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Polyisobutylene adhesives for transdermal devices 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61L-015/00
출원번호 US-0509644 (1990-04-16)
발명자 / 주소
  • Wang Karly S. (Newark CA) Osborne James L. (Mountain View CA) Hunt James A. (Fremont CA) Nelson Melinda K. (Sunnyvale CA)
출원인 / 주소
  • Alza Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 40  인용 특허 : 26

초록

An in-line adhesive, useful for transdermal delivery devices comprising a mixture of high and low molecular weighted polyisobutylene having a ratio HMW PIB:LMW PIB in the range of about 5-40:95-60 which is substantially free of plasticizers and tackifiers is disclosed. The adhesive finds particular

대표청구항

A polyisobutylene (PIB) adhesive composition for use in a transdermal active agent delivery device, said adhesive composition comprising an oily, non-polar liquid active agent dissolved in a polymeric component consisting essentially of a mixture of high molecular weight (HMW) PIB having an average

이 특허에 인용된 특허 (26)

  1. Fix Joseph A. (Lawrence KS) Pogany Stefano A. (Lawrence KS), a 상세보기
  • von Bittera Miklos (Leverkusen DEX) Meyer Rolf-Volker (Krefeld DEX), Active compound release systems.
  • Alexander Jose (Lawrence KS) Fix Joseph A. (Lawrence KS), Adjuvants for rectal delivery of drug.
  • Rose Jed E. (Venice CA), Aerosol for use in the reduction of tobacco smoking.
  • Rosenberg Barnett (2410 College Rd. Holt MI 48842), Analgesic composition and method of relieving pain.
  • Kydonieus Agis (Kendall Park NJ) Shah Kishore R. (Bridgewater NJ) Berner Bret (Ardsley on Hudson NY), Article useful for administration of pharmacologically-active substances transdermally, orally, or by means of implant.
  • Urquhart John (Palo Alto CA) Chandrasekaran Santosh Kumar (Palo Alto CA) Shaw Jane Elizabeth (Atherton CA), Bandage for transdermally administering scopolamine to prevent nausea.
  • Higuchi Takeru (Lawrence KS) Hussain Anwar (Lexington KY), Device consisting of copolymer having acetoxy groups for delivering drugs.
  • Leeson Lewis J. (Roseland NJ), Devices and methods for treating memory impairment.
  • Campbell, Patricia S.; Chandrasekaran, Santosh K., Dosage for coadministering drug and percutaneous absorption enhancer.
  • von Bittera Miklos (Leverkusen DEX) Dhein Rolf (Krefeld DEX) Meyer Rolf-Volker (Krefeld DEX) Rupp Roland (Leichlingen DEX), Isobutylene polymer active compound release systems.
  • Urquhart John (Palo Alto CA) Chandrasekaran Kumar (Palo Alto CA) Shaw Jane (Atherton CA), Method and therapeutic system for administering scopolamine transdermally.
  • Chandrasekaran Santosh Kumar (Palo Alto CA) Urquhart John (Palo Alto CA) Shaw Jane Elizabeth (Atherton CA), Method and therapeutic system for providing chemotherapy transdermally.
  • Hutchinson Ronald R. (Augusta MI) Emley Grace S. (Augusta MI), Method for treating hypertension with nicotine.
  • Guse Gnter (Hamburg DEX) Asmussen Bodo (Ammerbek DEX) Bss Johannes (Hamburg DEX) Borchert Gnter (Hamburg DEX), Nitrate-containing plaster.
  • Baker Richard W. (Palo Alto CA) Kochinke Frank (Mt. View CA) Huang Carl (Palo Alto CA), Novel transdermal nicotine patch.
  • Rajadhyaksha, Vithal J., Penetration enhancers for transdermal drug delivery of systemic agents.
  • Boerzel Paul (Frankenthal DEX) Bronstert Klaus (Carlsberg DEX) Hovemann Friedrich (Hockenheim DEX), Polyisobutenes.
  • Hartog ; Jan ; Zwagemakers ; Johannes M. A., Spasmolytics.
  • Hartog Jan (Weesp NL) Zwagemakers Johannes Maria Antonius (Weesp NL), Spasmolytics.
  • Chandrasekaran Santosh K. (Palo Alto CA) Darda Siegfried (Ingelheim am Rhein CA DEX) Michaels Alan S. (Atherton CA) Cleary Gary W. (Palo Alto CA), Therapeutic system for administering clonidine transdermally.
  • Chandrasekaran Santosh K. (Palo Alto CA), Therapeutic system for administering drugs to the skin.
  • Etscorn Frank T. (121 Stallion Cir. Socorro NM 87801), Transcutaneous application of nicotine.
  • Loper Alice E. (Lederach PA) Majumdar Anup K. (Eatontown NJ), Transdermal drug delivery system.
  • Chen Yu-Ling (Cupertino CA) Chun Leslie L. (Palo Alto CA) Enscore David J. (Sunnyvale CA), Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine.
  • Roszkowski Adolph P. (Saratoga CA), Treatment of Alzheimer\s disease.
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    2. Akemi, Hitoshi; Ninomiya, Kazuhisa; Kuroda, Hidetoshi; Matsuoka, Kensuke; Saeki, Yuji; Nishimura, Masato, Adhesive material and adhesive preparation.
    3. Iwao, Yoshihiro; Ookubo, Katsuyuki; Okada, Katsuhiro; Minami, Kunihiro; Yuasa, Shuichiro, Adhesive pharmaceutical preparation containing bisoprolol.
