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Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/00
  • A61K-031/56
  • A61K-031/19
출원번호 US-0355461 (1994-12-13)
발명자 / 주소
  • Yanni John M. (Burlesson TX)
출원인 / 주소
  • Alcon Laboratories, Inc. (Fort Worth TX 02)
인용정보 피인용 횟수 : 30  인용 특허 : 22

초록

Methods for treating the cornea following laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators and pain mediators to the eye. Compositions for use in treating the cornea are also disclosed.

대표청구항 ▼

A method for treating the cornea for haze or pain following laser irradiation and resulting photoablation of corneal tissue comprising, applying to the affected eye, a therapeutically effective amount of a composition comprising a wound healing modulator and a pain mediator wherein the wound healing

이 특허에 인용된 특허 (22)

  1. York ; Jr. Billie M. (Fort Worth TX), Aldose reductase inhibitors useful in ophthalmic wound healing.
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  2. Woods Gilbert Frederick (Glasgow SC) Cairns James (Cumbernauld SC) McGarry George (Airdrie SC), Alkylated 3,20-diketo-D4-steroids of the pregnane series.
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  3. Boltralik John J. (Fort Worth TX), Anti-inflammatory compounds for ophthalmic use.
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  4. Stewart John M. (Denver CO) Vavrek Raymond J. (Denver CO), Bradykinin antagonist peptides.
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  5. Muller David F. (Boston MA), Corneal treatment agents.
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  6. Carson John R. (Norristown PA), Cyclopenta[b]thiophenes having anti-inflammatory activity similar to steroids.
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  7. Murphy Christopher J. (Davis CA) Reid Ted W. (Davis CA) Mannis Mark J. (Carmichael CA) Foster Bradley A. (Davis CA) Cullor James S. (Woodland CA) Selsted Michael E. (Los Angeles CA) Lehrer Robert I. , Defensin peptide compositions and methods for their use.
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  8. Gnzler Volkmar (Bodenheim DEX) Hanauske-Abel Hartmut (Dexheim DEX) Mohr Jrgen (Bischofsheim DEX) Tschank Georg (Mainz DEX) Kivirikko Kari (Oulu CA FIX) Majamaa Kari (San Pedro CA) Brocks Dietrich (Hn, Esters of pyridine-2,4- and 2,5-dicarboxylic acid as medicaments for the inhibition of proline hydroxylase and lysine hy.
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  9. Clark John I. (Seattle WA) Farr Andrew G. (Seattle WA) Smith Stacia A. (San Diego CA), Immunoregulatory agents.
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  10. L\Esperance ; Jr. Francis A. (Englewood NJ), Method for ophthalmological surgery.
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  11. L\Esperance ; Jr. Francis A. (Englewood NJ), Method for performing ophthalmic laser surgery.
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  12. York ; Jr. Billie M. (Fort Worth TX), Method of inhibiting aldose reductase activity.
    상세보기
  13. Gibson David R. (Irvine CA), Methods and materials for use in corneal wound healing.
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  14. Kludas, Martin, Methods for treating damaged corneal, uterine, or cartilage tissue.
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  15. Han, Wesley W.; Roehrs, Robert E., Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents.
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  16. Haslam John L. (Lawrence KS) Higuchi Takeru (Lawrence KS) Mlodozeniec Arthur R. (Lawrence KS), Ophthalmic drug delivery system utilizing thermosetting gels.
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  17. York ; Jr. Billie M. (Fort Worth TX), Ophthalmic wound healing with aldose reductase inhibitors.
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  18. Robertson Stella M. (Arlington TX) Kunkle ; Jr. Herman M. (Mansfield TX), Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irrad.
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  19. Testa Michele (30 Via Guantai Nuovi 80133 Naples ITX), Pharmaceutical compounds effective against several disorders of the eye in particular the cataract and composition conta.
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  20. York ; Jr. Billie M. (Fort Worth TX), Spiro-(fluoren-9,4′-imidazolidine)-2′,5′-diones.
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  21. Bito Laszlo Z. (New York NY), Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma.
    상세보기
  22. Waterbury L. David (San Mateo CA), Use of pyrrolo pyrroles in treatment of ophthalmic diseases.
    상세보기

