[특허]Iontophoretic delivery device and method of hydrating same

Iontophoretic delivery device and method of hydrating same 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61N-001/30
출원번호	US-0085466 (1993-06-30)
발명자 / 주소	Haak Ronald P. (San Jose CA) Gyory J. Richard (San Jose CA) Theeuwes Felix (Los Altos CA) Myers Robert M. (Stanford CA)
출원인 / 주소	Alza Corporation (Palo Alto CA 02)
인용정보	피인용 횟수 : 59 인용 특허 : 0

초록 ▼

A dry-state iontophoretic drug delivery device (10, 20) is provided. The device has drug and electrolyte reservoirs (15, 16) which are initially in a non-hydrated condition. In one embodiment of the invention, a passageway (21, 22) is provided through the backing layer (13) and the electrode layer (11, 12) of both the donor electrode assembly (8) and the counter electrode assembly (9). Water or other liquid can be introduced through these passageways (21, 22) in order to hydrate the drug and electrolyte reservoirs (15, 16) and activate the device (10). In another embodiment of the device (20), the drug and electrolyte reservoirs (15, 16) are initially separated from their respective electrodes (11, 12). After the reservoirs (15, 16) are hydrated, they are placed in electrical contact with their respective electrodes (11, 12). By joining the reservoir (15, 16) to the electrode (11, 12) after hydration occurs, delamination problems are reduced.

대표청구항 ▼

A multilaminate dry state electrode assembly for an electrically powered iontophoretic agent delivery device including a source of electrical power which is electrically connected to the electrode assembly, the electrode assembly including: a) a reservoir layer including a substantially non-hydrated hydratable matrix containing an agent to be delivered through a body surface; b) an electrode layer in electrical contact with both the reservoir layer and the power source; c) means for hydrating the substantially non-hydrated agent containing matrix, said means including a preformed sealable passageway through the electrode layer, the passageway when unsealed establishing fluid communication between the exterior of the device and the matrix, said means enabling a liquid from an external source to be introduced through the passageway and into the reservoir matrix in order to hydrate the matrix and activate the electrode assembly; and d) means for sealing the passageway after introducing the liquid therein.

이 특허를 인용한 특허 (59)

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