$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Phosphinic ester substituted benzopyran derivatives 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/665
  • C07F-009/28
출원번호 US-0479324 (1995-06-07)
발명자 / 주소
  • Misra Raj N. (Hopewell NJ)
출원인 / 주소
  • Bristol-Myers Squibb Company (Princeton NJ 02)
인용정보 피인용 횟수 : 0  인용 특허 : 53

초록

[Figure] I and pharmaceutically acceptable salts thereof wherein Y is a single bond, －CH2－, －C(O)－, －S－or －N(R11)－; and R1 to R6 are as defined herein. These compounds have potassium channel activating activity and are useful, therefore for example, as cardiovascular agents.

대표청구항

A compound of the formula [Figure] I where R1 is [Figure] R2 is hydroxy; R3 and R4 are each independently hydrogen or alkyl; R5 is alkyl; R6 is aryl; R7 is aryl or heterocyclo; R8 is hydrogen; R9 is hydrogen; Y is －O－; and Z is NCN or O.

이 특허에 인용된 특허 (53)

  1. Cassidy Frederick (Harlow GB2) Stemp Geoffrey (Harlow GB2) Evans John M. (Harlow GB2), 3,4-dihydro-2H-1-benzopyrans useful as anti-hypertensive agents.
    상세보기
  2. Evans John M. (Roydon GB2), 4-Haloalkylamino substituted chromanol useful as antihypertensive agent.
    상세보기
  3. Atwal Karnail S. (Newtown PA), 4-substituted benzopyran and related compounds.
    상세보기
  4. Evans John M. (Harlow GB2) Stemp Geoffrey (Harlow GB2) Cassidy Frederick (Harlow GB2), Active compounds.
    상세보기
  5. Evans John M. (Roydon GB2) Stemp Geoffrey (Harlow GB2) Cassidy Frederick (Harlow GB2), Active compounds.
    상세보기
  6. Stemp Geoffrey (Harlow GB2) Evans John M. (Harlow GB2) Burrell Gordon (Swarthmoor ; Nr. Ulverston GB2), Amino pyrimidin-7-yl substituted benzopyrans for treatment of hypertension.
    상세보기
  7. Evans John M. (Roydon GB2) Cassidy Frederick (Harlow GB2), Anti-hypertensive chromanol derivatives.
    상세보기
  8. Evans John M. (Roydon GB2) Showell Graham A. (Harlow GB2) Fake Charles S. (Harlow GB2), Anti-hypertensive chromanol derivatives.
    상세보기
  9. Evans John M. (Roydon GB2) Showell Graham A. (Harlow GB2) Fake Charles S. (Harlow GB2), Anti-hypertensive chromanol derivatives.
    상세보기
  10. Evans John M. (Roydon GB2) Cassidy Frederick (Harlow GB2), Anti-hypertensive chromans and chromenes.
    상세보기
  11. Hammond Milton L. (Somerville NJ) Zambias Robert A. (Springfield NJ), Anti-inflammatory substituted 2-benzyl-mercapto-imidazole and pyrimidine derivatives compositions and method of use ther.
    상세보기
  12. Atwal Karnail (Newtown PA), Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers.
    상세보기
  13. Atwal Karnail (Newtown PA) McCullough John R. (Newtown PA) Grover Gary J. (Stockton NJ), Aryl cyanoguanidines: potassium channel activators and method of making same.
    상세보기
  14. Atwal Karnail S. (Newtown PA) Rovnyak George C. (Hopewell NJ), Aryl urea (thiourea) and cyanoguanidine derivatives.
    상세보기
  15. Yamanaka Tsutomu (Nakatsu JPX) Seki Toshio (Nakatsu JPX) Nakajima Tohru (Nakatsu JPX) Yaoka Osamu (Nakatsu JPX), Benzopyran compound and its pharmaceutical use.
    상세보기
  16. Yamanaka Tsutomu (Nakatsu JPX) Seki Toshio (Nakatsu JPX) Nakajima Tohru (Nakatsu JPX) Yaoka Osamu (Nakatsu JPX), Benzopyran compound and its pharmaceutical use.
    상세보기
  17. Yamanaka Tsutomu (Nakatsu JPX) Seki Toshio (Nakatsu JPX) Nakajima Tohru (Nakatsu JPX) Yaoka Osamu (Nakatsu JPX), Benzopyran compound and its pharmaceutical use.
