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Viscous suspensions of controlled-release drug particles 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/70
출원번호 US-0307843 (1994-09-30)
국제출원번호 PCT/US93/02992 (1993-03-30)
§371/§102 date 19940930 (19940930)
국제공개번호 WO-9319739 (1993-10-14)
발명자 / 주소
  • Roorda Wouter E. (Newark CA) Ehnow Fred (Mountain View CA)
출원인 / 주소
  • Alza Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 123  인용 특허 : 0

초록

Controlled-release particles containing biologically effective agents such as therapeutic drugs and local anesthetics are suspended in a liquid suspending vehicle which has an elevated viscosity, the viscosity being substantially higher than that of water. Preferred vehicles are non-aqueous liquids

대표청구항

A controlled release bupivacaine composition for localized application comprising an even suspension of bupivacaine-containing bioerodible particles in a liquid vehicle, said composition comprising: a liquid suspending vehicle having a viscosity ranging from about 10 to about 2,000,000 centipoise at

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