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Process for the preparation of biologically active material containing polymeric microcapsules 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/48
  • A61K-009/14
  • B01J-013/04
  • B01J-013/20
출원번호 US-0017925 (1993-02-16)
우선권정보 EP-0200466 (1992-02-18)
발명자 / 주소
  • Dirix Cardina A. M. C. (Westervoort NLX) Kamp Hendrikus J. M. (Westervoort NLX) Sam Anthonius P. (Heesch NLX)
출원인 / 주소
  • Akzo N.V. (Arnhem NLX 03)
인용정보 피인용 횟수 : 67  인용 특허 : 0

초록 ▼

A process for the preparation of microcapsules containing biologically active material is disclosed. The process involves dissolving a polymer into a solvent into which the active material is also introduced; atomizing the resulting suspension or solution and collecting the droplets in a non-solvent

대표청구항 ▼

A process for the preparation of polymeric microcapsules comprising a biologically active agent, said process comprising mixing an active agent with a solvent to form a solution or suspension, dissolving a polymer in a solvent, which may be the same solvent used for dissolving or suspending the acti

이 특허를 인용한 특허 (67)

  1. Leone-Bay Andrea ; Wang Eric ; Sarubbi Donald J. ; Leipold Harry ; Wang Nai Fang, 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents.
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  2. Milstein Sam J. ; Barantsevitch Evgueni ; Leone-Bay Andrea ; Wang Nai Fang ; Sarubbi Donald J. ; Santiago Noemi B, Active agent transport systems.
    상세보기
  3. Milstein Sam J. ; Barantsevitch Evgueni ; Leone-Bay Andrea ; Wang Nai Fang ; Sarubbi Donald J. ; Santiago Noemi B, Active agent transport systems.
    상세보기
  4. Milstein Sam J. ; Leone-Bay Andrea ; Sarubbi Donald J. ; Leipold Harry, Active agent transport systems.
    상세보기
  5. Milstein Sam J., Carbon-substituted diketopiperazine delivery systems.
    상세보기
  6. Kuo, Mei-chang; Lechuga-Ballesteros, David, Compositions comprising an active agent.
    상세보기
  7. Kuo,Mei chang; Lechuga Ballesteros,David, Compositions comprising an active agent.
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  8. Leone-Bay Andrea (Ridgefield CT) Ho Koc-Kan (Mt. Kisco NY) Press Jeffery Bruce (Brewster NY), Compositions for oral delivery of active agents.
    상세보기
  9. Santiago Noemi B. ; Haas Susan ; Leone-Bay Andrea, Compositions for the delivery of antigens.
    상세보기
  10. Santiago Noemi B. ; Haas Susan ; Leone-Bay Andrea ; Milstein Sam J. ; Barantsevitch Evgueni, Compositions for the delivery of antigens.
    상세보기
  11. Andrea Leone-Bay ; Koc-Kan Ho ; Donald J. Sarubbi ; Sam J. Milstein, Compounds and compositions for delivering active agents.
    상세보기
  12. Andrea Leone-Bay ; Koc-Kan Ho ; Donald J. Sarubbi ; Sam J. Milstein ; Nai Fang Wang, Compounds and compositions for delivering active agents.
    상세보기
  13. Leone Bay,Andrea; Milstein,Sam J.; Sarubbi,Donald J.; Leipold,Harry, Compounds and compositions for delivering active agents.
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  14. Leone-Bay Andrea (Ridgefield CT) Paton Duncan R. (Purdys NY) Ho Koc-Kan (Mt. Kisco NY) DeMorin Frenel (Spring Valley NY), Compounds and compositions for delivering active agents.
    상세보기
  15. Leone-Bay Andrea ; Gschneidner David ; Wang Eric ; Sarubbi Donald J., Compounds and compositions for delivering active agents.
    상세보기
  16. Leone-Bay Andrea ; Ho Koc-Kan ; Sarubbi Donald J. ; Leipold Harry R., Compounds and compositions for delivering active agents.
    상세보기
  17. Leone-Bay Andrea ; Ho Koc-Kan ; Sarubbi Donald J. ; Milstein Sam J., Compounds and compositions for delivering active agents.
    상세보기
  18. Leone-Bay Andrea ; Ho Koc-Kan ; Sarubbi Donald J. ; Milstein Sam J., Compounds and compositions for delivering active agents.
    상세보기
  19. Leone-Bay Andrea ; Ho Koc-Kan ; Sarubbi Donald J. ; Milstein Sam J., Compounds and compositions for delivering active agents.
    상세보기
  20. Leone-Bay Andrea ; Ho Koc-Kan ; Sarubbi Donald J. ; Milstein Sam J., Compounds and compositions for delivering active agents.
    상세보기
  21. Leone-Bay Andrea ; Paton Duncan R. ; Ho Koc-Kan ; DeMorin Frenel, Compounds and compositions for delivering active agents.
    상세보기
  22. Leone-Bay Andrea ; Paton Duncan R. ; Ho Koc-Kan ; DeMorin Frenel, Compounds and compositions for delivering active agents.
    상세보기
  23. Leone-Bay Andrea ; Wang Eric ; Sarubbi Donald J. ; Leipold Harry, Compounds and compositions for delivering active agents.
    상세보기
  24. Leone-Bay Andrea ; Wang Eric ; Sarubbi Donald J. ; Leipold Harry, Compounds and compositions for delivering active agents.
    상세보기
  25. Leone-Bay Andrea ; Wang Eric ; Sarubbi Donald J. ; Leipold Harry, Compounds and compositions for delivering active agents.
    상세보기
  26. Leone-Bay Andrea ; Wang Eric ; Sarubbi Donald J. ; Leipold Harry, Compounds and compositions for delivering active agents.
    상세보기
  27. Leone-Bay Andrea ; Wang Eric ; Sarubbi Donald J. ; Leipold Harry, Compounds and compositions for delivering active agents.
    상세보기
  28. Leone-Bay Andrea ; Wang Eric ; Sarubbi Donald J. ; Leipold Harry R., Compounds and compositions for delivering active agents.
    상세보기
  29. Leone-Bay Andrea ; Wang Eric Yanjun ; Sarubbi Donald J. ; Leipold Harry ; Wang Nai Fang, Compounds and compositions for delivering active agents.
