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Pharmaceutical formulations of osteogenic proteins 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07K-014/51
출원번호 US-0081378 (1993-06-29)
국제출원번호 PCT/US92/05309 (1992-06-22)
§371/§102 date 19930629 (19930629)
국제공개번호 WO-9300050 (1993-01-07)
발명자 / 주소
  • Ron Eyal (Lexington MA) Turek Thomas J. (Boston MA) Isaacs Benjamin S. (Tewksbury MA) Patel Himakshi (Tewksbury MA) Kenley Richard A. (Andover MA)
출원인 / 주소
  • Genetics Institute, Inc. (Cambridge MA 02)
인용정보 피인용 횟수 : 124  인용 특허 : 12

초록

A composition comprising a pharmaceutically acceptable admixture of an osteogenic protein; a polymer matrix component selected from the group consisting of poly(lactic acid), poly(glycolic acid), and copolymers of lactic acid and glycolic acid; and an osteogenic protein-sequestering material.

대표청구항 ▼

A composition comprising a pharmaceutically acceptable admixture of (i) an ostcogenic protein; (ii) a polymer matrix component selected from the group consisting of poly(lactic acid), poly(glycolic acid), and copolymers of lactic acid and glycolic acid; and (iii) an osteogenic protein-sequestering a

이 특허에 인용된 특허 (12)

  1. Urist Marshall R. (Pacific Palisades CA), Biodegradable organic polymer delivery system for bone morphogenetic protein.
    상세보기
  2. Kuberasampath Thangavel (Medway MA) Ridge Richard J. (Acton MA), Bone collagen matrix for zenogenic implants.
    상세보기
  3. Schmitt Edward Emil (Palo Alto CA) Polistina Rocco Albert (Port Chester NY), Controlled release of medicaments using polymers from glycolic acid.
    상세보기
  4. Yamamoto Masaki (Osaka JPX) Takada Shigeyuki (Suita JPX) Ogawa Yasuaki (Ibaraki ; all JPX), Method for producing microcapsule.
    상세보기
  5. Kuberasampath Thangavel (Medway MA) Rueger David C. (West Roxbury MA), Osteogenic devices.
    상세보기
  6. Wang Elizabeth A. (Carlisle MA) Wozney John M. (Hudson MA) Rosen Vicki (Boston MA), Osteoinductive factors.
    상세보기
  7. Higashi Kiyotsugu (Nara JPX) Kametaka Shigeru (Osaka JPX) Izumi Reiko (Osaka JPX) Morisaki Katsuhiko (Nara JPX) Hayashi Shin\ichi (Osaka JPX), Pharmaceutical composition for treating periodontal.
    상세보기
  8. Schmitz John P. (Columbia MD), Polyactic-polyglycolic acid copolymer combined with decalcified freeze-dried bone for use as a bone repair material.
    상세보기
  9. Nieuwenhuis Jan (Gorinchem NLX) Mol Arie C. (Papendrecht NLX), Polymer lactide, method for preparing it and a composition containing it.
    상세보기
  10. Augurt Thomas Anthony (Stamford CT) Rosensaft Michael Norman (Monsey NY) Perciaccante Vincent Anthony (Long Island NY), Polymers of unsymmetrically substituted 1,4-dioxane-2,5-diones.
    상세보기
  11. DeLuca Patrick P. (Lexington KY) Kanke Motoko (Fukuyama JPX) Sato Toyomi (Tokyo CA JPX) Schroeder Hans G. (Encinitas CA), Porous microspheres for drug delivery and methods for making same.
    상세보기
  12. Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Osaka JPX) Yashiki Takatsuka (Hyogo JPX), Prolonged release microcapsules.
    상세보기

이 특허를 인용한 특허 (124)

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