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Derivatization of solid supports and methods for oligomer synthesis 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B05D-001/36
출원번호 US-0431196 (1995-04-27)
발명자 / 주소
  • Sundberg Steven A. (San Francisco CA) Fujimoto David (Mountain View CA)
출원인 / 주소
  • Affymax Technologies, N.V. (Curacao NLX 03)
인용정보 피인용 횟수 : 287  인용 특허 : 8

초록

Methods and derivatized supports which are useful in solid-phase synthesis of peptides, oligonucleotides or other small organic molecules as well as arrays of ligands. The methods provide means to control the functional site density on a solid support. Some of the derivatized supports are polymer-co

대표청구항

A method for affixing functional sites to the surface of a solid substrate, comprising: (a) contacting said solid substrate with a derivatizaton reagent, said reagent having a substrate attaching group and a reactive site, to covalently bind said substrate attaching group to said substrate and there

이 특허에 인용된 특허 (8)

  1. Hamill Brendan J. (11 ; Napier Square Livingston EH54 5DG GB6), Apparatus for the chemical synthesis of oligonucleotides.
  2. Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof.
  3. Fodor Stephen P. A. (Palo Alto CA) Mazzola Laura T. (Redwood City CA), Method and apparatus for measuring binding affinity.
  4. Venuti Michael C. (San Francisco CA) Bruno John J. (Redwood City CA), Novel w 상세보기
  • Okamoto Yoshio (Amagasaki JPX) Hatada Koichi (Ikeda JPX), Separation agent.
  • Ellman Jonathan A. (Berkeley CA), Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support.
  • Barrett Ronald W. (Sunnyvale CA) Pirrung Michael C. (Durham NC) Stryer Lubert (Stanford CA) Holmes Christopher P. (Sunnyvale CA) Sundberg Steven A. (San Francisco CA), Spatially-addressable immobilization of anti-ligands on surfaces.
  • Buendia Jean (Le Perreux Sur Marne FRX) Nierat Jeanine (Suresnes FRX), Supports and their use.
  • 이 특허를 인용한 특허 (287)

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