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Method for treating and rendering grafts nonthrombogenic and substantially nonimmunogenic using an extracellular matrix 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-001/02
  • A61F-002/04
출원번호 US-0437155 (1995-05-17)
발명자 / 주소
  • Brasile Lauren (61 Meadow La. Albany NY 12208)
인용정보 피인용 횟수 : 82  인용 특허 : 0

초록 ▼

The present invention is directed to methods and compositions for immunomodifying a graft so that it is nonthrombogenic and substantially nonimmunogenic when transplanted into a recipient. In an ex vivo process, the lumenal surfaces of blood vessels comprising the vasculature within the graft are co

대표청구항 ▼

A method of treating lumenal surfaces in the vasculature of a tissue or organ to be grafted, said method comprises the steps of: (a) removing the organ or tissue to be grafted from the donor, (b) perfusing or infusing the organ or tissue with a preservation solution, (c) coating the vascular endothe

이 특허를 인용한 특허 (82)

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  3. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
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  4. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  5. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  6. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis J.; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  7. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis J.; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
  8. Owen, Donald R.; Kravitz, David C.; Brassil, John; Brockbank, Kelvin G. M.; Burroughs, Andrew; Isaacs, Dickon; Steibel, Dennis; Fraser, Richard; Harris, Stanley; Schein, Douglas, Apparatus and method for maintaining and/or restoring viability of organs.
    상세보기
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