    상세보기
  18. Ohtuka Katuyuki (Nagareyama JPX) Ishiyama Nobuo (Kusatsu JPX) Iida Yasuhito (Otsu JPX) Seri Kenji (Yashio JPX) Murai Takeshi (Fujimi JPX) Sanai Kazuko (Wako JPX) Ishizaka Yoshihiro (Tokyo JPX), Benzopyran compounds, processes for their production and pharmaceutical compositions.
    상세보기
  19. Attwood Michael R. (Hitchin GB2) Jones Philip S. (Stevenage GB2) Redshaw Sally (Stevenage GB2), Benzopyran derivatives.
    상세보기
  20. Atwal Karnail (Newtown PA), Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents.
    상세보기
  21. Shiokawa Youichi (Ibaraki JPX) Takimoto Koichi (Takarazuka JPX) Takenaka Kohei (Sakai JPX) Kato Takeshi (Ikeda JPX), Benzopyran derivatives and processes for preparation thereof.
    상세보기
  22. Shiokawa Youichi (Ibaraki JPX) Takimoto Koichi (Takarazuka JPX) Takenaka Kohei (Sakai JPX) Kato Takeshi (Ikeda JPX), Benzopyran derivatives and their use as anti-hypertensives.
    상세보기
  23. Evans John M. (Harlow GB2) Stemp Geoffrey (Harlow GB2) Cassidy Frederick (Harlow GB2), Benzopyran intermediates.
    상세보기
  24. Evans John M. (Roydon GB2), Benzopyrans useful for treating hypertension.
    상세보기
  25. Harada Hiroshi (Toyonaka JPX) Ohsugi Eiichi (Kawanishi JPX) Yonetani Yukio (Nara JPX) Shinosaki Toshihiro (Osaka JPX), Certain 3,4-dihydro 4-oxospiro [2H-1 benzopyrans]useful for treating hyperuricemia.
    상세보기
  26. Gericke Rolf (Seeheim DEX) Baumgarth Manfred (Darmstadt DEX) Lues Ingeborg (Darmstadt DEX) Bergmann Rolf (Reichelsheim DEX) De Peyer Jacques (Pfungstadt DEX), Chroman derivatives.
    상세보기
  27. Evans John M. (Roydon GB2), Chromanol derivatives.
    상세보기
  28. Atwal Karnail (Newtown PA) Rovnyak George C. (Hopewell NJ), Chromanyl substituted indole potassium channel openers.
    상세보기
  29. Kabbe Hans-Joachim (Leverkusen DEX) Widdig Arno (Odenthal DEX) Stendel Wilhelm (Wuppertal DEX) Roessler Peter (Bergisch Gladbach DEX), Combating arthropods with 2- and 4-substituted-chromanes.
    상세보기
  30. Hedrich Loren W. (Overland Park KS) Neighbors Ralph P. (Olathe KS), Control of unwanted vegetation with N-carbamylindolines.
    상세보기
  31. Evans John M. (Royden GB2), Cyanobenzano[b]pyrans.
    상세보기
  32. Stemp Geoffrey (Harlow GB2) Burrell Gordon (Harlow GB2) Smith David G. (Epsom GB2), Guanidino-substituted benzopyrans and their use as pharmaceuticals.
    상세보기
  33. Berge John M. (Epsom GB2) Cawthorne Michael A. (Epsom GB2), Heterocyclic compounds useful as a2-adrenoceptor antagonists.
    상세보기
  34. Evans John M. (Roydon GB2), Hypotensive 3,4-dihydro-2,2-dimethyl-4-amino-2H-benzo[b]pyran-3-ols.
    상세보기
  35. Atwal Karnail (Newtown PA), Indane and quinoline derivatives.
    상세보기
  36. Evans John M. (Roydon GB2), Method for treating congestive heart failure, angina, occlusive peripheral vascular disease or cerebral vascular disease.
    상세보기
  37. Atwal Karnail (Newtown PA) Grover Gary J. (Stockton NJ), Method of treating or prevention of fibrillation of the heart.
    상세보기
  38. Cozzi Paolo (Milan ITX) Carganico Germano (Milan ITX) Pillan Antonio (Milan ITX) Branzoli Umberto (Pavia ITX), N-imidazolyl derivatives of bicyclic compounds.
    상세보기
  39. Quagliato Dominick A. (North Brunswick NJ) Humber Leslie G. (North Brunswick NJ), Novel antihypertensive benzopyran derivatives.
