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Liposomes as contrast agents for ultrasonic imaging 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-008/08
출원번호 US-0395683 (1995-02-28)
발명자 / 주소
  • Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749)
인용정보 피인용 횟수 : 15  인용 특허 : 68

초록 ▼

Liposomes suitable as ultrasound contrast agents which contain media of various types including gases, gaseous precursors activated by pH, temperature or pressure, as well as other solid or liquid contrast enhancing agents, are described. Methods of using the same as ultrasound contrast agents are a

대표청구항 ▼

A method of providing an image of an internal region of a patient comprising: (a) administering to the patient a liposome having encapsulated therein a solid contrast enhancing agent selected from the group consisting of magnetite and solid iodine particles, or a liquid contrast enhancing agent sele

이 특허에 인용된 특허 (68)

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  30. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same.
    상세보기
  31. Ryan, Patrick J.; Davis, Michael A.; Melchior, Donald L., Liposomes containing modified cholesterol for organ targeting.
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  40. Barenholz Yechezkel (Jerusalem ILX) Haran Gilad (Jerusalem ILX), Method of amphiphatic drug loading in liposomes by ammonium ion gradient.
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  41. Bonsen Pieter (Los Altos CA) Wong Patrick S. (Kowloon CA HKX) Theeuwes Felix (Los Altos CA), Method of delivering drug with aid of effervescent activity generated in environment of use.
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  49. Schneider Michel (Grand-Lancy CHX) Lamy Bernard (Carouge CHX), Process for the dehydration of a colloidal dispersion of lipsomes.
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  54. Farmer Martha C. (Washington DC) Beissinger Richard L. (Oak Park IL), Scaled-up production of liposome-encapsulated hemoglobin.
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  57. Payne Nicholas I. (Wirral GBX) Salmon J. Roger (Wirral GBX), Spray-drying method for preparing liposomes and products produced thereby.
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  68. Carson Paul L. (Ann Arbor MI) Detsch Richard M. (Denver CO), Variable frequency gas-bubble-manipulating apparatus and method.
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이 특허를 인용한 특허 (15)

  1. Quay Steven C., Colloidal dispersions of perfluoropentane.
    상세보기
  2. Quay Steven C., Gaseous ultrasound contrast media and method for selecting gases for use as ultrasound contrast media.
    상세보기
  3. Robinson, Simon P.; Siegler, Robert W.; Onthank, David C.; Nguyen, Nhung Tuyet, Lipid-encapsulated gas microsphere compositions and related methods.
    상세보기
  4. Madsen Ernest L. ; Frank Gary R., Method of making a solid tissue mimicking material for ultrasound phantoms.
    상세보기
  5. Robinson, Simon P.; Siegler, Robert W.; Nguyen, Nhung Tuyet; Onthank, David C.; Anklekar, Tarakeshwar Vishwanath; Van Kirk, Charles Chester, Methods for making ultrasound contrast agents.
    상세보기
  6. Robinson, Simon P.; Siegler, Robert W.; Nguyen, Nhung Tuyet; Onthank, David C.; Anklekar, Tarakeshwar Vishwanath; Van Kirk, Charles Chester, Methods for making ultrasound contrast agents.
    상세보기
  7. Robinson, Simon P.; Siegler, Robert W.; Nguyen, Nhung Tuyet; Onthank, David C.; Anklekar, Tarakeshwar Vishwanath; Van Kirk, Charles Chester, Methods for making ultrasound contrast agents.
    상세보기
  8. Hui, Poh K.; Bishop, John E.; Madrigal, Jr., Eleodoro S., Preparation of a lipid blend and a phospholipid suspension containing the lipid blend.
    상세보기
  9. Hui, Poh K.; Bishop, John E.; Madrigal, Jr., Eleodoro S., Preparation of a lipid blend and a phospholipid suspension containing the lipid blend.
    상세보기
  10. Hui, Poh K.; Bishop, John E.; Madrigal, Jr., Eleodoro S., Preparation of a lipid blend and a phospholipid suspension containing the lipid blend.
    상세보기
  11. Hui, Poh K.; Bishop, John E.; Madrigal, Jr., Eleodoro S., Preparation of a lipid blend and a phospholipid suspension containing the lipid blend.
    상세보기
  12. Walovitch, Richard; Bernstein, Howard; Chickering, Donald; Straub, Julie, Ultrasound contrast agent dosage formulation.
    상세보기
  13. Walovitch, Richard; Bernstein, Howard; Chickering, III, Donald; Straub, Julie, Ultrasound contrast agent dosage formulation.
    상세보기
  14. Dees,H. Craig; Scott,Timothy C.; Wachter,Eric A., Ultrasound contrast using halogenated xanthenes.
    상세보기
  15. Madsen Ernest L. (Madison WI) Frank Gary R. (Madison WI), Very low scatter liquid and solid tissue mimicking material for ultrasound phantoms and method of making the same.
    상세보기

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