초록 ▼

There is disclosed a system and assemblage for producing microtexturized surfaces on implants for use in vertebrate animals, including humans and on substrates for use in growing and developing tissues and/or cells in vitro. By using the disclosed system and assemblage, the geometric configuration a

There is disclosed a system and assemblage for producing microtexturized surfaces on implants for use in vertebrate animals, including humans and on substrates for use in growing and developing tissues and/or cells in vitro. By using the disclosed system and assemblage, the geometric configuration and the dimensions of the microtexturized surfaces can be pre-determined to impart a customized design texture on the implant or substrate surface thereby optimizing implant acceptance by and durability in the host tissue and the in vitro promotion of the growth and development of various types of cell tissue on substrates.

대표청구항 ▼

An assemblage for producing pre-determined, microgeometric, texturized designs on the surface of implants and substrates comprising: (a) an excimer laser for producing an optical laser beam; (b) at least a first optical mirror positioned to direct said optical laser beam to an attenuator capable of

An assemblage for producing pre-determined, microgeometric, texturized designs on the surface of implants and substrates comprising: (a) an excimer laser for producing an optical laser beam; (b) at least a first optical mirror positioned to direct said optical laser beam to an attenuator capable of controlling the excitation voltage of said excimer laser and an homogenizer capable of maximizing the usable fraction of said optical laser beam and forming said optical laser beam to have a pre-determined, geometric cross section configuration; (c) at least a second optical mirror positioned to direct said optical laser beam from said attenuator to a design image selection means which is a member selected from (i) an optical prism having at least one refractive surface and at least one reflective surface; or, (ii) a pair of opposed, concave optical mirrors arranged with their concave surfaces facing each other, one of said mirrors having a port formed therein to receive said optical laser beam and the other of said mirrors having a plurality of ports formed therein to permit the refracted and reflected optical laser beam to pass therethrough, such that said design image selection means defines pre-selected line and space combinations; (d) at least a third optical mirror positioned to direct said optical laser beam from said design image selection means to a surface of said implant or substrate; and, (f) an aperture and aperture illuminator which, in combination, are capable of projecting a pre-selected segment of an image of said optical laser beam exiting from said design image selection means onto the surface of said implant or substrate.