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Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprisi 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-001/02
  • C12N-005/00
출원번호 US-0372782 (1995-01-13)
발명자 / 주소
  • Brasile Lauren (Albany NY) Clarke Jolene (Ballston Spa NY)
출원인 / 주소
  • Breonics, Inc. (Schenectady NY 02)
인용정보 피인용 횟수 : 76  인용 특허 : 1

초록 ▼

The present invention is directed to a new hyperosmolar preservation solution useful in supporting the simultaneous in vitro growth of, and preservation of vascular endothelial cells from large vessel and microvessel origins. In addition, the preservation solution of the present invention may be use

대표청구항 ▼

A solution with an osmolarity of 330 to 600 mOsm comprising: (a) a cell culture medium; (b) Mg++in a concentration greater than 10mmol/L; and (c) chondroitin sulfate, heparin, cyclodextrin, insulin, cholesterol, pyruvate, and retinal-derived fibroblast growth factor in concentrations sufficient to p

이 특허에 인용된 특허 (1)

  1. Bellamy Robert W. (Zama JPX) Horikoshi Kouki (Tokyo JPX), Process for producing heparinase with a bacilius strain.
    상세보기

이 특허를 인용한 특허 (76)

  1. Ritchie, Greg; Lambert, II, Vincent; Bringham, Richard; Sullivan, John; Hassanein, Waleed H., Aortic cannula for ex vivo organ care system.
    상세보기
  2. Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  3. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  4. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  5. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  6. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis J.; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  7. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis J.; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  8. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  9. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Schein, Douglas; Harris, Stanley; Steibel, Dennis; Fraser, Richard; Isaacs, Dickon, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  10. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Schein, Douglas; Isaacs, Dickon, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
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  24. Wright, David Walter; Garland, Jeffrey C., Device for separating gas from a liquid path.
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  29. Schein, Douglas; Travis, Lee William, Method and apparatus for holding a plurality of tubes connectible to an organ or tissue container.
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  30. Garland, Jeffrey C.; Schein, Douglas; Wright, David Walter, Method and apparatus for transferring heat to or from an organ or tissue container.
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