초록 ▼

Lubricious coatings comprising a binder polymer which is a copolymer of vinyl chloride, vinyl acetate and a carboxylic acid moiety and a hydrophilic polymer are disclosed. The coatings can be applied to a variety of substrates such as, for example, catheters, stents, dilatation balloons, guide wires

Lubricious coatings comprising a binder polymer which is a copolymer of vinyl chloride, vinyl acetate and a carboxylic acid moiety and a hydrophilic polymer are disclosed. The coatings can be applied to a variety of substrates such as, for example, catheters, stents, dilatation balloons, guide wires, endotracheal tubes, instruments, implants and other biomedical devices and can provide exceptional lubricity and abrasion resistance. Processes for applying the lubricious coatings in either one or two coating steps are also disclosed.

대표청구항 ▼

A process for applying a lubricious coating to a surface of a substrate comprising contacting the surface with: (i) a hydrophilic polymer which is substantially more lubricious when wetted with an aqueous liquid than when dry; and (ii) a binder polymer which is a copolymer of vinyl chloride, vinyl a

A process for applying a lubricious coating to a surface of a substrate comprising contacting the surface with: (i) a hydrophilic polymer which is substantially more lubricious when wetted with an aqueous liquid than when dry; and (ii) a binder polymer which is a copolymer of vinyl chloride, vinyl acetate and a carboxylic acid wherein there is less than about 5% of covalent bonding between the binder polymer and the hydrophilic polymer based on the total number of bonding sites between the binder polymer and the hydrophilic polymer.