[특허]Centrifugation pheresis system

Centrifugation pheresis system 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	B01D-021/26 B04B-007/00 B04B-007/08
출원번호	US-0199082 (1994-02-22)
발명자 / 주소	Brown Richard I. (Northbrook IL) Smith Sidney (Lake Forest IL) Cerny David E. (Crystal Lake IL) Foley John T. (Wheeling IL)
출원인 / 주소	Baxter International Inc. (Deerfield IL 02)
인용정보	피인용 횟수 : 119 인용 특허 : 0

초록 ▼

A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis. The platelet rich plasma is separated from the residual red blood cells in a first part. The platelet rich plasma flows into the second part and is separated into platelet poor plasma and platelets. The platelet poor plasma can be drawn off and returned to a donor or collected. The platelet concentrate can then be accumulated in a separate container.

대표청구항 ▼

A chamber for use in a rotating field to separate whole blood into red blood cells and a plasma constituent comprising wall means for defining first and second radially spaced apart walls forming a separation zone, the first wall comprising a low-G side of the separation zone located a first radial distance from the rotational axis, the second wall comprising a high-G side of the separation zone located a second radial distance from the rotational axis are greater than the first radial distance, the the separation zone including an inlet region, a first port in the inlet region for conveying whole blood into the inlet region in a first flow direction to begin separation into red blood cells toward the high-G side of the separation zone and the plasma constituent toward the low-G side of the separation zone, a second port on the high-G side of the inlet region for collecting red blood cells from the high-G side of the separation zone, and the separation zone being free of slope along the axis of rotation in the first flow direction, the second radial distance of the second wall from the rotational axis decreasing in the first flow direction from the inlet region while the radial spacing between the first and second walls decreases in the first flow direction in the inlet region forming a tapered ramp in the inlet region for urging red blood cells along the high-G side to flow toward the second port in a second flow direction opposite to the first flow direction.

이 특허를 인용한 특허 (119)

