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Lyophilized ligand-receptor complexes for assays and sensors 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/543
  • G01N-033/566
  • G01N-033/569
출원번호 US-0092518 (1993-07-16)
발명자 / 주소
  • Ligler Frances S. (Potomac MD) Whelan James P. (Potomac MD)
출원인 / 주소
  • The United States of America as Represented by the Secretary of the Navy (Washington DC 06) U.S. Drug Testing, Inc. (Rancho Cucamonga CA 02)
인용정보 피인용 횟수 : 36  인용 특허 : 0

초록

A dry reagent prepared by lyophilizing a labelled ligand-immobilized receptor complex or a labelled receptor-immobilized ligand complex is, on rehydration, useful for detecting analytes in samples in a variety of displacement assays.

대표청구항

A lyophilized ligand-receptor complex, prepared by a process comprising: (i) binding a labelled ligand or a labelled receptor to an immobilized receptor or an immobilized ligand, to obtain an immobilized ligand-receptor complex; (ii) washing said immobilized ligand-receptor complex to remove any exc

이 특허를 인용한 특허 (36)

  1. Hood, Leroy E.; Jung, Edward K.Y.; Sweeney, Elizabeth A.; Tegreene, Clarence T.; Wood, Jr., Lowell L., Beverage containers with detection capability.
  2. Hood, Leroy E.; Jung, Edward K. Y.; Sweeney, Elizabeth A.; Tegreene, Clarence T.; Wood, Jr., Lowell L., Beverage immersate with detection capability.
  3. Tatum G. Roger ; Smith David J. ; Woodruff ; Jr. Charles ; Chang Connie, Device and method for automatic collection of whole saliva.
  4. Hood, Leroy E.; Jung, Edward K. Y.; Sweeney, Elizabeth A.; Tegreene, Clarence T.; Wood, Jr., Lowell L., Devices and methods for detecting an analyte in salivary fluid.
  5. Bodenhamer,William T., Displacement assay for selective biological material detection.
  6. Ligler, Frances S.; Kusterbeck, Anne W.; Rabbany, Sina Y., Displacement assay on a porous membrane.
  7. Ligler, Frances S.; Kusterbeck, Anne W.; Rabbany, Sina Y., Displacement assay on a porous membrane.
  8. Jonathan Stuart Wall, Flow cytometric characterization of amyloid fibrils.
  9. Fischer,Gerald Walter; Schuman,Richard F.; Wong,Hing; Stinson,Jeffrey R., Humanized and chimeric antibodies specific for lipoteichoic acid of GRAM positive bacteria.
  10. Smith, Dave; Smith, Mike; Tatum, Roger; Waltzer, Eric; Liang, Greg; Foley, Thomas J., Integral sample collection tip.
  11. Fischer,Gerald W., Isolated broadly reactive opsonic immunoglobulin for treating a pathogenic coagulase-negative staphylococcus infection.
  12. Chu,Victor P.; Teng,Zhu; Lewisch,Sandra; Edwards,Ronald L., Lidocaine analogs and methods of making and using same.
  13. Taylor, Palmer; Radic, Zoran; Shi, Jianxin; Boyd, Aileen, Ligand sensing fluorescent acetylcholinesterase for detection of organophosphate activity.
  14. Yager, Paul; Kosar, Turgut Fettah; Look, Michael Wai-Haung; Mashadi-Hossein, Afshin; McKenzie, Katherine; Nelson, Kjell E.; Spicar-Mihalic, Paolo; Stevens, Dean; Thariani, Rahber, Method and device for rapid parallel microfluidic molecular affinity assays.
  15. Wood Sheila J. ; Sydiskis Robert J., Method and kit for rapid detection of toxins and bacteria.
  16. Shipwash, Edward, Method and system for rapid biomolecular recognition of amino acids and protein sequencing.
  17. Johnson Ted Donald ; Brown W. Craig ; Kelly Raymond C., Method for forensically screening hair samples for the presence of cannabinoids.
  18. Johnson Ted Donald ; Brown W. Craig ; Kelly Raymond C., Method for forensically screening hair samples for the presence of cannabinoids.
  19. Maa Yuh-Fun ; Nguyen Phuong-Anh, Method of spray freeze drying proteins for pharmaceutical administration.
  20. Kinoshita,Takatoshi; Washizu,Shintaro, Molecular electric wire, molecular electric wire circuit using the same and process for producing the molecular electric wire circuit.
  21. Proniewicz, Walter K.; Winther, Dale E., Noninvasive measurement system.
  22. Stinson, Jeffrey R.; Schuman, Richard F.; Mond, James Jacob; Lees, Andrew; Fischer, Gerald Walter, Nucleic acids encoding opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria.
  23. Fischer, Gerald W.; Schuman, Richard F.; Wong, Hing; Stinson, Jeffrey R., Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram posiive bacteria.
  24. Fischer, Gerald W.; Schuman, Richard F.; Wong, Hing; Stinson, Jeffrey R., Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria.
  25. Fischer, Gerald W.; Schuman, Richard F.; Wong, Hing; Stinson, Jeffrey R., Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria.
  26. Stinson,Jeffrey R.; Schuman,Richard F.; Mond,James J.; Lees,Andrew; Fischer,Gerald Walter, Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria.
  27. Washizu,Shintaro; Matsunami,Yuki; Kinoshita,Takatoshi, Optical switch and safety apparatus using the same.
  28. Sattler, Stephan; Minemura, Yusuke; Yamaguchi, Takuya, Orientation identification label, reagent container carrier structure, analyzer device and reader module.
  29. Sattler, Stephan; Minemura, Yusuke; Yamaguchi, Takuya, Orientation identification label, reagent container carrier structure, analyzer device and reader module.
  30. Kinoshita,Takatoshi; Washizu,Shintaro, Particle size variable reactor.
  31. Fischer, Gerald Walter; Schuman, Richard F.; Wong, Hing; Stinson, Jeffrey R., Polynucleotides encoding humanized and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria.
  32. Inganas, Mats; Lindman, Susanna; Derand, Helene, Preloaded microfluidic devices.
  33. Duffy Geraldine,IEX ; Sheridan James,IEX, Rapid detection of bacteria liquid cultures.
  34. Bergmann, Andreas; Struck, Joachim, Receptor binding assay for detecting TSH-receptor auto-antibodies.
  35. Badley Robert A.,GBX ; Berry Mark J.,GBX ; Porter Philip,GBX ; Wattam Trevor A.,GBX, Specific binding assays.
  36. Washizu,Shintaro; Matsunami,Yuki; Kinoshita,Takatoshi, Target detecting apparatus, target detection method and target detection substrate.
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