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Injectable drug delivery system and method 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-006/00
출원번호 US-0437471 (1995-05-09)
발명자 / 주소
  • Berggren Randall G. (Livermore CA) Enscore David J. (Saratoga CA) Marks Susan M. (San Jose CA) Osborne James L. (Mountain View CA) Wong Patrick S.-L. (Palo Alto CA) Roorda Wouter E. (Newark CA)
출원인 / 주소
  • ALZA Corporation (Palo Alto CA 02)
인용정보 피인용 횟수 : 68  인용 특허 : 28

초록 ▼

The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then del

대표청구항 ▼

A method for delivering a drug into a periodontal pocket, the method comprising: a) heating a drug-containing oligomeric or polymeric matrix material which is a less- to non-flowable polymer at or below body temperature and a flowable polymer at a physiologically compatible elevated temperature to i

이 특허에 인용된 특허 (28)

  1. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods for producing the same.
    상세보기
  2. Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  3. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  4. Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David P. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
    상세보기
  5. Dunn Richard L. (Fort Collins CO) Tipton Arthur J. (Fort Collins CO) Southard George L. (Fort Collins CO) Rogers Jack A. (Fort Collins CO), Biodegradable system for regenerating the periodontium.
    상세보기
  6. Loesche Walter J. (1814 Hermitage Ann Arbor MI 48104), Composition for periodontal administration.
    상세보기
  7. Capozza Richard C. (Palo Alto CA), Compositions comprising arylene substituted poly(orthoesters) containing useful agents.
    상세보기
  8. Baker Richard W. (Menlo Park CA), Controlled release drug delivery system for the periodontal pocket.
    상세보기
  9. Schmitt Edward E. (Palo Alto CA), Drug delivery devices comprising erodible polymer and erosion rate modifier.
    상세보기
  10. Choi ; Nam Sok ; Heller ; Jorge, Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates).
    상세보기
  11. Bucalo Louis (155 Roberts St. Holbrook NY 11741), Dynamic implants and method for implanting the same.
    상세보기
  12. Choi Nam S. (Seoul CA KRX) Heller Jorge (Palo Alto CA), Erodible agent releasing device comprising poly(orthoesters) and poly(orthocarbonates).
    상세보기
  13. Capozza Richard C. (Paradise Valley AZ), Erodible device comprising surfactant for modifying the rate of erosion of the device.
    상세보기
  14. Capozza Richard C. (Palo Alto CA), Fertilizer coated with orthoester polymer.
    상세보기
  15. Goodson Jo M. (Cambridge MA), Hollow-fiber devices for and a method of the treament and diagnosis of oral diseases.
    상세보기
  16. Bucalo Louis (155 Roberts St. Holbrook NY 11741), Implants for acting on living beings.
    상세보기
  17. Goodson J. Max (Cambridge MA), Intra-pocket drug delivery devices for treatment of periodontal diseases.
    상세보기
  18. Bucalo Louis (155 Roberts St. Holbrook NY 11741), Method and apparatus for providing living beings with absorbable implants.
    상세보기
  19. Lading Pia (Gentofte DKX) Lundsholm Yvonne (Oxie SEX) Norling Tomas (Copenhagen DKX), Method and composition for controlled delivery of biologically active agents.
    상세보기
  20. Choi Nam S. (Seoul CA KRX) Heller Jorge (Palo Alto CA), Novel orthoester polymers and orthocarbonate polymers.
    상세보기
  21. Schmitt Edward E. (Palo Alto CA), Pharmaceutical composition of poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having.
    상세보기
  22. Schmitt ; Edward Emil, Poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having carbonyloxy functionality.
    상세보기
  23. Capozza ; Richard Carl, Polymeric orthoesters.
    상세보기
  24. Capozza Richard C. (Palo Alto CA), Polymeric orthoesters having arylene arrangement.
    상세보기
  25. Capozza ; Richard C., Polymeric orthoesters housing beneficial drug for controlled release therefrom.
    상세보기
  26. Wahlig Helmut (Darmstadt DEX) Dingeldein Elvira (Dreieich DEX) Rothe Johannes (Rossdorf DEX) Stille Wolfgang (Frankfurt DEX), Process for implanting a medicament depot.
    상세보기
  27. Choi ; Nam S. ; Heller ; Jorge, Structured orthoester and orthocarbonate drug delivery devices.
    상세보기
  28. Damani Nalinkant C. (Cincinnati OH), Sustained release compositions for treating periodontal disease.
    상세보기

