초록 ▼

Systems and methods for separating a suspension of plasma and platelets from whole blood rotate a chamber about an axis to create within the chamber a low-G zone radially close to the axis and a high-G zone spaced radially further from the axis than the low-G zone. The systems and methods introduce

Systems and methods for separating a suspension of plasma and platelets from whole blood rotate a chamber about an axis to create within the chamber a low-G zone radially close to the axis and a high-G zone spaced radially further from the axis than the low-G zone. The systems and methods introduce whole blood into an inlet region of the chamber to initiate separation of red blood cells toward the high-G zone of the inlet region. This creates a strong flow of plasma that moves radially toward the low-G zone of the inlet region and elutes platelets into suspension with it. The systems and methods direct the radial flow of plasma and eluted platelets within the inlet region to a port in the inlet region for transport out of the chamber. The systems and methods also drag the interface into this radial plasma flow, eluting even the largest of platelets into suspension for collection.

대표청구항 ▼

A method for separating a suspension of plasma and platelets from whole blood comprising the steps of rotating a chamber about an axis to create within the chamber a low-G zone radially close to the axis and a high-G zone spaced radially further from the axis than the low-G zone, introducing whole b

A method for separating a suspension of plasma and platelets from whole blood comprising the steps of rotating a chamber about an axis to create within the chamber a low-G zone radially close to the axis and a high-G zone spaced radially further from the axis than the low-G zone, introducing whole blood into an inlet region of the chamber to initiate separation of red blood cells toward the high-G zone of the inlet region, thereby creating a flow of plasma that moves radially toward the low-G zone of the inlet region end elutes platelets into suspension with it, and directing the radial flow of plasma and eluted platelets within the inlet region to a port in the inlet region for transport out of the chamber at least in part while whole blood is introduced into, the inlet region.