    상세보기
  30. Leone-Bay, Andrea; Paton, Duncan R.; Ho, Koc-Kan; DeMorin, Frenel, Compounds and compositions for delivering active agents.
    상세보기
  31. Sarubbi, Donald J.; Barantsevitch, Eugene N., Compounds and compositions for delivering active agents.
    상세보기
  32. Sarubbi, Donald J.; Barantsevitch, Evgueni, Compounds and compositions for delivering active agents.
    상세보기
  33. Thanoo Bagavathikanun Chithambara ; Murtagh James, Continuous microsphere process.
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  34. Milstein Sam J. ; Barantsevitch Evgueni N., Desferrioxamine oral delivery system.
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  35. Milstein Sam J., Diketopiperazine-based delivery systems.
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  36. Milstein Sam J. (Larchmont NY), Diketopiperazine-based delivery systems.
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  37. Babaev, Eilaz, Echoing ultrasound atomization and/or mixing system.
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  38. Cady,Susan Mancini; Macar,Claude; Gibson,John W., Extended release growth promoting two component composition.
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  39. Susan Mancini Cady ; Claude Macar FR; John W. Gibson, Extended release growth promoting two component composition.
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  40. Milstein Sam J., Fragrances and flavorants.
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  41. Bagavathikanun Chithambara Thanoo ; James Murtagh, Method and apparatus for formulating microspheres and microcapsules.
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  42. Thanoo Bagavathikanun Chithambara ; Murtagh James, Method and apparatus for formulating microspheres and microcapsules.
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  43. Ho Koc-Kan ; Leone-Bay Andrea, Method for preparing .omega.-aminoalkanoic acid derivatives from cycloalkanones.
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  44. Gschneidner David ; O'Toole Doris ; Freeman John, Method of preparing salicyloylamino acids.
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  45. Martin L. Kantor, Method of solubilizing and encapsulating itraconazole.
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  46. Kantor Martin L., Method of solubilizing itraconazole.
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  47. Susan Haas ; Sam J. Milstein, Methods and compositions for inducing oral tolerance in mammals.
    상세보기
  48. Martin L. Kantor ; Evgueni Barantsevitch ; Sam J. Milstein, Microencapsulated fragrances and method for preparation.
    상세보기
  49. Park, Kinam; Yeo, Yoon, Microencapsulation using ultrasonic atomizers.
    상세보기
  50. Milstein Sam J., Microspheres of diamide-dicarboxylic acids.
    상세보기
  51. Leone-Bay Andrea ; Ho Koc-Kan ; Press Jeffery Bruce ; Wang Nai-Fang, Modified amino acids and compositions comprising the same for delivering active agents.
    상세보기
  52. Leone-Bay Andrea (Ridgefield CT) Wang Nai F. (Long Island City NY), Modified amino acids for drug delivery.
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  53. Leone-Bay Andrea ; Wang Nai Fang, Modified amino acids for drug delivery.
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  54. Leone-Bay Andrea ; Wang Nai Fang, Modified amino acids for drug delivery.
    상세보기
  55. Milstein Sam J. ; Barantsevitch Evgueni N., Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof.
    상세보기
  56. Milstein Sam J. ; Barantsevitch Evgueni ; Leone-Bay Andrea ; Wang Nai Fang ; Sarubbi Donald J. ; Santiago Noemi B, Oral delivery composition comprising supramolecular complex.
    상세보기
  57. Sarubbi Donald J. ; Leone-Bay Andrea ; Paton Duncan R., Oral drug delivery compositions and methods.
    상세보기
  58. Sam J. Milstein ; Evgueni Barantsevitch ; Andrea Leone-Bay ; Nai Fang Wang ; Donald J. Sarubbi ; Noemi B Santiago, Orally deliverable supramolecular complex.
    상세보기
  59. Ramstack J. Michael (Lebanon OH) Herbert Paul F. (Wayland MA) Strobel Jan (Westchester OH) Atkins Thomas J. (Cincinnati OH), Preparation of biodegradable microparticles containing a biologically active agent.
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  60. Milstein Sam J. (Larchmont NY) Kantor Martin L. (Mamaroneck NY), Proteinoid carriers and methods for preparation and use thereof.
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  61. Sam J. Milstein ; Martin L. Kantor, Proteinoid carriers and methods for preparation and use thereof.
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  62. Kantor Martin L., Proteinoid emulsions and methods for preparation and use thereof.
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  63. Milstein Sam J. (Brooklyn NY) Kantor Martin L. (Mamaroneck NY), Proteinoid microspheres and methods for preparation and use thereof.
    상세보기
  64. Kantor Martin L. (Mamaroneck NY), Spray drying method and apparatus.
    상세보기
  65. Babaev, Eilaz, Ultrasonic atomization and/or seperation system.
    상세보기
  66. Babaev, Eilaz P., Ultrasound apparatus and methods for mixing liquids and coating stents.
    상세보기
  67. Babaev, Eilaz, Ultrasound pumping apparatus.
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