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Semipermeable microspheres encapsulating biological material

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-011/00
  • C12N-011/16
  • C12N-011/18
출원번호 US-0126787 (1993-09-23)
발명자 / 주소
  • Wang Taylor G. (Nashville TN)
출원인 / 주소
  • Vanderbilt University (Nashville TN 02)
인용정보 피인용 횟수 : 63  인용 특허 : 0

초록

Microspheres of a substantially uniform diameter are produced having a central portion composed of a solution of a polyanion containing a biological material, and an outer permeable membrane enclosing the central portion which is a complex of the polyanion and a polycation. The biological material h

대표청구항

Semipermeable microspheres encapsulating biological material, comprising microspheres of substantially uniform diameter within the range from 200 microns to 2 millimeters, said microspheres having a central portion composed of a solution of a polyanion containing a biological material of molecular s

이 특허를 인용한 특허 (63)

  1. Hunter William L.,CAX ; Machan Lindsay S.,CAX ; Arsenault A. Larry,CAX, Anti-angiogenic compositions and methods of use.
  2. Hunter William L.,CAX ; Machan Lindsay S.,CAX ; Arsenault A. Larry,CAX, Anti-angiogenic compositions and methods of use.
  3. Hunter, William L.; Machan, Lindsay S.; Arsenault, A. Larry, Anti-angiogenic compositions and methods of use.
  4. Hunter, William L.; Machan, Lindsay S.; Arsenault, A. Larry, Anti-angiogenic compositions and methods of use.
  5. Yu, Hanry; Ho, Hai Ting; Zhang, Jing, Apparatus for encapsulating cells.
  6. Razavi-Shirazi, Fatemeh; Dorri, Mohammad Ali; Dorri-Nowkoorani, Farhad; Razavi, Ameen(nmn), Biocatalyst compositions and processes for their use.
  7. Razavi-Shirazi, Fatemeh; Dorri, Mohammad Ali; Razavi, Ameen, Bioconversion processes using water-insoluble liquids.
  8. Kiser, Patrick F.; Thomas, Allen A., Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments.
  9. Razavi-Shirazi, Fatemeh; Razavi, Ameen, Bioprocesses for making butanol.
  10. Wang,Da Ming; Lai,Juin Yig; Lee,Kueir Rarn; Kuo,Pei Yun; Su,Yu Huei, Chitosan membrane containing nano-inorganic particles and the method for forming the same.
  11. Frampton Harry (West Yorkshire GBX), Downhole fluid control processes.
  12. Shanley,John F.; Parker,Theodore L., Drug delivery device and method for bi-directional drug delivery.
  13. Ales Prokop, Drug delivery system exhibiting permeability control.
  14. Prokop, Ales, Drug delivery system exhibiting permeability control.
  15. Kim, Kyekyoon; Singh, Ravindra Pratap, Electrohydrodynamic spraying system.
  16. Razavi-Shirazi, Fatemeh; Razavi, Ameen; Balmer, Norman Louis, Enhanced efficiency ethanol and sugar conversion processes.
  17. Shanley, John F., Expandable medical device delivery system and method.
  18. Shanley, John F., Expandable medical device for delivery of beneficial agent.
  19. Shanley, John F., Expandable medical device for delivery of beneficial agent.
  20. Shanley, John F., Expandable medical device for delivery of beneficial agent.
  21. Shanley, John F.; Eigler, Neal L.; Park, Kinam; Edelman, Elazer R., Expandable medical device for delivery of beneficial agent.
  22. Shanley, John F.; Eigler, Neal L.; Park, Kinam; Edelman, Elazer R., Expandable medical device for delivery of beneficial agent.
  23. Shanley,John F., Expandable medical device for delivery of beneficial agent.
  24. Shanley,John F.; Eigler,Neal L.; Park,Kinam; Edelman,Elazer R., Expandable medical device for delivery of beneficial agent.
  25. Shanley, John F., Expandable medical device with S-shaped bridging elements.
  26. Shanley, John F., Expandable medical device with beneficial agent concentration gradient.