    4. Saeki, Yuji; Nishimura, Masato; Matsuoka, Kensuke; Muraoka, Takateru; Hosaka, Yoshifumi; Hori, Mitsuhiko; Ninomiya, Kazuhisa; Akemi, Hitoshi; Kuroda, Hidetoshi, Adhesive preparation containing fentanyl.
    5. Karandikar, Bhalchandra M.; Gibbins, Bruce L., Antimicrobial amorphous compositions.
    6. Karandikar, Bhalchandra M.; Gibbins, Bruce L.; Cornell, Ken A., Antimicrobial devices and compositions.
    7. Karandikar, Bhalchandra M.; Gibbins, Bruce L.; Cornell, Ken A., Antimicrobial silver compositions.
    8. Karandikar, Bhalchandra M.; Gibbins, Bruce L.; Cornell, Kenneth A., Antimicrobial silver compositions.
    9. McMaken, Jack D.; Gibbins, Bruce L., Antimicrobial site dressings.
    10. Kimura Katsuhiko,JPX ; Aoyama Taizo,JPX, Composite rubber particles and graft copolymer particles of composite rubber.
    11. Gibbins, Bruce L.; Hopman, Lance D., Devices for delivering oxygen to the wounds.
    12. Enscore David J. ; Campbell Patricia S. ; Nedberge Diane ; Frame Richard D., Drug delivery devices and process of manufacture.
    13. Enscore David J. ; Campbell Patricia S. ; Nedberge Diane ; Frame Richard D., Drug delivery devices and process of manufacture.
    14. Nakamura Katsuhiro,JPX ; Koga Nobuyuki,JPX, Formulation for percutaneous administration for treating disturbance in micturition.
    15. Audett, Jay; Wen, Jianye; Goldman, Eli J.; Gale, Robert M.; Luciano, Allison; Foreman, Paul B.; Silverberg, Eric N., High enhancer-loading polyacrylate formulation for transdermal applications.
    16. Audett, Jay; Wen, Jianye; Goldman, Eli J.; Gale, Robert M.; Luciano, Allison; Foreman, Paul B.; Silverberg, Eric N., High enhancer-loading polyacrylate formulation for transdermal applications.
    17. Audett, Jay; Wen, Jianye; Goldman, Eli J.; Gale, Robert M.; Luciano, Allison; Foreman, Paul B.; Silverberg, Eric N., Method of making a high enhancer-loading polyacrylate formulation for transdermal applications.
    18. Karandikar, Bhalchandra M.; Gibbins, Bruce L., Methods and compositions for metal nanoparticle treated surfaces.
    19. Maley, Joseph C.; Gibbins, Bruce L., Methods and compositions for treatment of dermal conditions.
    20. Robert Martin Gale, Methods for transdermal drug administration.
    21. Gibbins, Bruce L.; Hopman, Lance D., Oxygen-delivery closed cell foam matrix for wound treatment.
    22. Nishimura, Masato; Iwao, Yoshihiro; Okada, Katsuhiro; Matsuoka, Kensuke, Patch and patch preparation.
    23. Nishimura, Masato; Iwao, Yoshihiro; Okada, Katsuhiro; Matsuoka, Kensuke, Patch and patch preparation.
    24. Iwao, Yoshihiro; Matsuoka, Kensuke; Okada, Katsuhiro; Minami, Kunihiro; Yuasa, Shuichiro, Percutaneous administration device of bisoprolol.
    25. Gibbins, Bruce L.; Hopman, Lance D., Silver-containing compositions, devices and methods for making.
    26. Radloff,Detlev; Wasner,Matthias, Skin friendly active substance patch for transdermal administration of hyperemic active substances.
    27. Aoyama Taizo,JPX ; Kimura Katsuhiko,JPX, Thermoplastic resin composition.
    28. Sivaraman, Arunprasad; Simmons, Tyler D.; Fieldson, Gregory T.; Sorensen, Adam C.; Cortopassi, Jeffrey E., Transdermal dosage form for low-melting point active agent.
    29. Sivaraman, Arunprasad; Simmons, Tyler D.; Fieldson, Gregory T.; Sorensen, Adam C.; Cortopassi, Jeffrey E., Transdermal dosage form for low-melting point active agent.
    30. Gale, Robert M.; Audett, Jay; Padmanabhan, Rama V.; Cormier, Michel J. N.; Luciano, Allison; Silverberg, Eric N.; Foreman, Paul B., Transdermal nicotine salt delivery system.
    31. Gale, Robert M.; Audett, Jay; Padmanabhan, Rama V.; Cormier, Michel J. N.; Luciano, Allison; Silverberg, Eric N.; Foreman, Paul B., Transdermal nicotine salt delivery system.
    32. Burton Scott Allison ; Tata Shahnaz, Transdermal patch.
    33. Jona Janan ; Audett Jay ; Singh Noel, Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen.
    34. Jona Janan ; Audett Jay ; Singh Noel, Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen.
    35. Woeller, Karl-Heinz; Kolbe, Ludger; Scherner, Cathrin; Wolber, Rainer, Transdermal therapeutic patches containing 4-N-butylresorcinol.
    36. Gale, Robert M., Transparent transdermal nicotine delivery devices.
    37. Gale, Robert M., Transparent transdermal nicotine delivery devices.
    38. Gale, Robert M., Transparent transdermal nicotine delivery devices.
    39. Gale, Robert M., Transparent transdermal nicotine delivery devices.
    40. Gale, Robert M., Transparent transdermal nicotine delivery devices.
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