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Microdelivery device and method for enhanced drug administration to the eye 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/00
출원번호 US-0244248 (1994-11-02)
우선권정보 IL-0100112 (1991-11-21)
국제출원번호 PCT/US92/09878 (1992-11-16)
§371/§102 date 19941102 (19941102)
국제공개번호 WO-9309829
발명자 / 주소
  • Dan Jacov (Hod Hasharon ILX) Yaron Arieh (Rehovot ILX)
출원인 / 주소
  • Yeda Research and Development Co., Ltd. (Rehovot ILX 03)
인용정보 피인용 횟수 : 62  인용 특허 : 0

초록

A device for pinpoint application of micro-quantities of a pharmacologically suitable composition to the outer hard coat of the eye, comprises a micro-container with a fixation element. The micro-container comprises a bore whose aperture is adapted to contact the eye surface, and the fixation elemen

대표청구항

A device for pinpoint application of micro-quantities of a pharmaceutical composition to a preselected portion of the outer hard coat of the eye, the device comprising a micro-container with fixation means for reversible attachment of said micro-container to the outer hard coat of the eye adjacent t

이 특허를 인용한 특허 (62)

  1. Van Dalen,Johan T. W., Apparatus and method for delivering controlled quantities of one or more agents to the eye.
  2. Humayun, Mark S.; Caffey, Sean, Apparatus and methods for delivering therapeutic agents.
  3. Humayun, Mark S.; Caffey, Sean, Apparatus and methods for delivering therapeutic agents.
  4. Humayun, Mark; Caffey, Sean, Apparatus and methods for delivering therapeutic agents.
  5. Sabatino, Gregory L.; Del Tito, Jr., Benjamin J.; Bassett, Phillip J.; Tharia, Hazel A.; Hitchcock, Antony G., Compositions and methods for treating collagen-mediated diseases.
  6. Pallikaris, Ioannis; Ginis, Harilaos S., Device for separating the epithelium layer from the surface of the cornea of an eye.
  7. Pallikaris, Ioannis; Ginis, Harilaos S., Device for separating the epithelium layer from the surface of the cornea of an eye.
  8. Pallikaris,Ioannis; Ginis,Harilaos S., Device for separating the epithelium layer from the surface of the cornea of an eye.
  9. Pallikaris,Ioannis; Ginis,Harilaos S., Device for separating the epithelium layer from the surface of the cornea of an eye.
  10. Clauson, Luke; Silvestrini, Thomas A.; Ianchulev, Tsontcho; John, Steven, Drug delivery devices and methods.
  11. Clauson, Luke; Silvestrini, Thomas A.; Ianchulev, Tsontcho; John, Steven, Drug delivery devices and methods.
  12. Clauson, Luke; Silvestrini, Thomas A.; Ianchulev, Tsontcho; John, Steven, Drug delivery devices and methods.
  13. Shih, Jason; Brennan, Jeffrey; Jiang, Fukang; Caffey, Sean, Drug-delivery pump with dynamic, adaptive control.
  14. Li, Po-Ying; Li, Shengtao; Lee, Jonathan K.; Ryan, Patrick; Lai, Alice; Caffey, Sean; Humayun, Mark S., Drug-delivery pump with intelligent control.
  15. Li, Po-Ying; Li, Shengtao; Lee, Jonathan K.; Ryan, Patrick; Lai, Alice; Caffey, Sean; Humayun, Mark S., Drug-delivery pump with intelligent control.
  16. Pang, Changlin; Jiang, Fukang; Shih, Jason; Caffey, Sean; Humayun, Mark S.; Tai, Yu-Chong, Drug-delivery pumps and methods of manufacture.
  17. Pang, Changlin; Jiang, Fukang; Shih, Jason; Caffey, Sean; Humayun, Mark S.; Tai, Yu-Chong, Drug-delivery pumps and methods of manufacture.
  18. Pang, Changlin; Jiang, Fukang; Shih, Jason; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong, Drug-delivery pumps and methods of manufacture.
  19. Pang, Changlin; Jiang, Fukang; Shih, Jason; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong, Drug-delivery pumps and methods of manufacture.
  20. Pang, Changlin; Jiang, Fukang; Shih, Jason; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong, Drug-delivery pumps and methods of manufacture.
  21. Pang, Changlin; Jiang, Fukang; Shih, Jason; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong, Drug-delivery pumps and methods of manufacture.
  22. Pang, Changlin; Jiang, Fukang; Shih, Jason; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong; Brennan, Jeffrey; Peck, Raymond, Drug-delivery pumps and methods of manufacture.
  23. Shih, Jason; Brennan, Jeffrey; Jiang, Fukang; Caffey, Sean, Drug-delivery pumps with dynamic, adaptive control.
  24. Charles, Matthew, Formulations of human tissue kallikrein-1 for parenteral delivery and related methods.
  25. Charles, Matthew; Kolodka, Tadeusz; Williams, Mark, Human tissue kallikrein 1 glycosylation isoforms.
  26. Charles, Matthew; Kolodka, Tadeusz; Williams, Mark, Human tissue kallikrein 1 glycosylation isoforms.
  27. Humayun, Mark; Tai, Yu-Chong; Jelisavcic, Nenad; Kavazov, Julian D.; Jiang, Fukang, Implantable drug pumps and refill devices therefor.
  28. Tai, Yu-Chong; Shih, Jason; Kavazov, Julian D., Implantable drug pumps and refill devices therefor.
