초록 ▼

Lesions supplied by abnormal aggregations of vascular tissue or neovascular tissues are treated with photodynamic therapy by application of photosensitizing agent followed by precisely directed and calibrated laser activation to induce photothrombosis within target vascular tissue. The treatment for

Lesions supplied by abnormal aggregations of vascular tissue or neovascular tissues are treated with photodynamic therapy by application of photosensitizing agent followed by precisely directed and calibrated laser activation to induce photothrombosis within target vascular tissue. The treatment forms a blood clot within the supply vessels thereby reducing the blood supply to the target lesion. Treated tissues atrophy or recede with low regrowth of vessels. The lower energy levels required significantly reduce damage to the surrounding tissues.

대표청구항 ▼

A method of photodynamic therapy by a process comprising the steps of: locally applying a photosensitizing agent to target tissue consisting essentially of tissues containing blood-carrying vessels supplying an undesired lesion and avoiding adverse general light sensitivity found with intravenous ad

A method of photodynamic therapy by a process comprising the steps of: locally applying a photosensitizing agent to target tissue consisting essentially of tissues containing blood-carrying vessels supplying an undesired lesion and avoiding adverse general light sensitivity found with intravenous administration of sensitizing agents, the photosensitizing agent being in a pharmaceutically acceptable composition for contact with said target tissue; illuminating an area consisting essentially of the treated blood-carrying vessels with light from a laser emitting light of a frequency and energy level lower than that used for general tissue irradiation leading to tissue destruction or genetic changes but which excites the photosensitizing agent and coagulates blood in said vessels.