Leach, Michael D.; Chavarria, Jason, All-in-one means of separating blood components.
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Leach, Michael D.; Chavarria, Jason, All-in-one means of separating blood components.
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Dorian, Randel; Leach, Michael D., Apparatus and method for preparing platelet rich plasma and concentrates thereof.
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Dorian, Randel; Leach, Michael D., Apparatus and method for preparing platelet rich plasma and concentrates thereof.
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Dorian, Randel; Leach, Michael D., Apparatus and method for preparing platelet rich plasma and concentrates thereof.
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Higgins, Joel C.; Leach, Michael D.; Woodell-May, Jennifer E.; Miller, Brandon, Apparatus and method for separating and concentrating fluids containing multiple components.
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Higgins, Joel C.; Swift, Matthew; Gordon, Nathan; Hecker, Barry F., Apparatus and method for separating and concentrating fluids containing multiple components.
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Higgins, Joel C.; Swift, Matthew; Gordon, Nathan; Hecker, Barry F., Apparatus and method for separating and concentrating fluids containing multiple components.
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Landrigan, Matthew D.; Leach, Michael D.; Higgins, Joel C., Apparatus and method for separating and concentrating fluids containing multiple components.
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Landrigan, Matthew D.; Leach, Michael D.; Higgins, Joel C., Apparatus and method for separating and concentrating fluids containing multiple components.
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Landrigan, Matthew D.; Swift, Matthew, Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach, Michael D.; Higgins, Joel C., Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach, Michael D.; Higgins, Joel C., Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach, Michael D.; Higgins, Joel C.; Swift, Matthew; Gordon, Nathan, Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach, Michael D.; Higgins, Joel C.; Swift, Matthew; Gordon, Nathan, Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach, Michael D.; Woodell-May, Jennifer E.; Higgins, Joel C.; Miller, Brandon, Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach, Michael D.; Woodell-May, Jennifer E.; Higgins, Joel C.; Miller, Brandon, Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach,Michael; Woodell May,Jennifer E.; Higgins,Joel, Apparatus and method for separating and concentrating fluids containing multiple components.
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Leach,Michael; Woodell May,Jennifer E.; Higgins,Joel C.; Miller,Brandon, Apparatus and method for separating and concentrating fluids containing multiple components.
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Woodell-May, Jennifer E., Apparatus and method for separating and concentrating fluids containing multiple components.
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Briggs,Dennis; Gara,Steve; Watters,Tom; Hutchinson,Mike, Apparatus for the continuous separation of biological fluids into components and method of using same.
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Attila, Mady, Apparatus to assist platelet manipulation to prevent and treat endovascular disease and its sequelae.
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Dolecek,Victor D.; Malcolm,David, Blood centrifuge having clamshell blood reservoir holder with index line.
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Dolecek, Victor D.; Malcolm, David; McIntosh, Kevin D., Blood centrifuge with exterior mounted, self-balancing collection chambers.
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Brown Richard I. (Northbrook IL), Blood processing systems and methods which monitor citrate return to the donor.
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Hoeppner, Jacy C., Blood separating device.
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Westberg, Tom; Smith, Kelly B; Joie, Michel L. F., Blood separation chamber.
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Leach, Michael D.; Dorian, Randel; Hoeppner, Jacy C., Buoy fractionation system.
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Leach, Michael D.; Dorian, Randel; Hoeppner, Jacy C., Buoy fractionation system.
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Leach, Michael D.; Dorian, Randel; Hoeppner, Jacy C., Buoy suspension fractionation system.
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Leach, Michael D.; Dorian, Randel; Hoeppner, Jacy C., Buoy suspension fractionation system.
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Leach, Michael D.; Dorian, Randel; Hoeppner, Jacy C., Buoy suspension fractionation system.
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Leach, Michael D.; Dorian, Randel; Hoeppner, Jacy C., Buoy suspension fractionation system.
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Leach, Michael D.; Dorian, Randel; Storrs, Richard W.; King, Scott R., Cell washing plunger using centrifugal force.
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Brown, Richard I.; Smith, Sidney; Cerny, David E.; Foley, John T., Centrifugation pheresis method.
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Dolecek, Victor D.; Malcolm, David, Centrifuge container and methods of use.
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Dolecek, Victor D., Centrifuge container having curved linear shape.
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Dolecek, Victor D.; Berg, Gary L.; Merte, Kenneth E.; Malcolm, David; McIntosh, Kevin D.; Sitko, Vitaly G., Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma.
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Dolecek,Victor D.; Berg,Gary L.; Merte,Kenneth E.; Malcolm,David; McIntosh,Kevin D.; Sitko,Vitaly G., Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma.
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Dolecek,Victor D.; Berg,Gary L.; Merte,Kenneth E.; Malcolm,David; McIntosh,Kevin D.; Sitko,Vitaly G., Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma.
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Dolecek,Victor D.; Berg,Gary L.; Merte,Kenneth E.; Malcolm,David; McIntosh,Kevin D.; Sitko,Vitaly G., Centrifuge system utilizing disposable components and automated processing of blood to collect platelet rich plasma.
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Gordon Timothy M. ; Scovill Stephen K. ; Fletcher-Haynes Peter ; Martin Scott, Method and apparatus for occlusion monitoring using pressure waveform analysis.
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Dorian, Randel; Leach, Michael D., Method and apparatus for preparing platelet rich plasma and concentrates thereof.
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Dorian, Randel; Leach, Michael D., Method and apparatus for preparing platelet rich plasma and concentrates thereof.
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Dorian, Randel; Leach, Michael D., Method and apparatus for preparing platelet rich plasma and concentrates thereof.
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Swift, Matthew J; Hecker, Barry F; Leach, Michael D, Method and apparatus for producing autologous clotting components.
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Swift, Matthew; Hecker, Barry F.; Leach, Michael D., Method and apparatus for producing autologous clotting components.
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Swift, Matthew; Hecker, Barry F.; Leach, Michael D., Method and apparatus for producing autologous clotting components.
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Hecker, Barry F.; Leach, Michael D., Method and apparatus for producing autologous thrombin.
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Hecker, Barry F.; Leach, Michael D., Method and apparatus for producing autologous thrombin.
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Chavarria, Jason; Leach, Michael D., Method and apparatus for separating a material.
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Leach, Michael D.; Higgins, Joel C.; Swift, Matthew; Gordon, Nathan, Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles.
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Leach, Michael D.; Chavarria, Jason, Method and apparatus for separating biological materials.
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Briggs,Dennis A.; Hutchinson,Michael, Method and apparatus for the continuous separation of biological fluids into components.
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Brown Richard I. (Northbrook IL) Smith Sidney (Lake Forest IL) Cerny David E. (Crystal Lake IL) Foley John T. (Wheeling IL), Method for collecting a blood component concentration.
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Briggs, Dennis, Method for collecting a desired blood component and performing a photopheresis treatment.
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Briggs, Dennis, Method for collecting a desired blood component and performing a photopheresis treatment.
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Briggs,Dennis, Method for collecting a desired blood component and performing a photopheresis treatment.
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Dorian, Randel; Leach, Michael D., Method for preparing platelet rich plasma and concentrates thereof.
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Leach, Michael D.; Dorian, Randel; Hoeppner, Jacy C., Method of separating a selected component from a multiple component material.
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Robinson, Thomas C.; Robinson, Thomas P.; D'Elia, Richard; Sahines, Thomas; Eibe, Paul, Method of simultaneous blood collection and separation using a continuous flow centrifuge having a separation channel.
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Dorian, Randel; King, Scott R.; Storrs, Richard W., Methods and apparatus for isolating platelets from blood.
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Brown Richard I. ; Smith Sidney ; Cerny David E. ; Foley John T., Methods of accumulating separated blood components in a rotating chamber for collection.
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Brown Richard I. ; Smith Sidney ; Cerny David E. ; Foley John T., Methods of collecting a blood plasma constituent.
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Rosiello, Keith M., Processing bag for component separator system and method of removing separated components.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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