  29. Shih, Jason; Pang, Changlin; Jiang, Fukang; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong; Peck, Raymond, Implantable drug-delivery devices, and apparatus and methods for filling the devices.
  30. Shih, Jason; Pang, Changlin; Jiang, Fukang; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong; Peck, Raymond, Implantable drug-delivery devices, and apparatus and methods for filling the devices.
  31. Shih, Jason; Tai, Yu-Chong; Pang, Changlin; Caffey, Sean; Peck, Raymond; Jiang, Fukang; Humayun, Mark, Implantable drug-delivery devices, and apparatus and methods for filling the devices.
  32. Meng, Ellis Fan-chuin; Humayun, Mark S.; Lo Mann, Ronalee; Li, Po-Ying; Saati, Saloomeh, Implantable drug-delivery devices, and apparatus and methods for refilling the devices.
  33. Caffey, Sean; Jiang, Fukang; Pang, Changlin; Shih, Jason; Brennan, Jeffrey; Peck, Raymond; Journey, Michelle, Implantable drug-delivery pump.
  34. Meng, Ellis Fan-chuin; Chen, Po-Jui; Rodger, Damien C.; Tai, Yu-Chong; Humayun, Mark S., Implantable intraocular pressure drain.
  35. Pang, Changlin; Shih, Jason; Jiang, Fukang; Caffey, Sean; Humayun, Mark; Tai, Yu-Chong, Implantable pumps and cannulas therefor.
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  37. Myers, Raymond I, Laser methods for creating an antioxidant sink in the crystalline lens for the maintenance of eye health and physiology and slowing presbyopia development.
  38. Myers, Raymond I, Laser methods for creating an antioxidant sink in the crystalline lens for the maintenance of eye health and physiology and slowing presbyopia development.
  39. Naranjo-Tackman, Ramón; Kuri, Jorge Octavio Villar; Frey, Rudolph W., Laser system and method for astigmatic corrections in association with cataract treatment.
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  42. Bott, Steven E.; Frey, Rudolph W.; Porter, Gerrit N.; Wakefield, Scott Howard; Chura, William D., Laser system for treatment of the eye.
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  44. Myers, Raymond I., Lenticular refractive surgery of presbyopia, other refractive errors, and cataract retardation.
  45. Frey, Rudolph W.; Bott, Steven E.; Porter, Gerrit N., Liquid filled index matching device for ophthalmic laser procedures.
  46. Meng, Ellis; Tai, Yu-Chong; Humayun, Mark S.; Agrawal, Rajat; Lo, Ronalee; Shih, Jason; Kuwahara, Kenrick; Li, Po-Ying; Rodger, Damien; Chen, Po-Jui, MEMS device and method for delivery of therapeutic agents.
  47. Meng, Ellis; Tai, Yu-Chong; Humayun, Mark; Agrawal, Rajat; Lo, Ronalee; Shih, Jason; Kuwahara, Kenrick; Li, Po-Ying; Rodger, Damien; Chen, Po-Jui, MEMS device and method for delivery of therapeutic agents.
  48. Tai, Yu-Chong; Humayun, Mark; Shih, Jason, MEMS device and method for delivery of therapeutic agents.
  49. Tai, Yu-Chong; Humayun, Mark; Shih, Jason, MEMS device and method for delivery of therapeutic agents.
  50. Greenberg Robert J. ; Schulman Joseph H., Method and apparatus for intraocular retinal tack inserter.
  51. Frey, Rudolph W.; Gray, Gary P., Method and system for measuring an eye.
  52. Frey, Rudolph W.; Gray, Gary P., Method and system for removal and replacement of lens material from the lens of an eye.
  53. Jiang, Ching-Chuan; Liao, Chun-Jen; Chang, Wen-Hsiang; Chen, Huang-Chi; Liao, Wei-Ju; Wang, Wen-Hsi, Method for enzymatic treatment, device and kit used the same.
  54. Jiang, Ching-Chuan; Liao, Chun-Jen; Chang, Wen-Hsiang; Chen, Huang-Chi; Liao, Wei-Ju; Wang, Wen-Hsi, Method for enzymatic treatment, device and kit used the same.
  55. Frey, Rudolph W.; Bott, Steven E., Purkinjie image-based alignment of suction ring in ophthalmic applications.
  56. Frey, Rudolph W.; Gray, Gary P.; Zepkin, Neil; Downes, Jr., George R.; De Castro, Jorge A.; Kuszak, Jerome R.; Olmstead, Richard Ty, System and apparatus for delivering a laser beam to the lens of an eye.
  57. Frey, Rudolph W.; Gray, Gary P.; Pape, Dennis R.; Downes, Jr., George R.; De Castro, Jorge A.; Kuszak, Jerome R., System and apparatus for treating the lens of an eye.
  58. Frey, Rudolph W.; Gray, Gary P.; Kuszak, Jerome R., System and method for improving the accommodative amplitude and increasing the refractive power of the human lens with a laser.
  59. Frey, Rudolph W.; Gray, Gary P.; Zepkin, Neil, System and method for performing LADAR assisted procedures on the lens of an eye.
  60. Frey, Rudolph W.; Bott, Steven E.; Gray, Gary P., System and method for providing laser shot patterns to the lens of an eye.
  61. Frey, Rudolph W.; Gray, Gary P.; Pape, Dennis R.; Subramaniam, Hari; Kuszak, Jerome R., System and method for providing the shaped structural weakening of the human lens with a laser.
  62. Frey, Rudolph W.; Olmstead, Richard Ty; Gray, Gary P.; Bott, Steven E.; Strobel, James, System and method of scan controlled illumination of structures within an eye.
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