초록 ▼

An aqueous vaginal douche which is at most marginally effective against bacteria but which includes a fungicidal/fungistatic agent to rid the vaginal zone of yeasts. The douche may include a penetrating agent and/or an adherent to hold the fungicidal/fungistatic agent to the vaginal tissues. The dou

An aqueous vaginal douche which is at most marginally effective against bacteria but which includes a fungicidal/fungistatic agent to rid the vaginal zone of yeasts. The douche may include a penetrating agent and/or an adherent to hold the fungicidal/fungistatic agent to the vaginal tissues. The douche is inserted into the vagina by means of a nozzle or the like. The douche may incorporate a carrier or solvent for the fungicidal/fungistatic agent and may further include a preservative.

대표청구항 ▼

An aqueous antifungal vaginal douche composition consisting essentially of an antifungal agent selected from the group consisting fomiconazole, clotrimazole, ketoconazole and nystatiin in an amount effective to kill and/or inhibit the growth of yeasts or fungi in the vagina, a penetrating agent sele

An aqueous antifungal vaginal douche composition consisting essentially of an antifungal agent selected from the group consisting fomiconazole, clotrimazole, ketoconazole and nystatiin in an amount effective to kill and/or inhibit the growth of yeasts or fungi in the vagina, a penetrating agent selected from the group consisting of ethoxylated alcohols, ethoxylated alkylphenols, ethoxylated fatty acids, ethoxylated castor oil, alkanolamides, ethylene glycol/propylene glycol copolymers, ethoxylated sorbitol, ethoxylated sorbitol esters, ethoxylated glycerol esters, alkyl sulfosuccinates, alkyl sulfonates, alkyl sulfates, alkyl aryl sulfonates, alkyl aryl sulfates, phosphate esters and betaines in an amount effective to enhance penetration of the antifungal agent into vaginal tissue, an adherent agent selected from the group consisting of arabic, align, guar, tragacanth and xanthan gums, pectin, dextran, sodium carboxymethyl cellulose, methyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxyethyl methyl cellulose, polyvinyl alcohol, polyacrylic acid and acidic gums in an amount effective to enhance adherence of the antifungal agent to vaginal tissue and a carrier or solvent selected from the group consisting of polyethylene glycols, polyoxyethylene glycols, polypropylene glycols and polyoxypropylene glycols, wherein said douche composition has a pH of about 5.5. to 8.5 and will not disturb the normal bacterial balance in the vagina.