초록 ▼

A new polymer, the feed monomers and molar percents of which, exclusive of a polymerization initiator and crosslinker, are: A. (I) 42 mole % to 58 mole % of a siloxy silane of formula I, (II) 42 mole % to 58 mole % of an unsubstituted alkyl (meth)acrylate of formula II, (III) 0 to 5 mole % of a Grou

A new polymer, the feed monomers and molar percents of which, exclusive of a polymerization initiator and crosslinker, are: A. (I) 42 mole % to 58 mole % of a siloxy silane of formula I, (II) 42 mole % to 58 mole % of an unsubstituted alkyl (meth)acrylate of formula II, (III) 0 to 5 mole % of a Group A monomer, and (IV) 0 to 16 mole % of an additional vinylic copolymerizable monomer; B. (I) 42 mole % to 58 mole % of a siloxy silane of formula I, (II) 21 mole % up to less than 42 mole % of an unsubstituted alkyl (meth)acrylate of formula II, (III) 0 to 5 mole % of a Group A monomer, and (IV) 0 to 29 mole % of an additional vinylic copolymerizable monomer; or C. (I) 16 mole % up to less than 42 mole % of a siloxy silane of formula I, (II) 42 mole % to 58 mole % of an unsubstituted alkyl (meth)acrylate of formula II, (III) 0 to 5 mole % of a Group A monomer, and (IV) 0 to 36 mole % of an additional vinylic copolymerizable monomer; where formula I is [Figure] (I) where formula II is [Figure] (II) in which R3 is hydrogen or methyl; and R4 is methyl or a linear or branched chain C2-10alkyl which is unsubstituted; where Group A is (meth)acrylic acid, maleic acid, fumaric acid, itaconic acid, itaconic acid, cinnamic acid, crotonic acid, fumaric acid, maleic acid, 2-(methy)acroyloxyethyl sulfonic acid, 2-(meth)acrylamido-2-methylpropane sulfonic acid, vinyl sulfonic acid, p-styrene sulfonioc acid, allyl sulfonic acid or of formula III.

대표청구항 ▼

A method of using a polymer as a transdermal or transmucosal drug delivery device pressure sensitive adhesive comprising incorporating said polymer into said device such that when said device is placed on the skin or mucosa of a user of said device, said polymer is in contact with said skin or mucos

A method of using a polymer as a transdermal or transmucosal drug delivery device pressure sensitive adhesive comprising incorporating said polymer into said device such that when said device is placed on the skin or mucosa of a user of said device, said polymer is in contact with said skin or mucosa and provides some or all of the adhesion of said device for said skin or mucosa, said polymer having a polymerization feed mixture of (a) an effective amount of a polymerization initiator, (b) 0 to 5 mole %, based on the total of all monomers present, of a vinylic copolymerizable crosslinker; and (c) one of the following groups (ii) or (iii); where (ii) is (I) 42 mole % to 58 mole % of a siloxy silane of formula I, (II) 21 mole % up to less than 42 mole % of an unsubstituted alkyl (meth)acrylate of formula II, (III) 0 to 5 mole % of a Group A monomer, and (IV) 0 to 29 mole % of an additional vinylic copolymerizable monomer of Group B; or where (iii) is (I) 16 mole % up to less than 42 mole % of a siloxy silane of formula I, (II) 42 mole % to 58 mole % of an unsubstituted alkyl (meth)acrylate of formula II, (III) 0 to 5 mole % of a Group A monomer, and (IV) 0 to 36 mole % of an additional vinylic copolymerizable monomer of Group B; in which formula I is [Figure] (I) in which R1 is hydrogen or methyl; R2 is alkylene of 1-6 carbon atoms; and n is an integer of from 0 to 2; and where formula II is [Figure] (II) in which R3 is hydrogen or methyl; and R4 is methyl or a linear or branched chain C2-10alkyl which is unsubstituted; and where Group A monomer is a monomer selected from the group consisting of (meth)acrylic acid, itaconic acid, cinnamic acid, crotonic acid, fumaric acid, maleic acid, 2-(methy)acroyloxyethyl sulfonic acid, 2-(meth)acrylamido-2-methylpropane sulfonic acid, vinyl sulfonic acid, p-styrene sulfonic acid, allyl sulfonic acid and monomers of formula III [Figure] (III) in which R5 is hydrogen or methyl; and R6 is a substituted linear or branched alkyl group of up to 10 carbon atoms, said substituent being selected from the group consisting of hydroxy, C1-4alkoxy, Cl, Br, F, carboxy, C1-4alkoxycarbonyl, C1-4alkylcarbonyloxy, and amino; and said additional vinylic copolymerizable monomer of Group B is neither a polymerization initiator, a crosslinker, nor a member of the group of compounds of formulae I, or II, nor a member of Group A monomers as defined above, but is a mono-unsaturated monomer which is copolymerizable with compounds of formulae I, II, and Group A monomers.