    상세보기
  40. Stenzel Wolfgang (Reinbek DEX) Schotten Theo (Hamburg DEX) Armah Ben (Hamburg DEX), Novel benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds.
    상세보기
  41. Stenzel Wolfgang (Reinbek DEX) Schotten Theo (Hamburg DEX) Armah Ben (Hamburg DEX), Novel benzopyran derivatives, processes for their preparation and their use and preparations containing the compounds.
    상세보기
  42. Garcia Georges (Saint-Gely-du-Fesc FRX) Malta Alain D. (Saint-Gely-du-Fesc FRX) Soubrie Philippe (St. Mathieu de Treviers FRX), Novel chroman derivatives active on the central nervous system, their method of preparation and pharmaceutical compositi.
    상세보기
  43. Gericke Rolf (Seeheim DEX) Baumgarth Manfred (Darmstadt DEX) Lues Ingeborg (Darmstadt DEX) Bergmann Rolf (Reichelsheim DEX) De Peyer Jacques (Bern DEX), Oxodihydropyridyl chroman derivatives.
    상세보기
  44. Inazu Mizuho (Saitama JPX) Satoh Ryoichi (Saitama JPX) Inoue Tsutomu (Saitama JPX) Kitagawa Hiroshi (Kawajima JPX) Katoh Masakazu (Saitama JPX) Englert Heinrich (Hofheim am Taunus DEX) Carniato Denis, Pharmaceutical composition of benzopyranes for the inhibition of bone resorption.
    상세보기
  45. Blarer Stefan (Basel CHX) Morley John (Muttenz CHX) Chapman Ian D. (Basel CHX), Pharmaceutically useful benzo(b 상세보기
  • Timr Tibor (Tiszavasvri HUX) Eszenyi Tibor (Tiszavasvri HUX) Sebk Pter (Tiszavasvri HUX) Galamb Vilmos (Tiszavasvri HUX) Fazekas ne Kozk Julia (Tiszavasvri HUX) Istvn ne Katona Terzia (Tiszavasvri HU, Process for the preparation of anti-hypertensive benzopyran derivative.
    상세보기
  • Atwal Karnail (Newtown PA) Grover Gary J. (Stockton NJ) Kim Kyoung S. (Lawrenceville NJ), Pyranyl cyanoguanidine derivatives.
    상세보기
  • Gericke Rolf (Seeheim DEX) Baumgarth Manfred (Darmstadt DEX) Lues Ingeborg (Darmstadt DEX) Harting Jrgen (Darmstadt DEX) Bergmann Rolf (Reichelsheim DEX), Pyridaziny or oxodihydropyridazinyl chroman derivatives.
    상세보기
  • Cassidy Frederick (Harlow GB2) Faruk Erol A. (Harlow GB2), Pyrrolidinyl benzopyrans as hypotensive agents.
    상세보기
  • Schaus John M. (Zionsville IN) Hoechstetter Craig S. (Indianapolis IN) Huser Diane (Indianapolis IN) Paget Charles J. (Indianapolis IN) Titus Robert D. (Indianapolis IN), Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes and pharmaceutical compositions thereof.
    상세보기
  • Kabbe Hans-Joachim (Leverkusen DEX) Niewhner Ulrich (Wermelskirchen DEX) Widdig Arno (Odenthal DEX) Knorr Andreas (Wuppertal DEX) Garthoff Bernward (Hilden DEX) Kazda Stanislav (Wuppertal DEX), Substituted aminomethyl benzopyrans having anti-hypertensive activities.
    상세보기
  • Atwal Karnail (Newtown PA), Substituted cyanoimino benzopyranes.
    상세보기
  • Spicer Larry Dean (Princeton NJ) Pensack Joseph Michael (Trenton NJ) Wilbur Robert Daniel (Titusville NJ) Demkovich ; deceased Gary Michael (LATE OF Cranbury NJ BY Ruth Ellen Demkovich ; executrix), Ureidotetralin compounds.
    상세보기

    • 관련 콘텐츠

    문의처: helpdesk@kisti.re.kr전화: 080-969-4114

    Copyright KISTI. All Rights Reserved.

    AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

    AI-Helper 아이콘
    AI-Helper
    안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
    ※ AI-Helper는 부적절한 답변을 할 수 있습니다.

    선택된 텍스트

    맨위로