초록 ▼

A method of administering to the eye a liquid ophthalmic formulation, comprising an ophthalmologically acceptable liquid and optionally containing an ophthalmologically-active substance, characterized in that the formulation has a viscosity in the range 10-3 to 1.0 Pa.s and a resistivity lower than

A method of administering to the eye a liquid ophthalmic formulation, comprising an ophthalmologically acceptable liquid and optionally containing an ophthalmologically-active substance, characterized in that the formulation has a viscosity in the range 10-3 to 1.0 Pa.s and a resistivity lower than 104 ohm.cm, and that a jet of the formulation is ejected towards the eye, from a spray nozzle situated adjacent to a piezoelectric or electromagnetic transducer, to form a stream of uniformly-sized, equally spaced, uncharged droplets, the stream of uncharged droplets is subsequently directed past a charging electrode to induce an electric charge on each droplet in the stream, and the charged droplets discharge their electric charge by earthing on contact with the eye; and spraying apparatus suitable for use in that method.

대표청구항 ▼

A method for administering a liquid ophthalmic formulation to the surface of the eye, said method comprising the steps of: providing a spray nozzle having a liquid outlet in proximity to but spaced from said surface, said nozzle being situated adjacent to a piezoelectric or electromagnetic transduce

A method for administering a liquid ophthalmic formulation to the surface of the eye, said method comprising the steps of: providing a spray nozzle having a liquid outlet in proximity to but spaced from said surface, said nozzle being situated adjacent to a piezoelectric or electromagnetic transducer; providing to said nozzle said liquid ophthalmic formulation comprising an ophthalmologically-acceptable liquid having a viscosity in the range 10-3 to 1.0 Pa.s and a resistivity lower than 104 ohm.cm; ejecting a jet of said formulation from said spray nozzle towards said surface, forming a stream of uniformly-sized, equally spaced, uncharged droplets by means of said transducer; and causing said droplets, upon formation, to pass through the charging field of a charging electrode, thereby inducing an electric charge on each droplet before contacting said surface; whereby the charged droplets discharge their electric charge by earthing on contact with the surface of said eye.