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Tocotrienols and tocotrienol-like compounds and methods for their use 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/355
  • C07D-311/22
  • C07D-311/72
출원번호 US-0244215 (1994-08-15)
국제출원번호 PCT/US92/10277 (1992-11-20)
§371/§102 date 19940815 (19940815)
국제공개번호 WO-9309777
발명자 / 주소
  • Lane Ronald H. (Phoenix AZ) Qureshi Asaf A. (Madison WI) Salser Winston A. (Pacific Palisades CA)
출원인 / 주소
  • Lipogenics, Inc. (Scottsdale AZ 02)
인용정보 피인용 횟수 : 64  인용 특허 : 9

초록 ▼

The present invention relates to novel tocotrienols and tocotrienol-like compounds displaying biological activity. The tocotrienols and tocotrienol-like compounds of this invention may be conveniently obtained from biological sources or by chemical synthesis and may be used in pharmaceutical composi

대표청구항 ▼

A tocotrienol comprising 3,4-dihydro-2-(4,8,12-trimethyltrideca-3′(E), 7′(E), 11′-trienyl)-2H-1-benzopyran-6-ol), and having the structure: [Figure] A tocotrienol comprising: [Figure] A composition comprising a tocotrienol compound resulting from a process comprising the steps of: stabilizing a biol

이 특허에 인용된 특허 (9)

  1. Wang, Jonas C. T., Compositions and method for stabilization of anthralin comprising the addition of an oil soluble antioxidant and an anionic surfactant.
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  2. Ohgaki Kazunari (Nara JPX) Katayama Takashi (Toyonaka JPX), Extractive separation method.
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  3. Pearce Bradley C. (East Hampton CT), Farnesylated tetrahydro-naphthalenols as hypolipidemic agents.
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  4. Pearce Bradley C. (East Hampton CT), Farnesylated tetrahydro-naphthalenols as hypolipidemic agents.
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  5. Schmidt Douglass N. (Grosse Ile MI), Free-flowing, high density, fat soluble vitamin powders with improved stability.
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  6. Marshall Lisa A. (Wayne PA) Steiner Kurt E. (Devon PA) Schiehser Guy A. (Malvern PA), Phospholipase A2 inhibitors.
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  7. Pearce Bradley C. (East Hampton CT), Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia.
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  8. Wright John J. (North Guilford CT) Pearce Bradley C. (East Hampton CT) Parker Rex (Branford CT) Qureshi Asaf A. (Madison WI), Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders.
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  9. Wright John J. (North Guilford CT) Pearce Bradley C. (East Hampton CT) Parker Rex (Branford CT) Qureshi Asaf A. (Madison WI), Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders.
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  64. Hyatt John A., Water-dispersible or water-soluble D-tocotrienol compounds and methods for making therefor.
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