[특허]Ablatable mask of polyoxyalkylene polymer and ionic polysaccharide gel for laser reprofiling of the cornea

Ablatable mask of polyoxyalkylene polymer and ionic polysaccharide gel for laser reprofiling of the cornea 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-009/04 A61B-006/10 A61K-009/10 A61K-047/44 A61K-047/36 A61K-047/38
출원번호	US-0604705 (1990-10-26)
발명자 / 주소	Viegas Tacey X. (Ann Arbor MI) Reeve Lorraine E. (Ann Arbor MI) Henry Raymond L. (Grosse Pointe Woods MI)
출원인 / 주소	Mediventures, Inc. (Grosse Pointe Park MI 02)
인용정보	피인용 횟수 : 50 인용 특허 : 0

초록 ▼

Balanced pH, thermo-irreversible polyoxyalkylene polymer and ionic polysaccharide gels are ideal materials for use as an ablatable mask or coating over the cornea of the eye of a mammal during excimer laser keratectomy. The depth and smoothness of the ablated corneal surface can be controlled by molding the desired surface curvature into the mask surface using a contact lens as a mold which is pressed onto the gel surface coating the cornea.

대표청구항 ▼

An ablatable corneal mask for use in excimer laser keratectomy for correction of myopia and hyperopia, said mask comprising a thermally irreversible, osmotically balanced aqueous gel, having a buffered pH, wherein said aqueous gel is the reaction product of a thermally reversible aqueous gel and a multivalent counter-ion, wherein said thermally reversible aqueous gel is a liquid at room temperature or below and a gel at mammalian body temperature, said thermally reversible aqueous gel containing (1) about 0.2% to about 2.5% by weight of an ionic polysaccharide; (2) about 10% to about 50% by weight of a polyoxyalkylene block copolymer of formula Y[(A)n－E－H]x (I) wherein A is a polyoxyalkylene moiety having an oxygen/carbon atom ratio of less than 0.5, x is at least 2, Y is derived from water or an organic compound containing x reactive hydrogen atoms, E is a polyoxyethylene moiety constituting at least 60% by weight of the polyoxyalkylene block copolymer, n has a value such that the average molecular weight of A is at least about 500, as determined by the hydroxyl number of an intermediate of formula Y[(A)n－H]x (II) and the total average molecular weight of the polyoxyalkylene block copolymer is at least about 5000; and (3) a pharmaceutically acceptable buffer sufficient to maintain the pH of said thermally reversible aqueous gel at a desired level; wherein the muiltivalent counter-ion is capable of thermo-irreversibly gelling the ionic polysaccharide in the thermally reversible aqueous gel.

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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
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저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
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연합인증

Ablatable mask of polyoxyalkylene polymer and ionic polysaccharide gel for laser reprofiling of the cornea 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허를 인용한 특허 (50)

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연합인증

Ablatable mask of polyoxyalkylene polymer and ionic polysaccharide gel for laser reprofiling of the cornea 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

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이 특허를 인용한 특허 (50)

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