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  1. Gutierro Aduriz, Ibon; Gomez Ochoa, Maria Teresa, Antipsychotic injectable depot composition.
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  2. Gutierro Aduriz, Ibon; Gomez Ochoa, Maria Teresa, Antipsychotic injectable depot composition.
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  3. Hahn,Rainer; Irion,Klaus, Apparatus for applying material for selectively modifying the optical properties of metabolically different cells.
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  4. Dacquay, Bruno; Lind, Casey; Dos Santos, Cesario; Hallen, Paul R., Battery operated surgical hand piece with disposable end.
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  5. Dang, Wenbin; Kadiyala, Irina; Zhao, Zhong; English, James P.; Mao, Hai-quan; Leong, Kam W., Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same.
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  6. Wenbin Dang ; Hai-quan Mao ; Irina Kadiyala ; Kam W. Leong ; Zhong Zhao ; James P. English, Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same.
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  7. Kaplan, Edward J., Brachytherapy seed.
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  8. Chen, Guohua; Houston, Paul R.; Kleiner, Lothar; Spaltro, John, Catheter injectable depot compositions and uses thereof.
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  9. Shimizu, Yasumitsu, Composition for forming solid particles.
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  10. Chen,Guohua; Houston,Paul; Bannister,Roy; Kameda,Teresa; Priebe,David; Kleiner,Lothar, Controlled release depot formulations.
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  11. Wong, Vernon G.; Wood, Louis L., Conveniently implantable sustained release drug compositions.
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  12. Nicholson, William S. C.; Narang, Upvan; Stewart, Ubonwan A.; Hedgpeth, Daniel L.; Badejo, Ibraheem T.; Mainwaring, Lawrence H., Cyanoacrylate solutions containing preservatives.
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  13. Pauser, Helmut; Hampe, Rüdiger; Schulte, Christoph; Knee, Michael; Maurer, Andreas, Device and a method for delivery of a dental composition.
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  14. Pauser, Helmut; Hampe, Rüdiger; Schulte, Christoph; Knee, Michael; Maurer, Andreas, Device and a method for delivery of a dental composition.
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  15. Lamoureux, Gary A.; Matons, James; Johnston, Warren; Bouffard, Matthew; Rice, Warren, Devices to resist migration and rotation of implants used in brachytherapy and other radiation therapy.
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  16. Dacquay, Bruno; Dos Santos, Cesario; Foster, James; Sanchez, Robert, Disposable ophthalmic injection device.
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  17. Santos, Cesario Dos; Pinedjian, Raffi; Sanchez, Robert; Dacquay, Bruno; Lind, Casey, Drug casting.
    상세보기
  18. Sanchez, Robert; Foster, James; Dos Santos, Cesario, Dual thermal coefficient dispensing chamber.
    상세보기
  19. Pinedjian, Raffi, Easy cleaning C-shaped charging base.
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  20. Kaplan, Edward J., Flexible and/or elastic brachytherapy seed or strand.
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  21. Kaplan, Edward J., Flexible and/or elastic brachytherapy seed or strand.
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  22. Kaplan, Edward J., Flexible and/or elastic brachytherapy seed or strand.
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  23. Kaplan, Edward J., Flexible and/or elastic brachytherapy seed or strand.
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  24. Kaplan, Edward J., Flexible and/or elastic brachytherapy seed or strand.
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  25. Brodbeck Kevin J. ; Gaynor-Duarte Ann T. ; Shen Theodore Tao-Ian, Gel composition and methods.
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  26. Brodbeck, Kevin J.; Gaynor-Duarte, Ann T.; Shen, Theodore Tao-Ian, Gel composition and methods.
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  27. Kevin J. Brodbeck ; Ann T. Gaynor-Duarte ; Theodore Tao-Ian Shen, Gel composition and methods.
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  28. Canelli, Hugh B.; Chandrakant, Partha; Chon, James Y.; Sorensen, Gary P.; Wilson, Daniel J.; Gordon, Raphael, Hydraulic injector and methods for intra-ocular lens insertion.
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  29. Lamoureux, Gary A.; Matons, James; Johnston, Warren W.; Bouffard, Matthew; Rice, Warren, Implants including spacers for use in brachytherapy and other radiation therapy that resist migration and rotation.
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  30. Chen, Guohua; Houston, Paul R.; Kleiner, Lothar Walter; Spaltro, John J., Injectable depot compositions and uses thereof.
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  31. Brodbeck Kevin J. ; Shen Theodore T., Injectable depot gel composition and method of preparing the composition.
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  32. Berggren Randall G. ; Enscore David J. ; Marks Susan M. ; Osborne James L. ; Wong Patrick S.-L. ; Roorda Wouter E., Injectable drug delivery system and method.
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  33. Chen, Guohua; Houston, Paul; Kleiner, Lothar; Wright, Jeremy, Injectable multimodal polymer depot compositions and uses thereof.
