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Method for making freeze dried drug dosage forms 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/20
출원번호 US-0481287 (1995-06-07)
국제출원번호 PCT/US94/07618 (1994-07-08)
§371/§102 date 19950607 (19950607)
국제공개번호 WO-9501782 (1995-01-19)
발명자 / 주소
  • Kearney Patrick (Swindon GB2) Wong Sang K. (New Malden GB2)
출원인 / 주소
  • R.P. Scherer Corporation (Troy MI 02)
인용정보 피인용 횟수 : 111  인용 특허 : 14

초록 ▼

The present invention discloses an improved technique for preparing a rapidly dispersing pharmaceutic tablet of a granular therapeutic agent which has both relatively low solubility and relatively large particle size. Xanthan gum is added to a liquid admixture of solvent, carrier components, and the

대표청구항 ▼

A method of manufacturing a solid, shaped dosage form which disintegrates in lass than about 10 seconds upon contact with an aqueous media, said method including the preparation of a liquid admixture comprising a solvent, gelatin, a granular therapeutic agent having a particle size ranging from abou

이 특허에 인용된 특허 (14)

  1. Gregory George K. E. (Marlow GB2) Peach James M. (High Wycombe GB2) Du Mayne James D. (Maidenhead GB2), Articles for carrying chemicals.
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  2. Guittard George V. (Cupertino CA) Carpenter Howard A. (Palo Alto CA) Quan Ernest S. (Fremont CA) Wong Patrick S. (Palo Alto CA) Hamel Lawrence G. (Sunnyvale CA), Dosage form for delivering drug in short-time period.
    상세보기
  3. Haga Katsuhiko (Shizuoka JPX), Electrostatic recording film.
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  4. Ballester-Rodes Montserrat (Barcelona ESX) Palomo-Nicolau Francisco E. (Barcelona ESX) Palomo-Coli Antonio L. (Barcelona ESX), Famotidine polymorphic forms and their preparation process.
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  5. Blank Robert G. (Hammonton NJ) Mody Dhiraj S. (Hammonton NJ) Kenny Richard J. (Manahawkin NJ) Aveson Martha C. (Voorhees NJ), Fast dissolving dosage forms.
    상세보기
  6. France Gordon (Digswell GB2) Leonard Graham S. (St. Albans GB3), Pharmaceutical compositions.
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  7. Gregory George K. E. (Marlow GB2) Ho David S. S. (Maidenhead GB2), Pharmaceutical dosage form packges.
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  8. Gole Dilip J. (1081 Barton Dr. #202 Ann Arbor MI 48105) Levinson R. Saul (2760 Robal Ct. Saline MI 48176) Carbone James (50333 Willis Rd. ; #227 Belleville MI 48111) Davies J. Desmond (30 Newberry Pl, Preparation of pharmaceutical and other matrix systems by solid-state dissolution.
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  9. Palomo-Coll Antonio L. (Barcelona ESX) Ballester-Rods Montserrat (Barcelona ESX) Polamo-Nicolau Francisco E. (Sant Cugat Del Valles ESX), Process for preparing H2 receptor antagonist ascorbate compounds.
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  10. Bod Pter (Gymro HUX) Harsnyi Klmn (Budapest HUX) Hegeds Bla (Budapest HUX) Bogsch Erik (Budapest HUX) Fekecs va (Budapest HUX) Pter Imre (Budapest HUX) Aracs nTrischler Zsuzsanna (Budapest HUX) Miszo, Process for the preparation of morphologically homogeneous forms of thiazole derivatives.
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  11. Buxton Ian R. (High Wycombe GB2) Feldman Harold (Liphook GB2), Solid shaped articles.
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  12. Roche Edward J. (Hawthorne Place PA), Taste masking and sustained release coatings for pharmaceuticals.
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  13. Hill David T. (North Wales PA) Johnson Randall K. (Ardmore PA), Tetraphosphine-coordinated gold(I) complexes.
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  14. Shaver Sammy R. (Chapel Hill NC) Freeman George A. (Raleigh NC) Rideout Janet L. (Raleigh NC), Therapeutic nucleosides.
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