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Device and method for analysis of blood components and identifying inhibitors and promoters of the inflammatory response 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-005/00
  • C12Q-001/02
  • G01N-033/566
출원번호 US-0887444 (1992-05-20)
발명자 / 주소
  • Springer Timothy A. (Chestnut Hill MA) Lawrence Michael (Brookline MA)
출원인 / 주소
  • Center for Blood Research, Inc. (Boston MA 02)
인용정보 피인용 횟수 : 94  인용 특허 : 0

초록 ▼

The present invention provides in vitro models of the in vivo rolling and arrest of leukocytes along the endothelial cell wall, which are important steps in the migration of leukocytes out of the blood stream and into tissue, as part of the inflammatory response. The in vitro models of the invention

대표청구항 ▼

An apparatus comprising (a) a solid phase having at least one surface containing a plurality of one or more substantially purified molecules, said molecules being capable of mediating rolling of a leukocyte on the solid phase surface; (b) a housing enclosing the solid phase, said housing having an i

이 특허를 인용한 특허 (94)

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