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  34. Slepian Marvin J. ; Massia Stephen P., Local polymeric gel cellular therapy.
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  35. Dunn, Richard L., Low viscosity liquid polymeric delivery system.
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  36. Hahn, Rainer; Irion, Klaus, Material for differently modifying the optical properties of different cells.
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  37. Yukiko Asou JP; Hosei Shinoda JP; Hiroaki Tamatani JP, Medical composition of hydroxy acid-based oligomer.
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  38. Palasis, Maria, Method and apparatus for diagnostic and therapeutic agent delivery.
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  39. Palasis, Maria, Method and apparatus for diagnostic and therapeutic agent delivery.
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  40. Pinedjian, Raffi S., Method and apparatus for drug delivery.
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  41. Lennox Charles D., Method and device for delivery of therapeutic agents in conjunction with isotope seed placement.
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  42. Kaplan, Edward J., Method of administering a therapeutically active substance.
    상세보기
  43. Gutierro Aduriz, Ibon; Gomez Ochoa, Maria Teresa, Methods for the preparation of injectable depot compositions.
    상세보기
  44. Gutierro Aduriz, Ibon; Gomez Ochoa, Maria Teresa, Methods for the preparation of injectable depot compositions.
    상세보기
  45. Dos Santos, Cesario Pereira, Multi-layer heat assembly for a drug delivery device.
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  46. Dos Santos, Cesario Pereira; Gelvin, Michael LeRoy, Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device.
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  47. Dacquay, Bruno; Lind, Casey; Dos Santos, Cesario; Sanchez, Jr., Robert J, Ophthalmic injection device including dosage control device.
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  48. Dacquay, Bruno; Lind, Casey; Martin, Mike, Ophthalmic injection device using piezoelectric array.
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  49. Dacquay, Bruno; Lind, Casey; Martin, Mike, Ophthalmic injection device using shape memory alloy.
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  50. Dacquay, Bruno; Dos Santos, Cesario; Foster, James; Sanchez, Robert, Ophthalmic injection method.
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  51. Dacquay, Bruno; Dos Santos, Cesario; Foster, James; Lind, Casey; Pinedjian, Raffi; Sanchez, Robert, Ophthalmic injection system.
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  52. Fowers, Kirk Dee; Zentner, Gaylen M.; Shih, Chung; Piao, Ai-Zhi, PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water.
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  53. Szymaitis, Dennis W., Periodontal regeneration composition and method of using same.
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  54. Szymaitis, Dennis W., Periodontal regeneration composition and method of using same.
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  55. Chen, Guohua; Priebe, David, Short duration depot formulations.
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  56. Chen, Guohua; Priebe, David T., Short duration depot formulations.
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  57. Pinedjian, Raffi; Sanchez, Jr., Robert J., Spring driven ophthalmic injection device with safety actuator lockout feature.
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  58. Harvie, Fraser; James, Adam; Richardson, Peter; Huckle, James William, Surgical procedures and instruments.
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  59. Harvie,Fraser; Smith,Graham; Sample,Philip B.; McCarthy,Gary R.; James,Adam; Richardson,Peter, Surgical procedures and instruments.
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  60. Wong, Vernon G.; Wood, Louis L., Sustained release eye drop formulations.
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  61. Wong, Vernon G.; Wood, Louis L., Sustained release eye drop formulations.
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  62. Wong, Vernon G.; Wood, Louis L., Sustained release eye drop formulations.
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  63. Dos Santos, Cesario; Sanchez, Jr., Robert J., Temperature control device and thermal sensor assembly for medical device.
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  64. Dacquay, Bruno; Santos, Cesario Dos; Lind, Casey, Temperature release mechanism for injection device.
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  65. Lamoureux, Gary A.; Matons, James; Johnston, Warren; Bouffard, Matthew; Rice, Warren, Therapeutic member including a rail used in brachytherapy and other radiation therapy.
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  66. Irion, Klaus M.; Hahn, Rainer, Use of 5-aminolevulinic acid or a derivate thereof for photodynamic diagnosis and/or photodynamic therapy.
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  67. Schulz, Hans-Herrmann; Schlimbach, Günther, Use of chemotherapeutic agents.
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  68. Roberts F. Donald ; Friden Phillip M. ; Spacciapoli Peter ; Nelson Eric, Use of locally delivered metal ions for treatment of periodontal disease.
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