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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0937464 (1992-08-28) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 601 인용 특허 : 0 |
A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall
A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.
A drug delivery apparatus having a distal end and a proximal end for local delivery of a drug to internal body tissue comprising: (a) a flexible catheter for insertion into an internal target area of a body; (b) drug delivery means connected to said catheter for delivering a drug to said target area
A drug delivery apparatus having a distal end and a proximal end for local delivery of a drug to internal body tissue comprising: (a) a flexible catheter for insertion into an internal target area of a body; (b) drug delivery means connected to said catheter for delivering a drug to said target area, said drug delivery means having a fluid delivery passageway for delivering said drug to said distal end, an outer wall and a selectively permeable microporous outer membrane portion proximate said distal end of said drug delivery apparatus, said microporous outer membrane further comprising pores sized from about 10 Åto about 1 micron and at least one impermeable end portion to enhance precise delivery of said drug to said internal target area; and (c) phoresis means for assisting the transport of said drug across said selectively permeable microporous outer membrane.
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