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Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/12
  • A61K-009/127
출원번호 US-0834111 (1992-02-11)
발명자 / 주소
  • Evans Richard M. (Westwood MA) Farr Stephen J. (Llandaf GB7)
출원인 / 주소
  • University of Wales College of Cardiff (GBX 03)
인용정보 피인용 횟수 : 140  인용 특허 : 0

초록

Highly purified and recombinantly produced polypeptides and proteins can be provided to a patient to treat systemic disorders using a metered dose inhaler (MDI). The polypeptides and proteins are solubilized in reverse micelles formed from the surfactant in the MDI propellant. By controlling the mol

대표청구항

An aerosol formulation for delivery of insulin to a patient\s lungs, comprising: at least ninety percent by weight of a propellant; less than ten percent by weight of insulin; up to 5% weight in volume of a surfactant; and an amount of water associated with said surfactant which results in a molar r

이 특허를 인용한 특허 (140)

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