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Methods for the preparation of nucleic acids for in vivo delivery 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/127
출원번호 US-0483295 (1995-06-07)
발명자 / 주소
  • Grinstaff Mark W. (Pasadena CA) Soon-Shiong Patrick (Los Angeles CA) Wong Michael (Champaign IL) Sandford Paul A. (Los Angeles CA) Suslick Kenneth S. (Champaign IL) Desai Neil P. (Los Angeles CA)
출원인 / 주소
  • Vivorx Pharmaceuticals, Inc. (Santa Monica CA 02)
인용정보 피인용 횟수 : 136  인용 특허 : 0

초록

In accordance with the present invention, there are provided compositions useful for the in vivo delivery of a biologic, wherein the biologic is associated with a polymeric shell formulated from a biocompatible material. The biologic can be associated with the polymeric shell itself, and/or the biol

대표청구항

A method for the preparation of articles for in vivo delivery of nucleic acid constructs, said method comprising subjecting aqueous medium containing biocompatible material capable of being crosslinked by disulfide bonds and nucleic acid construct to high intensity ultrasound conditions for a time s

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