초록 ▼

An apparatus for simultaneously delivering more than one kind of medicament to an eye, without premixing of the medicaments within the apparatus. The apparatus includes a special nozzle assembly which precludes reentry of medicament expelled from the nozzle to prevent commingling of the medicaments.

An apparatus for simultaneously delivering more than one kind of medicament to an eye, without premixing of the medicaments within the apparatus. The apparatus includes a special nozzle assembly which precludes reentry of medicament expelled from the nozzle to prevent commingling of the medicaments. In this way, dosages of two or more medicaments may be simultaneously delivered to an eye without the need for creating a stable premixture of the medicaments.

대표청구항 ▼

1. An apparatus for applying medicaments to an eye, comprising: a vial; a means for partitioning said vial into a first medicament chamber and a second medicament chamber which precludes commingling of medicament in the first chamber with medicament in the second chamber; and a nozzle coupled i

1. An apparatus for applying medicaments to an eye, comprising: a vial; a means for partitioning said vial into a first medicament chamber and a second medicament chamber which precludes commingling of medicament in the first chamber with medicament in the second chamber; and a nozzle coupled in fluid communication with the first and second medicament chambers, the nozzle defining a tight interface therein normally in a closed position which prevents passage of medicament through the nozzle and which opens in response to a flow of medicament of sufficient pressure to permit passage of said flow of medicament through the nozzle for release into the eye. 2. An apparatus as defined in claim 1, wherein the nozzle includes an outer nozzle forming member and an inner nozzle forming member received within the outer nozzle forming member and the interface is defined therebetween. 3. An apparatus as defined in claim 1, further comprising a first piston means for pressurizing medicament in the first chamber to flow through the interface for release into the eye and a second piston means for pressurizing medicament in the second chamber to flow through the interface for release into the eye. 4. An apparatus as defined in claim 3, wherein the first piston means is seated within a first piston cavity coupled in fluid communication with the interface and the first medicament chamber, and the second piston means is seated within a second piston cavity coupled in fluid communication with the interface and the second medicament chamber, and wherein the first and second piston means are moveable within the respective piston cavities to cause medicament within each piston cavity to flow through the interface for release into the eye. 5. An apparatus as defined in claim 4, wherein each piston cavity is dimensioned to release a predetermined volume of medicament into the eye. 6. An apparatus as defined in claim 4, wherein each piston cavity is coupled in fluid communication with the respective medicament chamber by at least one aperture, and each piston means causes the medicament within the respective piston cavities to flow through the interface upon passing the at least one aperture when driven to pressurize medicament. 7. An apparatus as defined in claim 3, wherein each piston means includes a piston head fixed in a flexible wall of the vial for facilitating driving of the piston means. 8. An apparatus as defined in claim 2, wherein the outer nozzle forming member is made of a more flexible material in comparison to the inner nozzle forming member for facilitating opening of the interface in response to a flow of medicament of sufficient pressure for release through the nozzle into the eye. 9. An apparatus as defined in claim 3, wherein the outer nozzle forming member is made of a more flexible material in comparison to the inner nozzle forming member for facilitating opening of the interface in response to a flow of medicament of sufficient pressure for release through the nozzle into the eye. 10. An apparatus as defined in claim 7, wherein the outer nozzle forming member is an integral part of the flexible wall of the vial. 11. An apparatus as defined in claim 10, wherein the portion of the vial wall which comprises the outer nozzle forming member has a thickness which is thinner than the remainder of the vial wall for facilitating opening of the interface. 12. An apparatus as defined in claim 6, wherein each piston means includes a rim which makes contact with an inner surface of the respective piston cavity for facilitating pushing of medicament in the piston cavity into the interface during driving of the piston means. 13. An apparatus as defined in claim 1, further comprising a first medicament held in the first chamber and a second medicament, different from the first medicament, held in the second chamber. 14. An apparatus for simultaneously delivering a plurality of different medicaments to an eye without commingling of the different medicaments within the apparatus comprising: a vial having an outer body which defines an outer nozzle forming section at an anterior end of the apparatus; a means for partitioning the vial into a first medicament chamber and a second medicament chamber, said means for partitioning preventing commingling of medicament in the first chamber with medicament in the second chamber; an inner nozzle forming body which is received within the outer nozzle forming section of the outer body, an outer surface of the inner nozzle forming body making surface to surface contact with an inner surface of the outer nozzle forming section of the outer body to define a normally closed interface terminating at an anterior nozzle tip, the closed interface preventing passage of medicament through the nozzle; means defining a first drop cavity in fluid communication with the first medicament chamber; means defining a second drop cavity in fluid communication with the second medicament chamber; means for preventing commingling of medicament in the first drop cavity with medicament in the second drop cavity; means for forcing a dosage of a first medicament in the first drop cavity to flow into and open the interface and to flow out of the apparatus through the nozzle; and means for forcing a dosage of a second medicament in the second drop cavity to flow into and open the interface and to flow out of the apparatus through the nozzle, whereby the interface immediately closes upon expulsion of said dosages of said first and second medicaments out of the nozzle thereby preventing reentry of medicament into the apparatus. 15. The apparatus according to claim 14, wherein the outer nozzle forming section is flexible relative to the inner nozzle forming body for facilitating opening of the interface and the nozzle in response to forced flow of dosages of medicament from the drop cavities. 16. The apparatus according to claim 14, wherein each means for forcing is a piston which is seated within the respective drop cavity and which is slideable in the respective drop cavity to push medicament from the drop cavity into the interface. 17. The apparatus according to claim 16, wherein the outer body of the vial is flexible and wherein each piston includes a piston head which is disposed within the outer body of the vial for facilitating driving of the pistons. 18. The apparatus according to claim 14, further comprising means defining a first channel between the first drop cavity and the interface and means defining a second channel between the second drop cavity and the interface, the first channel being isolated from the second channel. 19. The apparatus according to claim 14, wherein each drop cavity is dimensioned to release a predetermined volume of medicament into the eye.