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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0483331 (1995-06-07) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 428 인용 특허 : 0 |
A system and method for accomplishing a plurality of combinatorial processes in parallel comprising a microelectronic and fluidic array (device array) having micron-sized reservoirs, connecting microchannels and reaction cells etched into a substrate. The device array is supported by a station which
A system and method for accomplishing a plurality of combinatorial processes in parallel comprising a microelectronic and fluidic array (device array) having micron-sized reservoirs, connecting microchannels and reaction cells etched into a substrate. The device array is supported by a station which serves to interface and perform electro-optic measurements of material in the reaction cells of the device array. The device array incorporates a modular configuration with three distinct layers or plates. The device array comprises a top feedthru plate, a center distribution plate and a bottom cell plate. The three plates are stacked vertically and coupled together to form a liquid-tight seal. Reservoirs, microchannels and reactions cells are controllably etched onto the plates using traditional semiconductor fabrication techniques. The top feedthru plate serves as a cover for the device array and contains apertures selectively positioned above the reservoirs located in the center distribution plate. The center distribution plate comprises a plurality of micron sized reservoirs, microchannels, reservoir feeds, cell feeds and overflow feeds for the distribution of reagent fluids to the reaction cells located in the bottom cell plate. The detachable bottom cell plate serves as a microlaboratory tray of reaction cells. Once the proper reagents or other materials are introduced into the reaction cells, the bottom cell plate is decoupled from the device array and removed for incubation or analysis.
An array for accomplishing various chemical processes through the use of fluids, the array comprising: a plurality of reservoirs, microchannels and reaction cells disposed on a dielectric substrate, where fluids are selectively channeled from the plurality of reservoirs to the plurality of reaction
An array for accomplishing various chemical processes through the use of fluids, the array comprising: a plurality of reservoirs, microchannels and reaction cells disposed on a dielectric substrate, where fluids are selectively channeled from the plurality of reservoirs to the plurality of reaction cells through the plurality of microchannels; a plurality of micropumps located in the array for pumping fluid through the microchannels; and a plurality of dams located in the array, each for inhibiting the flow of fluid in one of the microchannels.
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