초록 ▼

An electrically powered transdermal iontophoretic delivery device (10, 20) and a method of making same is provided. The device utilizes electrode assemblies (8, 9 ) composed of a substantially homogenous blend of a polymeric matrix containing about 5 to 50 vol % of a conductive filler which forms a

An electrically powered transdermal iontophoretic delivery device (10, 20) and a method of making same is provided. The device utilizes electrode assemblies (8, 9 ) composed of a substantially homogenous blend of a polymeric matrix containing about 5 to 50 vol % of a conductive filler which forms a conductive network through the matrix, and up to about 50 vol % of the agent to be iontophoretically delivered through the skin. In the case of the donor electrode assembly, the agent is typically a drug and preferably a water soluble drug salt. In the case of the counter electrode assembly, the agent is typically an electrolyte salt. The homogenous blend eliminates the need for separate electrode and agent containing layers which require lamination.

대표청구항 ▼

An electrically powered iontophoretic delivery device including a donor electrode assembly adapted to be placed in agent transmitting relation with a body surface, a counter electrode assembly adapted to be placed in agent transmitting relation with a body surface and a source of electrical power ad

An electrically powered iontophoretic delivery device including a donor electrode assembly adapted to be placed in agent transmitting relation with a body surface, a counter electrode assembly adapted to be placed in agent transmitting relation with a body surface and a source of electrical power adapted to be electrically connected to the donor electrode assembly and the counter electrode assembly, wherein the donor electrode assembly comprises a polymeric matrix having a predetermined thickness, said matrix having homogeneously blended therein: about 5 to 50 vol % of a conductive filler forming a conductive network through the entire thickness of the matrix; and about 1 to 50 vol % of a therapeutic agent to be iontophoretically delivered through the body surface in order to obtain a therapeutic effect.