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특허 상세정보

Ascorbate interference-resistant composition, device and method of assaying for predetermined analyte

국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) C12Q-001/28    G01N-033/20   
미국특허분류(USC) 435/28 ; 435/4 ; 435/10 ; 435/11
출원번호 US-0699317 (1991-05-13)
발명자 / 주소
출원인 / 주소
인용정보 피인용 횟수 : 18  인용 특허 : 0
초록

A new and improved test device and method of determining the presence or concentration of a predetermined analyte, such as glucose, cholesterol or occult blood, in a test sample are disclosed. The test device includes a test pad comprising a suitable carrier matrix incorporating an indicator reagent composition capable of interacting with the predetermined analyte to produce a detectable or measurable response. In addition, the new and improved indicator reagent composition, comprising an indicator dye, such as a redox indicator, like a benzidine indicat...

대표
청구항

A composition which exhibits a sufficient color transition upon contacting a test sample to demonstrate the presence or concentration of a predetermined analyte in the test sample, wherein the predetermined analyte interacts with an oxidase enzyme or exhibits peroxidase activity, comprising: (a) an indicator dye; (b) a redox mediator; (c) a metal ion complex which includes a metal ion selected from the group consisting of ferric ion, mercuric ion, stannic ion, nickel(II) ion, magnesium(III) ion, cadmium(II) ion, zinc(II) ion, molybdenum(V) ion, chromium(...

이 특허를 인용한 특허 피인용횟수: 18

  1. Chang, Kevin. Analyte-testing device. USP2016049305138.
  2. Chang, Kevin. Analyte-testing device. USP2015028945930.
  3. Chang, Kevin. Analyte-testing device. USP2015079092557.
  4. Chang, Kevin. Analyte-testing device. USP2012118309357.
  5. Chang, Kevin. Analyte-testing device. USP2014038679847.
  6. Pugia Michael (Granger IN). Ascorbate resistant detection of hydrogen peroxide. USP1997125702955.
  7. Pugia Michael J.. Competitive apo-peroxidase assay. USP2001056228602.
  8. Paul,Buddha D.. Detection of oxidizing agents in urine. USP2008117445908.
  9. Marfurt, Karen L.; Warchal-Windham, Mary Ellen. Determining the concentration of analytes in sample by direct mediation of enzymes. USP2011017867728.
  10. Rheinheimer, Gary W.; Yip, Meitak Teresa. Formulation for reducing urea effect for immunochromatography assays using urine samples. USP2004116824985.
  11. West Steven J. (Hull MA) Tsagatakis John K. (Iraklion GRX) Wen Xiaowen (Lexington MA). Interference suppressing buffer. USP1997075651876.
  12. Charles R. Carpenter ; Melanie Tornberg ; Genevieve Clark. Methods for the detection and identification of crystals in biological fluids. USP2002076413778.
  13. Cregger, Tricia; Eveland, Randal W.; Bower, Antoinette. Oxidative dye composition and indicator. USP2013078481331.
  14. Ogura,Yoshikazu; Yamasaki,Seiji; Naitoh,Koichi. Packaged beverages. USP2007057220444.
  15. Ogura, Yoshikazu; Yamasaki, Seiji; Naitoh, Koichi. Packaged beverages containing β-cyclodextrin. USP2011017862847.
  16. Jeon, Sung-Il; Jung, Sung-Kwon; Im, Seung-Min; Lee, Eun-Sang; Kim, Se-Ho; Suk, Hong-Seong; Kim, Won-Dong; Koh, Jae-Min. Reagent composition for biosensor and biosensor having the same. USP2016119493808.
  17. Jeon, Sung-Il; Jung, Sung-Kwon; Im, Seung-Min; Lee, Eun-Sang; Kim, Se-Ho; Suk, Hong-Seong; Kim, Won-Dong; Koh, Jae-Min. Reagent composition for biosensor and biosensor having the same. USP2018049938556.
  18. Marfurt, Karen L.. Size self-limiting compositions and test devices for measuring analytes in biological fluids. USP2018059982289.