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  1. Demopulos, Gregory A.; Palmer, Pamela Pierce; Herz, Jeffrey M., Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation.
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  2. Demopulos, Gregory A.; Pierce Palmer, Pamela; Herz, Jeffrey M., Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation.
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  3. Demopulos, Gregory A.; Pierce Palmer, Pamela; Herz, Jeffrey M., Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation.
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  4. Gyorgy Lajos Kis CH, Autoclavable pharmaceutical compositions containing a chelating agent.
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  5. Kis, Gyorgy Lajos; Adam, Marcia Johanna; Fetz, Andrea, Autoclavable pharmaceutical compositions containing a chelating agent.
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  6. Williams, Lewis T., Combination PDGF, KGF, IGF, and IGFBP for wound healing.
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  7. Beaulieu, Andre; Paquin, Robert, Method of producing concentrated non-buffered solutions of fibronectin.
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  8. Wright, Carol; Llanos, Gerard H.; Rakos, Ronald; King, Kristen; Falotico, Robert, Methods and devices for delivering therapeutic agents to target vessels.
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  9. Aberg, A.K. Gunnar; Johnson, Keith, Methods of treatment of xerophthalmia with self-preserving ocular formulations of norketotifen.
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  10. Reid, Ted; Murphy, Christopher J., Methods of using substance P to promote healing of vascular wounds.
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  11. Mitra, Ashim K.; Velagaleti, Poonam R.; Natesan, Subramanian, Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors.
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  12. Mitra, Ashim K.; Velagaleti, Poonam R.; Natesan, Subramanian, Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors.
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  13. Abelson, Mark; McMullin, Kirk, Ophthalmic formulations and uses thereof.
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  14. Abelson, Mark; McMullin, Kirk; Padilla, Angel, Ophthalmic formulations and uses thereof.
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  15. Demopulos, Gregory A.; Palmer, Pamela Pierce; Herz, Jeffrey M., Ophthalmologic irrigation solutions and method.
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  16. Demopulos, Gregory A.; Palmer, Pamela Pierce; Herz, Jeffrey M., Ophthalmologic irrigation solutions and method.
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  17. Demopulos, Gregory A.; Palmer, Pamela Pierce; Herz, Jeffrey M., Ophthalmologic irrigation solutions and method.
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  18. Demopulos, Gregory A.; Palmer, Pamela Pierce; Herz, Jeffrey M., Ophthalmologic irrigation solutions and method.
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  19. Demopulos, Gregory A.; Palmer, Pamela Pierce; Herz, Jeffrey M., Ophthalmologic irrigation solutions and method.
    상세보기
  20. Beaulieu,Andre; Paquin,Robert; Lariviere,Benoit, Solid wound healing formulations containing fibronectin.
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  21. Demopulos, Gregory A.; Shen, Hui-rong; Tedford, Clark E., Stable preservative-free mydriatic and anti-inflammatory solutions for injection.
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  22. Demopulos, Gregory A.; Shen, Hui-rong; Tedford, Clark E., Stable preservative-free mydriatic and anti-inflammatory solutions for injection.
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  23. Demopulos, Gregory A.; Shen, Hui-rong; Tedford, Clark E., Stable preservative-free mydriatic and anti-inflammatory solutions for injection.
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  24. Fischell, Robert E.; Fischell, David R.; Fischell, Tim A.; Fischell, Scott J. S., Surgically implanted devices having reduced scar tissue formation.
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  25. Mitra, Ashim K.; Velagaleti, Poonam R.; Grau, Ulrich M., Topical drug delivery systems for ophthalmic use.
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  26. Wong, Warren, Topical nepafenac formulations.
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  27. Wong, Warren, Topical nepafenac formulations.
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  28. Aberg, A. K. Gunnar; Johnson, Keith, Treating xerophthalmia with norketotifen.
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  29. Karageozian, Vicken H.; Castillejos, David; Park, John, Treatment of ophthalmic disorders using urea.
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  30. Stiles, Kris R., Veterinary treatment of ophthalmic disease in animals using topical tacrolimus.
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