  27. Shanley, John F., Expandable medical device with beneficial agent delivery mechanism.
  28. Shanley, John F., Expandable medical device with beneficial agent delivery mechanism.
  29. Shanley, John F., Expandable medical device with beneficial agent delivery mechanism.
  30. Shanley, John F., Expandable medical device with ductile hinges.
  31. Shanley, John F., Expandable medical device with ductile hinges.
  32. Shanley, John F., Expandable medical device with ductile hinges.
  33. Shanley, John F.; Eigler, Neal L.; Edelman, Elazer R., Expandable medical device with improved spatial distribution.
  34. Shanley, John F., Expandable medical device with tapered hinge.
  35. Ide, Katsuya; Hiruma, Kei, Gel manufacturing apparatus.
  36. Wang I-fan, Highly asymmetric anionic membranes.
  37. Shanley, John F.; Parker, Theodore L.; Park, Kinam, Implantable medical device with beneficial agent concentration gradient.
  38. Shanley,John F.; Parker,Theodore L., Implantable medical device with drug filled holes.
  39. Vol, Alexander; Gribova, Orna, Matrix carrier compositions, methods and uses.
  40. Vol, Alexander; Gribova, Orna, Matrix carrier compositions, methods and uses.
  41. Diaz, Stephen Hunter; Park, Kinam, Method and apparatus for loading a beneficial agent into an expandable medical device.
  42. Diaz, Stephen Hunter; Park, Kinam, Method and apparatus for loading a beneficial agent into an expandable medical device.
  43. Shanley, John F.; Diaz, Stephen Hunter, Method and apparatus for loading a beneficial agent into an expandable medical device.
  44. Marfurt,Karen L., Method and test strip for determining a fluid analyte.
  45. Opara Emmanuel C., Method of culturing, cryopreserving and encapsulating pancreatic islet cells.
  46. Dunfield, John Stephen; Ayres, James W., Method of making microcapsules utilizing a fluid ejector.
  47. Vol, Alexander; Gribova, Orna, Methods and compositions for oral administration of protein and peptide therapeutic agents.
  48. Vol, Alexander; Gribova, Orna, Methods and compositions for oral administration of protein and peptide therapeutic agents.
  49. Emmanuel C. Opara, Methods of culturing and encapsulating pancreatic islet cells.
  50. Prokop, Ales, Micro-particulate and nano-particulate polymeric delivery system.
  51. Opara, Emmanuel C., Microencapsulated pancreatic islet cells.
  52. Kim, Kyekyoon; Choi, Hyungsoo; Choy, Young Bin, Microparticles.
  53. Kim,Kyekyoon; Choi,Hyungsoo; Choy,Young Bin, Microparticles.
  54. Cristiano, Richard J.; Yamashita, Motoyuki, PEI: DNA vector formulations for in vitro and in vivo gene delivery.
  55. Berlin Mikael (Lund SEX) Lundgren Bo (Kavlinge SEX), Packaging laminate and a method of producing the same.
  56. Blackburn,William P.; Levesque,Michael B.; Seybert,Kevin W.; Conklin,Jeanine A.; Gruchacz,Nancyanne, Photochromic optical article.
  57. Blackburn,William P.; Levesque,Michael B.; Stewart,Kevin J.; Short,Cathy L., Photochromic optical article.
  58. King, Eric M., Photochromic optical article.
  59. King,Eric M., Photochromic optical article.
  60. Knox,Carol L.; King,Eric M.; Colton,James P., Photochromic optical article.
  61. Walsh, Stephen E.; Canfield, Monte R.; Drake, Nancy J., System and method for encapsulating biological material by applying electrostatic charge to capsules.
  62. Shanley, John F.; Parker, Theodore L., Therapeutic agent delivery device with controlled therapeutic agent release rates.
  63. Shanley,John F.; Parker,Theodore L., Therapeutic agent delivery device with controlled therapeutic agent release rates.
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