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Benzothiophene compounds intermediate compositions and methods for inhibiting aortal smooth muscle proliferation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/445
  • A61K-031/535
  • A61K-031/55
  • A61L-031/40
출원번호 US-0469952 (1995-06-06)
발명자 / 주소
  • Palkowitz Alan D. (Carmel IN)
출원인 / 주소
  • Eli Lilly and Company (Indianapolis IN 02)
인용정보 피인용 횟수 : 58  인용 특허 : 0

초록 ▼

The present invention provides pharmaceutically active compounds of formula I [Figure] I wherein R1 is －H, －OH, －O(C1-C4 alkyl), －OCOC6H5, －OCO(C1-C6 alkyl), or －OSO2(C2-C6 alkyl); R2 is －H, －OH, －O(C1-C4 alkyl), －OCOC6H5, －OCO(C1-C6 alkyl), －OSO2(C2-C6 alkyl), or halo, providing when Z is －S－, R2 i

대표청구항 ▼

A method for inhibiting aortal smooth muscle cell proliferation comprising administering to a human in need of treatment an effective amount of a compound of formula I [Figure] I wherein R1 is －H, －OH, －O(C1-C4 alkyl), －OCOC6H5, －OCO(C1-C6 alkyl), or －OSO2(C2-C6 alkyl); R2 is －H, －OH, －OC1-C4 alkyl)

이 특허를 인용한 특허 (58)

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