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Panels of analyte-binding ligands 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B01D-015/08
출원번호 US-0049642 (1993-04-09)
발명자 / 주소
  • Kauvar Lawrence M. (San Francisco CA)
출원인 / 주소
  • Terrapin Technologies, Inc. (San Francisco CA 02)
인용정보 피인용 횟수 : 49  인용 특허 : 0

초록

The invention provides methods to obtain panels of low molecular weight polymers resulting from varying constituent monomers, which panels are systematically diverse with respect to two or more variables. The panels can be screened for members (paralogs) which are capable of specifically binding a t

대표청구항

A chromatographic support gradient containing paralogs which comprises a solid support having distributed thereon in a predetermined pattern at least a portion of the individual paralogs of a panel of individual paralogs wherein said individual paralogs have systematically varied values of at least

이 특허를 인용한 특허 (49)

  1. Lally Michael T. ; Leavesley Peter J. ; Lockman Robert D. ; Van Davelaar Peter C., Apparatus and method for sealing a plurality of chromatography columns.
  2. Zuckermann, Ronald N.; Beausoleil, Eric; Wachowicz, Matthew; Kothakota, Srinivas, Biological sample component purification and differential display.
  3. Chait, Arnon; Zaslavsky, Boris, Characterization of molecules.
  4. Chait, Arnon; Zaslavsky, Boris Y., Characterization of molecules.
  5. Carlson, Robert E., Combinatorial artificial receptors including peptide building blocks.
  6. Carlson,Robert E., Combinatorial artificial receptors including tether building blocks.
  7. Carlson, Robert E., Combinatorial artificial receptors including tether building blocks on scaffolds.
  8. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  9. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  10. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  11. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Compositions and methods for identifying and targeting cancer cells of alimentary canal origin.
  12. Waldman Scott A. ; Pearlman Joshua M. ; Barber Michael T. ; Schulz Stephanie ; Parkinson Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  13. Waldman,Scott A.; Pearlman,Joshua M.; Barber,Michael T.; Schulz,Stephanie; Parkinson,Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  14. Waldman,Scott A.; Pearlman,Joshua M.; Barber,Michael T.; Schulz,Stephanie; Parkinson,Scott J., Compositions that specifically bind to colorectal cancer cells and methods of using the same.
  15. Jindal, Satish; Regnier, Fred; Williams, Kevin; Afeyan, Noubar; Paliwal, Sandeep; Evans, David; Pingali, Aruna, High speed, automated, continuous flow, multi-dimensional molecular selection and analysis.
  16. Pantoliano,Michael W; Salemme,Francis R; Carver, Jr.,Theodore E, High throughput method for functionally classifying proteins identified using a genomics approach.
  17. Irving Wainer ; Yanxiao Zhang, Immobilization of membrane receptor on HPLC.
  18. Wainer Irving ; Zhang Yanxiao, Immobilization of membrane receptor on HPLC.
  19. Zambias, Robert; Bolten, David A.; Hogan, Joseph C.; Furth, Paul; Casebier, David; Tu, Cheng, Logically ordered arrays of compounds and methods of making and using the same.
  20. al., Method and apparatus for transferring and combining distinct chemical compositions with reagents.
  21. Chait, Arnon; Zaslavsky, Boris Y., Method for measuring solubility.
  22. Geysen Hendrik Mario,AUX, Method for the use and synthesis of peptides.
  23. Chait, Arnon; Zaslavsky, Boris Y., Methods and devices for determining a disease state.
  24. Weinberg David ; Waldman Scott A. ; Barber Michael T. ; Biswas Sanjoy, Methods of identifying and detecting pancreatic cancer.
  25. Carlson,Robert E, Methods of making arrays and artificial receptors.
  26. Waldman, Scott A.; Park, Jason; Schulz, Stephanie, Methods of screening and diagnosing esophageal cancer by determining guanylin cyclase C expression.
  27. Waldman Scott A., Methods of treating metastatic colorectal cancer with ST receptor binding compounds.
  28. Waldman, Scott A.; Pearlman, Joshua M.; Barber, Michael T.; Schulz, Stephanie; Parkinson, Scott J.; Prawer, Scott, Methods of using CRCA-1 as a stomach and esophageal cancer marker.
  29. Charych,Deborah; Beausoleil,Eric; Zuckermann,Ronald N., Microarrays on mirrored substrates for performing proteomic analyses.
  30. Schultz, Peter G.; Wang, Lei, Protein arrays.
  31. Charych,Deborah; Zuckermann,Ronald N., Protein microarrays on mirrored surfaces for performing proteomic analyses.
  32. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology.
  33. Hutchens, T. William; Yip, Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  34. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  35. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  36. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  37. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  38. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  39. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  40. Hutchens,T. William; Yip,Tai Tung, Retentate chromatography and protein chip arrays with applications in biology and medicine.
  41. Hutchens, T. William; Yip, Tai-Tung, Retentate chromatography—profiling with biospecific interaction adsorbents.
  42. Waldman, Scott A., ST receptor binding compounds and methods of using the same.
  43. Carlson,Robert E., Sensors employing combinatorial artificial receptors.
  44. Chait, Arnon; Zaslavsky, Boris Y., Systems and methods for characterization of molecules.
  45. Chait, Arnon; Zaslavsky, Boris Y., Systems and methods for characterization of molecules.
  46. Chait, Arnon; Zaslavsky, Boris Y., Systems and methods involving data patterns such as spectral biomarkers.
  47. Chait, Arnon; Zaslavsky, Boris Y., Systems and methods involving data patterns such as spectral biomarkers.
  48. Waldman, Scott A.; Pitari, Giovanni Mario; Park, Jason; Schulz, Stephanie; Wolfe, Henry R.; Lubbe, Wilhelm, Use of GCC ligands.
  49. Hutchens T. William ; Yip Tai-Tung, Use of retentate chromatography to generate difference maps.
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