing a two-component system into an animal subject, which applicator comprises a first and second dispensing means each having an inlet end and an outlet end disposed in parallel so as to permit the two components to be mixed when dispensing pressure is applied to the first and the second dispensing means; a means for applying equal dispensing pressure to said first and second dispensing means; and disposed adjacent to said first and second outlet ends, a means to apply suction adjacent to and at said outlet ends, and means...